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| 1 | Genetic, metabolic and environmental factors involved in the development of liver cirrhosis in Mexico显示文摘Liver cirrhosis(LC) is a chronic illness caused by inflammatory responses and progressive fibrosis. Globally, the most common causes of chronic liver disease include persistent alcohol abuse, followed by viral hepatitis infections and nonalcoholic fatty liver disease. However, regardless of the etiological factors, the susceptibility and degree of liver damage may be influenced by genetic polymorphisms that are associated with distinct ethnic and cultural backgrounds. Consequently, metabolic genes are influenced by variable environmental lifestyle factors, such as diet, physical inactivity, and emotional stress, which are associated with regional differences among populations. This Topic Highlight will focus on the genetic and environmental factors that may influence the metabolism of alcohol and nutrients in the setting of distinct etiologies of liver disease. The interaction between genes and environment in the current-day admixed population, Mestizo and Native Mexican, will be described. Additionally, genes involved in immune regulation, insulin sensitivity, oxidative stress and extracellular matrix deposition may modulate the degree of severity. In conclusion, LC is a complex disease. The onset, progression, and clinical outcome of LC among the Mexican population are influenced by specific genetic and environmental factors. Among these are an admixed genome with a heterogenic distribution of European, Amerindian and African ancestry; a high score of alcohol consumption; viral infections; a hepatopathogenic diet; and a high prevalence of obesity. The variance in risk factors among populations suggests that intervention strategies directed towards the prevention and management of LC should be tailored according to such population-based features. | Omar Ramos-Lopez Erika Martinez-Lopez Sonia Roman Nora A Fierro Arturo Panduro | 2015 | World Journal of Gastroenterology2015，21，41： | 11 |
| 2 | F- wave study at different stimulation rates in upper motoneurone lesions 显示文摘 | Fierro B Raimondo D Modica A | 1993 | Electromyogr Clin Neurophysiol1993，33，1： | 1 |
| 3 | Unusually high selectivity to C2+ alcohols on bimetallic CoFe catalysts during CO hydrogenation显示文摘 | De la PENA OSHEA V A MENENDEZ N N TORNERO J D FIERRO J L G | 2003 | Catal Lett2003，88，34： | 1 |
| 4 | Tungsten and tungsten carbide supported on activated carbon: Surface structure and performance for ethylene hydrogenation显示文摘 | MORENO C C ALVAREZ M A CARRASCO M F FIERRO J L | 2001 | Langmuir2001，17，5： | 1 |
| 5 | Anatomic study of the lymph nodes of the mesorectum显示文摘 | César E. Canessa M.D. Federica Badía M.D. Socorro Fierro M.D. Verónica Fiol M.D. Gastón Háyek M.D | 2001 | Diseases of the Colon & Rectum2001，，9： | 1 |
| 6 | Decomposition of paper de- inking sludge in a sandpit minesoil during its revegetation 显示文摘 | Fierro A Angers D A Beauchamp C J | 2000 | Soil Biology & Biochemistry2000，32，2： | 1 |
| 7 | Fischer-Tropsch synthesis on mono- and bimetallic Co and Fe catalysts in fixed-bed and slurry reactors显示文摘 | De la PENA OSHEA V A ALVAREZ-GALVANA M C CAMPOS-MARTIN J M FIERRO J L G | 2007 | Appl Catal A2007，326，1： | 1 |
| 8 | Hydrogenation of aromatics over Au-Pd/SiO2-Al2O3 catalysts: Support acidity effect显示文摘 | VENEZIA A M PAROLA V L PAWELEC B FIERRO J L G | 2004 | Appl Catal A2004，264，1： | 1 |
| 9 | A vision-based formation control framework显示文摘 | Das A Fierro R Kumar R | 2002 | IEEE Trans on Robotics and Automation2002，18，5： | 1 |
| 10 | Synthesis,characterization and performance in arsenic removal of iron-doped activated carbons prepared by impregnation with Fe(III) and Fe(II)显示文摘 | Muniz G Fierro V Celzard A | 2009 | Journal of Hazardous Materials2009，165，： | 1 |
| 11 | Photocatalytic hydrogen production on Cd1-xZnxS solid solutions under visible light:Influence of thermal treatment显示文摘 | VILLORIA J A NAVARRO YERGA R M AL-ZAHRANI S M FIERRO J L G | 2010 | Ind Eng Chem Res2010，49，15： | 1 |
| 12 | Applications of the statistical mechanics of inherent states to granular media显示文摘 | Coniglio A Fierro A Nicodemi M | 2001 | PhysicaA2001，302，： | 1 |
| 13 | Dehydrogenation of isopropylic alcohol on a Cu/SiO2 catalyst: a study of the activity evolution and reactivation of the catalyst 显示文摘 | Marchi A J Fierro J L G Santamaría J | 1996 | Appl Catal1996，142，： | 1 |
| 14 | Chemical structures and performance of perovskite oxides显示文摘 | Pene M A Fierro J L G | 2001 | Chemical Reviews2001，101，7： | 1 |
| 15 | Effect of two insecti- cides and two herbicides on the porcine sperm motility pat- terns using computer-assisted semen analysis (CASA) in vitro显示文摘 | Betancourt M Res6ndiz A Fierro E C | 2006 | Reprod Toxicol2006，22，3： | 1 |
| 16 | Highly stable Fe on activated carbon catalysts for CWPO upon FeCl3 activation of lignin from black liquors显示文摘 | ZAZO J A BEDIA J FIERRO C M | 2012 | Catalysis Today2012，187，1： | 1 |
| 17 | Effect of two insecticides and two herbicides on the porcine sperm motility patterns using computer-assisted semen analysis (CASA)in vitro显示文摘 | Betancourt M Resendiz A Fierro E C | 2006 | Fierro Toxicol2006，22，： | 1 |
| 18 | Regeneration of Ni-USY catalysts used in benzene hydrogenation显示文摘 | PAWELEC B DAZA L FIERRO J L G ANDERSON J A | 1996 | Appl Catal A1996，145，12： | 1 |
| 19 | COMODO: an adaptive coclustering strategy to identify conserved coexpression modules between organisms 显示文摘 | ZARRINEH P FIERRO A C SANCHEZ-RODRIGUEZ A | 2011 | Nucleic Acids Research2011，39，7： | 1 |
| 20 | Activated earbons prepared from wood particleboard wastes: charaeterization and phenol adsorption capacities显示文摘 | P Girods A Dufour V Fierro etal | 2009 | Journal of Hazardous Materials2009，166，： | 1 |
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