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| 1 | Portal hypertension in polycystic liver disease patients does not affect wait-list or immediate post-liver transplantation outcomes显示文摘AIM To establish the impact of portal hypertension(PH) on wait-list/post-transplant outcomes in patients with polycystic liver disease(PCLD) listed for liver transplantation. METHODS A retrospective single-centre case controlled study of consecutive patients listed for liver transplantation over 12 years was performed from our centre. PH in the PCLD cohort was defined by the one or more of following parameters:(1) presence of radiological or endoscopic documented varices from our own centre or the referral centre;(2) splenomegaly(> 11 cm) on radiology inabsence of splenic cysts accounting for increased imaging size;(3) thrombocytopenia(platelets < 150 × 109/L); or(4) ascites without radiological evidence of hepatic venous outflow obstruction from a single cyst. RESULTS Forty-seven PCLD patients(F: M = 42: 5) were listed for liver transplantation(LT)(single organ, n = 35; combined liver-kidney transplantation, n = 12) with 19 patients(40.4%) having PH. When comparing the PH group with non-PH group, the mean listing age(PH group, 50.6(6.4); non-PH group, 47.1(7.4) years; P = 0.101), median listing MELD(PH group, 12; non-PH group, 11; P = 0.422) median listing UKELD score(PH group, 48; non-PH group, 46; P = 0.344) and need for renal replacement therapy(P = 0.317) were similar. In the patients who underwent LT alone, there was no difference in the duration of ICU stay(PH, 3 d; non-PH, 2 d; P = 0.188), hospital stay length(PH, 9 d; non-PH, 10 d; P = 0.973), or frequency of renal replacement therapy(PH, 2/8; non-PH, 1/14; P = 0.121) in the immediate post-transplantation period. CONCLUSION Clinically apparent portal hypertension in patients with PCLD listed for liver transplantation does not appear to have a major impact on wait-list or peri-transplant morbidity. | Neil Rajoriya Dhiraj Tripathi Joanna A Leithead Bridget K Gunson Sophie Lord James W Ferguson Gideon M Hirschfield | 2016 | World Journal of Gastroenterology2016，22，45： | 2 |
| 2 | Empirical Evaluation of Preservation Methods for Faecal DNA 显示文摘 | FRANTZEN M A J SILK J B FERGUSON J W H | 1998 | Molecular Ecology1998，7，： | 1 |
| 3 | Pathogenesis of cleft palate in TGF-beta3 knockout mice显示文摘 | Taya Y O' Kane S Ferguson M W | 1999 | Development1999，126，17： | 1 |
| 4 | Current treatment of osteosarcoma 显示文摘 | Ferguson W S Goorin A M | 2001 | Cancer Invest2001，19，： | 1 |
| 5 | Ultrastructural study of early stages of asexual multiplication and microgametogony of Toxo- plasma gondii in the small intestine of the cat显示文摘 | FERGUSON D J P HUTCHISON W M DUNACH- IE J F | 1974 | Acta Pathol Microbiol Scand B Microbiol Immunol1974，82，2： | 1 |
| 6 | Planning for smallpox outbreaks 显示文摘 | Ferguson NM Keeling M J John Edmunds W | 2003 | Nature2003，425，6959： | 1 |
| 7 | The application of embryological studies of alligator farming 显示文摘 | Ferguson M W J | 1981 | Proc Alligator Production Conf (Gainsville Florida)1981，1，： | 1 |
| 8 | Current treatment of Osteosarcoma显示文摘 | FERGUSON W S GOORIN A M | 2001 | Cancer Invest2001，19，： | 1 |
| 9 | The ultrastructural development of the macrogamete and formation of the oocyst wall of Toxoplasma gon- dii显示文摘 | FERGUSON D J P HUTCHISON W M SIIM J C | 1975 | Acta Pathol Microbiol Seand B1975，83，5： | 1 |
| 10 | Tastes and odors:the flavor profile method显示文摘 | Krasner S W McGuire M J Ferguson V B | 1985 | J AWWA1985，77，3： | 1 |
| 11 | Empirical evaluation of preservation methods for faecal DNA显示文摘 | M A J Frantzen J B Silnk J W H Ferguson | 1998 | Molecular Ecology1998，7，： | 1 |
| 12 | The extracellular matrix of lip wounds in fetal, neonatal and adult mice显示文摘 | Whitby D J Ferguson M W | 1991 | Development1991，112，2： | 1 |
| 13 | Male field cricket song reflects age, allowing females to prefer young males 显示文摘 | Verburgt L Ferreira M Ferguson J W H | 2011 | Animal Be- haviour2011，1，81： | 1 |
| 14 | Pseudomonas anguilliseptica infection in farmed cod,Gadus morhua L显示文摘 | FERGUSON H W COLLINS R O MOORE M | 2004 | J Fish Dis2004，27，4： | 1 |
| 15 | Inflamma- tion in carotid atherosclerotic plaque: a dynamic contras- tenhanced MR imaging sudy显示文摘 | Kerwin W O' Brien K Ferguson M | 2006 | Radiology2006，241，2： | 1 |
| 16 | Case-control study of severe life threatening asthma(SLTA) in adults显示文摘 | Kolb J Ferguson W Vanos M | 2002 | J Psychological Factors Thorax2002，57，4： | 1 |
| 17 | Applying ozone for organics control and disinfection:a utility perspective,controlling disinfection by-products显示文摘 | Ferguson D W Gramith J T McGuire M J | 1993 | J AWWA1993，85，1： | 1 |
| 18 | Combining serial analysis of gene expression and array technologies to identify genes differentially expressed in breast cancer 显示文摘 | Nacht M Ferguson AT Zhang W | 1999 | Cancer Res1999，59，： | 1 |
| 19 | Control of scarring in adult wounds by neutralizing antibody to transforming growth factor beta 显示文摘 | Shah M Foreman D M Ferguson M W | 1992 | Lancet1992，339，： | 1 |
| 20 | Tastes and odors:the flavor profile analysis methods显示文摘 | McGuire M J Ferguson V B | 1985 | JAWWA1985，77，： | 1 |
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