|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Pandemonium Breaks Out:Disruption of Salicylic Acid-Mediated Defense by Plant Pathogens显示文摘Salicylic acid (SA) or 2-hydroxybenoic acid is a phenolic plant hormone that plays an essential role in plant defense against biotrophic and semi-biotrophic pathogens. In Arabidopsis, SA is synthesized from chorismate in the chloroplast through the ICS1 (isochorismate synthase I) pathway during pathogen infectioru The transcription co-activator NPR1 (Non-Expresser of Pathogenesis-Related Gene 1), as the master regulator of SA signaling, interacts with transcription factors to induce the expression of anti-microbial PR (Pathogenesis-Related) genes. To establish successful in fections, plant bacterial, oomycete, fun gal, and viral pathogens have evolved at least three major strategies to disrupt SA-mediated defense? The first strategy is to reduce SA accumulation directly by converting SA into its inactive derivatives. The second strategy is to interrupt SA biosynthesis by targeting the ICS1 pathway. In the third major strategy, plant pathogens deploy different mechanisms to interfere with SA downstream signaling. The wide array of strategies deployed by plant pathogens highlights the crucial role of disruption of SA-mediated plant defense in plant pathogenesis. A deeper understanding of this topic will greatly expand our knowledge of how plant pathogens cause diseases and consequently pave the way for the development of more effective ways to corn trol these diseases. | Guang Qi Jian Chen Ming Chang Huan Chen Katherine Hall John Korin Fengquan Liu Daowen Wang Zheng Qing Fu | 2018 | Molecular Plant2018，11，12： | 5 |
| 2 | The Xanthomonas typeⅢeffector Xop AP prevents stomatal closure by interfering with vacuolar acidification显示文摘Plant stomata close rapidly in response to a rise in the plant hormone abscisic acid(ABA)or salicylic acid(SA)and after recognition of pathogenassociated molecular patterns(PAMPs).Stomatal closure is the result of vacuolar convolution,ion efflux,and changes in turgor pressure in guard cells.Phytopathogenic bacteria secrete typeⅢeffectors(T3Es)that interfere with plant defense mechanisms,causing severe plant disease symptoms.Here,we show that the virulence and infection of Xanthomonas oryzae pv.oryzicola(Xoc),which is the causal agent of rice bacterial leaf streak disease,drastically increased in transgenic rice(Oryza sativa L.)plants overexpressing the Xoc T3E gene Xop AP,which encodes a protein annotated as a lipase.We discovered that Xop AP binds to phosphatidylinositol 3,5-bisphosphate(Ptd Ins(3,5)P_(2)),a memb rane phospholipid that functions in p H control in lysosomes,membrane dynamics,and protein trafficking.Xop AP inhibited the acidification of vacuoles by competing with vacuolar H^(+)-pyrophosphatase(V-PPase)for binding to Ptd Ins(3,5)P_(2),leading to stomatal opening.Transgenic rice overexpressing Xop AP also showed inhibition of stomatal closure when challenged by Xoc infection and treatment with the PAMP flg22.Moreover,Xop AP suppressed flg22-induced gene expression,reactive oxygen species burst and callose deposition in host plants,demonstrating that Xop AP subverts PAMP-triggered immunity during Xoc infection.Taken together,these findings demonstrate that Xop AP overcomes stomatal immunity in plants by binding to lipids. | Longyu Liu Ying Li Zhengyin Xu Huan Chen Jingyi Zhang Brittany Manion Fengquan Liu Lifang Zou Zheng Qing Fu Gongyou Chen | 2022 | Journal of Integrative Plant Biology2022，64，10： | 3 |
| 3 | PBS3 Protects EDS1 from Proteasome-Mediated Degradation in Plant Immunity显示文摘Plant immunity is controlled by both positive regulators such as PBS3 and EDS1 and negative regulators such as NPR3 and NPR4.However,the relationships among these important immune regulators remain elusive.In this study,we found that PBS3 interacts with EDS1 in both the cytoplasm and the nucleus,and is required for EDS1 protein accumulation?NPR3 and NPR4,which function as salicylic acid receptors and adaptors of Cullin3-based E3 ligase,interact with and mediate the degradation of EDS1 via the 26S proteasome.We further discovered that PBS3 inhibits the polyubiquitination and subsequent degradation of EDS1 by reducing the association of EDS1 with the Cullin3 adaptors NPR3 and NPR4.Furthermore,we showed that PBS3 and EDS1 also contribute to PAMP-triggered immunity in addition to effector-triggered immunity.Collectively,our study reveals a novel mechanism by which plants fine-tune defense resporises by inhibiting the degradation of a positive player in plant immunity. | Ming Chang Jinping Zhao Huan Chen Guangyong Li Jian Chen Min Li Ian A.Palmer Junqi Song James R.Alfano Fengquan Liu Zheng Qing Fu | 2019 | Molecular Plant2019，12，5： | 2 |
