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| 1 | Fabry disease with acute cerebral infarction onset in a young patient显示文摘To the Editor:Fabry disease (FD)is a recessive X-linked hereditary disease.The onset age of the disease is in children and adolescents mostly.The average time from the onset of symptoms to the definite diagnosis needs 13.7 years in male patients and 16.3 years in female patients.FD happens rarely and it is easy to cause diagnosis and treatment delay.Here,we report a case of FD in a 27-year-old man who developed clinical symptoms with acute cerebral infarction onset to improve doctors' understanding of FD. | Ya-Nan Zhang Zhen-Ni Guo Hong-Wei Zhou Ying-Ying Cheng Jia-Chun Feng Zan Wang | 2019 | Chinese Medical Journal2019，，4： | 21 |
| 2 | Using the Prostate Imaging Reporting and Data System version 2 (PI-RIDS v2) to detect prostate cancer can prevent unnecessary biopsies and invasive treatment显示文摘 | Chang Liu Shi-Liang Liu Zhi-Xian Wang Kai Yu Chun-Xiang Feng Zan Ke Liang Wang Xiao-Yong Zeng | 2018 | Asian Journal of Andrology2018，20，5： | 13 |
| 3 | Pirarubicin inhibits multidrug-resistant osteosarcoma cell proliferation through induction of G~/M phase cell cycle arrest显示文摘 | Shui-er ZHENG Sang XIONG Feng LIN Guang-lei QIAO Tao FENG Zan SHEN Da-liu MIN Chun-ling ZHANG Yang YAO | 2012 | Acta Pharmacologica Sinica2012，33，6： | 9 |
| 4 | Self-standing oxygen-deficient a-MoO_(3-x)nanoflake arrays as 3D cathode for advanced all-solid-state thin film lithium batteries显示文摘Compared with the planar two-dimensional(2D)all-solid-state thin film batteries(TFBs),threedimensional(3D)all-solid-state TFBs with interdigitated contact between electrode and electrolyte possess great advantage in achieving both high energy and power densities.Herein,we report a facile fabrication of vertically aligned oxygen-deficient a-MoO3-x nanoflake arrays(3D MO_(x))using metal Mo target by direct current(DC)magnetron sputtering.By utilizing the 3D MO_(x)cathode,amorphous lithium phosphorus oxynitride solid electrolyte,and lithium thin film anode,3D solid-state TFBs have been successfully fabricated,exhibiting high specific capacity(266 mAh g^(-1)at 50 mA g^(-1)),good rate performance(110 mAh g^(-1)at 1000mA g^(-1)),and excellent cycle performance(92.7%capacity retention after 1000 cycles)in comparison with the 2D TFBs using the planar MO_(x)thin film as cathode.The superior electrochemical performance of the 3D TFBs can be attributed to the 3D architecture of the cathode,maximizing the cathode/electrolyte interface while retaining the short Lit diffusion length.The charge/discharge measurements of the 3D MO_(x)cathode in liquid electrolyte,however,exhibit fast capacity fading,demonstrating the advantage of using transition metal oxide as cathode in solid-state batteries. | Shuo Sun Qiuying Xia Jizi Liu Jing Xu Feng Zan Jili Yue Serguei V.Savilov Valery V.Lunin Hui Xia | 2019 | Journal of Materiomics2019，5，2： | 6 |
| 5 | A Study on Integrated Model of Decision Support Systems显示文摘This paper discusses two kinds of systems integrated models available to DSS: Multi-Agent-Based Model and Application-Framework-Oriented Model. Both of them are application-oriented integration so it is possible to combine them at the level of application. Based on this theory, this paper presents a new model, MAAFUM, which combines two models and applies them synthetically in DSS. | MO Zan, FENG Shan, TANG ChaoInstitute of Systems Engineering, Huazhong University of Science and Technology, Wuhan 430074, China | 2002 | Systems Science and Systems Engineering2002，11，3： | 6 |
| 6 | Altered functional connectivity networks of hippocampal subregions in remitted late-onset depression:a longitudinal resting-state study显示文摘在迟了生活的消沉(LLD ) 的海马趾的畸形的地区性的特性在以前的研究被表明了。在这研究,我们寻求了检验功能的连接(FC ) 在汇寄的迟了发作的消沉(rLOD ) 的海马趾的分区的模式, LLD 的一种特殊子类型。十四个 rLOD 病人和 18 健康控制象功能的磁性的回声成像在基线并且在 21 月后续扫描的休息状态一样经历了临床、认知的评估。每马头鱼尾的怪兽被划分成三部分,角 ammonis (CA ) ,有牙齿的回转,和 subicular 建筑群,然后六个基于种子的海马趾的分区网络被建立。六个网络的纵的变化直接随着时间的过去在 rLOD 和控制组之间被比较。从基线到后续,在左 CA 的连接给更大的衰落看到双边的以后的 cingulate cortex/precuneus (PCC/PCUN ) ,但是出现的 rLOD 组与正面的外皮(双边的中间的前额的 cortex/anterior cingulate 外皮和增补马达区域) 增加了恰好海马趾的分区网络的连接。进一步的关联词分析表明在在左 CA 和 PCC/PCUN 之间的 FC 的纵的变化断然在标志位形式测试与纵的变化被相关( r = 0.624 , P = 0.017 )并且位跨度测试( r = 0.545 , P = 0.044 )在 rLOD 组得分。这些结果可以提供卓见进在 rLOD 病人位于认知机能障碍下面的 neurobiological 机制。 | Zan Wang Yonggui Yuan Feng Bai Hao Shu Jiayong You Lingjiang Li Zhijun Zhang | 2015 | Neuroscience Bulletin2015，31，1： | 4 |
