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2篇 您的检索式:作者名="Fengting Su"
    题名 作者 年代 出处 被引量
1Capillary bridges and capillary forces between two axisymmetric power-law particles显示文摘Lefeng Wang Fengting Su Huichao Xu Weibin Rong Hui Xie 2016Particuology2016,14,4:2
2Development of a UHPLC-MS/MS method for the quantification of ilaprazole enantiomers in rat plasma and its pharmacokinetic application显示文摘In Korea and China,ilaprazole is a widely used proton pump inhibitor in the treatment of gastric ulcers.In this study,a specific and sensitive LC-MS/MS method has been developed and validated for the quantification of ilaprazole enantiomers in the rat plasma,using R-lansoprazole as the internal standard.The enantioseparation was achieved on a CHIRALPAK AS-RH column(4.6 mm×150 mm,i.d.5 mm),with a mobile phase composed of 10 m M ammonium acetate aqueous solution and acetonitrile(60:40,V/V),at a flow-rate of 0.5 m L/min.The method was validated over the concentration range of 0.5 e300 ng/m L for both,R-and S-ilaprazole.The lower limit of quantification was 0.5 ng/m L for both enantiomers.The relative standard deviation(RSD)of intra-and inter-day precision of R-ilaprazole and S-ilaprazole was less than 10.9%,and the relative error accuracy(RE)ranged fromà0.5%e2.0%.Finally,the method was successfully evaluated in rats in a stereoselective pharmacokinetic study of the ilaprazole racemate.Fengting Ou Ying Zhou Jinxiu Lei Su Zeng Fuhai Wu Ning Zhang Lushan Yu 2020Journal of Pharmaceutical Analysis2020,10,6:0
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