| 4 | Object request brokers for distributed measurement 显示文摘 | He Feng Wang Fengquan Li Wei Han Xiaolin Liu Jianhua | 2001 | IEEE Computer Applications in Power2001，14，1： | 1 |
| 5 | Hapten heterology for a specific and sensitive indirect enzyme-linked immunosorbent assay for organophosphorus insecticide fenthion显示文摘 | Qi Zhang Laibao Wang Ki Chang Ahn Qin Sun Baishi Hu Jie Wang Fengquan Liu | 2007 | Analytica Chimica Acta2007，，2： | 1 |
| 6 | Development of a sensitive ELISA for the analysis of the organophosphorous insecticide fenthion in fruit samples显示文摘 | Qi Zhang Qin Sun Baishi Hu Qing Shen Gang Yang Xiao Liang Xiao Sun Fengquan Liu | 2007 | Food Chemistry2007，，3： | 1 |
| 7 | The BZR1-EDS1 module regulates plant growth-defense coordination显示文摘Plants have developed sophisticated strategies to coordinate growth and immunity,but our understanding of the underlying mechanism remains limited.In this study,we identified a novel molecular module that reg-ulates plant growth and defense in both compatible and incompatible infections.This module consisted of BZR1,a key transcription factor in brassinosteroid(BR)signaling,and EDS1,an essential positive regulator of plant innate immunity.We found that EDS1 interacts with BZR1 and suppresses its transcriptional activ-ities.Consistently,upregulation of EDS1 function by a virulent Pseudomonas syringae strain or salicylic acid treatment inhibited BZR1-regulated expression of BR-responsive genes and BR-promoted growth.Furthermore,we showed that the cytoplasmic fraction of BZR1 positively regulates effector-triggered im-munity(ETI)controlled by the TIR-NB-LRR protein RPS4,which is attenuated by BZR1's nuclear transloca-tion.Mechanistically,cytoplasmic BZR1 facilitated AvrRps4-triggered dissociation of EDS1 and RPS4 by binding to EDS1,thus leading to efficient activation of RPS4-controlled ETI.Notably,transgenic expression of a mutant BZR1 that accumulates exclusively in the cytoplasm improved pathogen resistance without compromising plant growth.Collectively,these results shed new light on plant growth-defense coordina-tion and reveal a previously unknown function for the cytoplasmic fraction of BZR1.The BZR1-EDS1 mod-ule may be harnessed for the simultaneous improvement of crop productivity and pathogen resistance. | Guang Qi Huan Chen Dian Wang Hongyuan Zheng Xianfeng Tang Zhengzheng Guo Jiayu Cheng Jian Chen Yiping Wang Ming-yi Bai Fengquan Liu Daowen Wang Zheng Qing Fu | 2021 | Molecular Plant2021，14，12： | 1 |
| 8 | Object Request Brokers for Distributed Measuremerit显示文摘 | He Feng Wang Fengquan Li Wei Han Xiaolin and Liu Jianhua | 2001 | IEEE Computer Applications in Power2001，14，1： | 1 |
| 9 | Object Request Brokers for Distributed Measurement显示文摘 | HeFeng Wang Fengquan LiWei HanXiaoLin and Liu Jianhua | 2001 | IEEE Computer Applications in Power2001，14，1： | 1 |
| 10 | Chemistry is key to ECMP efficiency显示文摘 | LIU Fengquan CHEN Liangyu DUBOUST A | 2007 | SemiconductorInternational2007，30，5： | 1 |
| 11 | Development of an immunochromatographic assay for the rapid detection of chlorpyrifos-methyl in water samples显示文摘 | Xiude Hua Guoliang Qian Jifei Yang Baishi Hu Jiaqin Fan Na Qin Gang Li Yuyan Wang Fengquan Liu | 2010 | Biosensors and Bioelectronics2010，，1： | 1 |
| 12 | Identification and molecular characterization of twin-arginine translocation system (Tat) in Xanthomonas oryzae pv. oryzae strain PXO99显示文摘 | Lei Chen Baishi Hu Guoliang Qian Chen Wang Wanfeng Yang Zhicheng Han Fengquan Liu | 2009 | Archives of Microbiology2009，，2： | 1 |
| 13 | ESR Study of the Reaction Between Cp_2Ti(CO)_2 and Cp_2TiBr_2显示文摘Introduction Floriani and Fachinetti have proposed that (Cp2TiCl)2 can be prepared by the reaction between Cp2TiCl2 and Cp2Ti(CO)2. We extended the method to the preparation of (Cp2TiBr)2 and characterized an active intermediate by ESR method. | Wang Jitao, Liu Fengquan Bai Lingjun (Department of Chemistry, Nankai University, Tianjin) | 1991 | Chemical Research in Chinese Universities1991，7，1： | 0 |