| 7 | An injectable and self-healing hydrogel with controlled release of curcumin to repair spinal cord injury显示文摘The harsh local micro-environment following spinal cord injury(SCI)remains a great challenge for neural regeneration.Local reconstitution of a favorable micro-environment by biocompatible scaffolds with desirable functions has thus been an area of concern.Herein,a hybrid hydrogel was developed using Fmoc-grafted chitosan(FC)and Fmoc peptide(FI).Dynamic reversibleπ-πstacking interactions of the fluorenyl rings enabled the FC/FI hybrid hydrogel to exhibit excellent injectable and self-healing properties,as characterized by visual appearances and rheological tests.Furthermore,the FC/FI hybrid hydrogel showed a slow and persistent release of curcumin(Cur),which was named as FC/FI-Cur hydrogel.In vitro studies confirmed that with the support of FC/FI-Cur hydrogel,neurite outgrowth was promoted,and Schwann cell(SC)migration away from dorsal root ganglia(DRG)spheres with enhanced myelination was substantiated.The FC/FI-Cur hydrogel well reassembled extracellular matrix at the lesion site of rat spinal cord and exerted outstanding effects in modulating local inflammatory reaction by regulating the phenotypes of infiltrated inflammatory cells.In addition,endogenous SCs were recruited in the FC/FI-Cur graft and participated in the remyelination process of the regenerated nerves.These outcomes favored functional recovery,as evidenced by improved hind limbs movement and enhanced electrophysiological properties.Thus,our study not only advanced the development of multifunctional hydrogels but also provided insights into comprehensive approaches for SCI repair. | Jinghua Luo Xueshuang Shi Liming Li Zan Tan Feng Feng Jun Li Mao Pang Xiaoying Wang Liumin He | 2021 | Bioactive Materials2021，6，12： | 4 |
| 8 | Impact of exergaming on young children's school day energy expenditure and moderate-to-vigorous physical activity levels显示文摘Background: Although emerging research is demonstrating the potential health impact of exergaming,investigations have primarily been conducted in laboratory settings among small samples with short-term interventions.Information on the effectiveness of exergaming in underserved children's objective physical activity(PA) in population-based settings is also scarce.Moreover,most empirical studies have only included 1 type of exergame in the intervention.Therefore,this study's purpose was to investigate the long-term impact of a multigame exergaming intervention among underserved children integrated within school curricula.Specifically,this study examined the effect of exergaming on children's accelerometer-determined sedentary behavior(SB),light PA,moderate-to-vigorous PA(MVPA),and energy expenditure(EE) over 2 years as compared with regular physical education(PE) classes.Methods: A total of 261 second-and third-grade children(134 girls,127 boys; mean age 8.27 years) were recruited from 2 Texas elementary schools.Children's pre-test 3-day SB,light PA,MVPA,and EE at school were assessed in the fall of 2012.Participants were assigned to 1 of 2groups:(1) exergaming/PE group(125 min weekly of exergaming-based PA program) and (2) comparison group(125 min weekly of PE).PA(SB,light PA,and MVPA) and EE outcome variables were assessed again in 2013(post-test) and 2014(follow-up).Results: Significant time effects were observed for SB(F(1,162)=25.0,p<0.01,η~2= 0.14),light PA(F(1,162)=9.6,p<0.01,η~2= 0.06),and MVPA(F(1,162)=6.2,p=0.01,η~2= 0.04) but not for EE(F(1,162)=0.63,p>0.05,η~2= 0.004).Subsequent pairwise comparisons revealed significant increases from pre-to post-test for light PA(p<0.01),MVPA(p<0.01),and EE(p=0.02) with no changes in SB(p>0.05).Conversely,significant decreases occurred in light PA(p<0.01) from post-test to follow-up with no differences seen in MVPA(p=0.08) and EE(p=0.06) over the same time period.A significant increase was seen,however,for SB from post-test to follow-up.Conclusion: Exergaming PE can have the same positive effect on children's light PA,MVPA,and EE as regular PE.More research is necessary to discern how to promote long-term PA participation after conclusion of the intervention. | Zan Gao Zachary Pope Jung Eun Lee David Stodden Nida Roncesvalles Denis Pasco Charles C.Huang Du Feng | 2017 | Journal of Sport and Health Science2017，6，1： | 3 |
| 9 | MRI feature analysis of uncommon prostatic malignant tumors显示文摘 | Zhao-Yan Feng Xiang-De Min Liang Wang Ba-Sen Li Zan Ke Pei-Pei Zhang Zhen Kang | 2018 | Asian Journal of Andrology2018，20，3： | 2 |