| 14 | Evaluation of suitable reference genes for normalization of quantitative real-time PCR analysis in rice plants under Xanthomonas oryzae pv.oryzae--infection and melatonin supplementation显示文摘Exogenous melatonin(MT)was found to be an interesting tool for enhancing the resistance of rice to Xanthomonasoryzaepv.oryzae(Xoo)-caused bacterial blight(BB).However,the accurate comparison of the expression levels across samples was a challenging task.In this work,the stability of 10 common used housekeeping genes under Xoo-infection and MT supplementation in rice was analyzed using quantitative real-time PCR(qRT-PCR),and algorithms geNorm,NormFinder and BestKeeper.Our results indicated that most reference genes remained stable in Xoo-infected rice plants,while a number of reference genes were affected by MT supplementation.Among all studied genes,the transcript levels of 18S(18S ribosomal RNA)and UBC(Ubiquitin-conjugating enzyme E2)remained unaltered by Xoo infection,while UBC and UBQ5(Ubiquitin 5)were the most stable genes when examining simultaneous Xoo-infection and MT supplementation,demonstrating that UBC is a suitable reference gene for qRT-PCR data normalization in rice under Xoo-infection and MT supplementation. | Xian Chen Pedro Laborda Yan Dong Fengquan Liu | 2020 | Food Production, Processing and Nutrition2020，2，1： | 0 |
| 15 | The Tianlai Cylinder Pathfinder array: System functions and basic performance analysis显示文摘The Tianlai Cylinder Pathfinder is a radio interferometer array designed to test techniques for 21 cm intensity mapping in the post-reionization Universe,with the ultimate aim of mapping the large scale structure and measuring cosmological parameters such as the dark energy equation of state.Each of its three parallel cylinder reflectors is oriented in the north-south direction,and the array has a large field of view.As the Earth rotates,the northern sky is observed by drift scanning.The array is located in Hongliuxia,a radio-quiet site in Xinjiang,and saw its first light in September 2016.In this first data analysis paper for the Tianlai cylinder array,we discuss the sub-system qualification tests,and present basic system performance obtained from preliminary analysis of the commissioning observations during 2016-2018.We show typical interferometric visibility data,from which we derive the actual beam profile in the east-west direction and the frequency band-pass response.We describe also the calibration process to determine the complex gains for the array elements,either using bright astronomical point sources,or an artificial on site calibrator source,and discuss the instrument response stability,crucial for transit interferometry.Based on this analysis,we find a system temperature of about 90 K,and we also estimate the sensitivity of the array. | JiXia Li ShiFan Zuo FengQuan Wu YouGang Wang JuYong Zhang ShiJie Sun YiDong Xu ZiJie Yu Reza Ansari YiChao Li Albert Stebbins Peter Timbie YanPing Cong JingChao Geng Jie Hao QiZhi Huang JianBin Li Rui Li DongHao Liu YingFeng Liu Tao Liu John PMarriner ChenHui Niu Ue-Li Pen Jeffery BPeterson HuLi Shi Lin Shu YaFang Song HaiJun Tian GuiSong Wang QunXiong Wang RongLi Wang WeiXia Wang Xin Wang KaiFeng Yu Jiao Zhang BoQin Zhu JiaLu Zhu XueLei Chen | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，12： | 0 |
| 16 | A war on the cell wall显示文摘Plant diseases caused by a wide variety of pathogens have had tremendous negative impacts on human beings.For example,the oomycete pathogen Phytophthora infestans,which causes severe late blight disease on potatoes,triggered the infamous Irish Potato Famine.To prevent such tragedies from happening again and to reduce crop losses,it is imperative to implement effective disease control and management strategies.A deeper and more comprehensive understanding of how plant pathogens cause disease is critical for developing novel and effective strate-gies for controlling plant diseases. | Jian Chen Huan Chen Fengquan Liu Zheng Qing Fu | 2022 | Molecular Plant2022，15，2： | 0 |
| 17 | Connecting the Dots:A New and Complete Salicylic Acid Biosynthesis Pathway显示文摘Salicylic acid(SA) or 2-hydroxybenzoic acid,better known as the active ingredient in aspirin,is a phenolic plant hormone that plays an essential role in plant defense against biotrophic and semi-biotrophic pathogens(Fu and Dong,2013). | Huan Chen Michael Clinton Guang Qi Daowen Wang Fengquan Liu Zheng Qing Fu | 2019 | Molecular Plant2019，12，12： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员