| 10 | Med19 Promotes Osteosarcoma Growth and Metastasis and Associates with Prognosis显示文摘 | Wenxi Yu Zhang Zhichang Min Daliu Yang Qingcheng Du Xuefei Tang Lina Lin Feng Sun Yuanjue Zhao Hui Zheng Shuier He Aina Li Hongtao Yao Yang Zan Shen | 2014 | European Journal of Cancer2014，，： | 1 |
| 11 | Diagnostic Performance and Interobserver Consistency of the Prostate Imaging Reporting and Data System Version 2: A Study on Six Prostate Radiologists with Different Experiences from Half a Year to 17 Years显示文摘 | Zan Ke Liang Wang Xiang-De Min Zhao-Yan Feng Zhen Kang Pei-Pei Zhang Ba-Sen Li Hui-Juan You Sheng-Chao Hou | 2018 | Chinese Medical Journal2018，，14： | 1 |
| 12 | Transplanted endothelial progenitor cells increase neo-vascularisation of rat pre-fabricated flaps显示文摘 | Tao Zan Qing Feng Li Ji Ying Dong | 2010 | J Plast Reconstr Aesthe Surg2010，63，3： | 1 |
| 13 | Study on Application Effect of 6S Management Mode in Infection Control Management of Fangcang Shelter Hospital of National Exhibition and Convention Center显示文摘Objective:In 2022,a pneumonia caused by novel coronavirus broke out in Shanghai.A large number of medical personnel were deployed nationwide to support the Fangcang Shelter Hospital of National Exhibition and Convention Center(Shanghai).Because the of the underdeveloped infrastructure and the disorganized layout process,the phenomenon of infection among medical personnel was rampant given the highly contagious nature of the Omicron variant.This paper discusses the effect of 6S management in infection control management of Fangcang Shelter Hospital of National Exhibition and Convention Center(Shanghai).Methods:A series of 6S management practices were carried out based on the evaluation of the control management of Fangcang Shelter Hospital of National Exhibition and Convention Center(Shanghai)during the anti-epidemic period,and the effect of the implementation of 6S management was studied based on the rapport among team members and the overall control system process,the management of wearing and stripping channels,the time of wearing protective articles and the psychological and emotional changes of the team members.Results:After the implementation of 6S management mode,the management of dressing room,epidemic prevention materials,and occupational protection awareness and infection control safety were significantly improved.More than 95.5%of the team members believed that improving the working environment in the shelter increased the confidence of victory in the fight against the epidemic,reduced the preparations before entering and leaving the cabin,improved the work efficiency and ensured occupational safety.It ensures the realization of the goal of“zero infection”and is set as a benchmark of control work of Fangcang Shelter Hospital of National Exhibition and Convention Center(Shanghai).Conclusion:The application of 6S management mode to the shelter infection control management can create and maintain a good working environment in the shelter,promote the implementation effect of various systems and processes of infection control,reduce the potential infection risk in the shelter and improve the efficiency of infection control management. | Ting Sun Jing Feng Ning Han Ni Li Zhi Zan Dongxian Zhang | 2022 | Journal of Clinical and Nursing Research2022，6，5： | 1 |
| 14 | A novel polymorphism of GDF5 gene and its association with body measurement traits in Bos taurus and Bos indicus breeds显示文摘 | Yong Feng Liu Lin Sen Zan Kui Li Shuan Ping Zhao Ya Ping Xin Qing Lin Wan Qiang Tian Zhi Wei Wang | 2010 | Molecular Biology Reports2010，，1： | 1 |
| 15 | 骨肉瘤血行转移与CXCR4、VEGF相关性研究(英文)显示文摘Objective:We determine whether chemokine receptor CXCR4 and vascular endothelial growth factor(VEGF) expression related to the metastasis and survival outcome of patients with osteosarcoma.Methods:Tissue microarray(TMA) was used to detect the expression of CXCR4 and VEGF in 56 osteosarcoma patient samples.Two-year follow-up was performed to observe the metastatic behavior and overall survival of osteosarcoma patients.Results:There was a significant correlation between the expression levels of CXCR4 and VEGF in 56 osteosarcoma patient samples(P = 0.002).Univariate analysis revealed the expression of CXCR4 and VEGF was not associated with age, gender and the level of ALP but associated with clinical stage.Conclusion:These data raises the possibility that VEGF could regulate the levels of CXCR4 to promote the migration of tumor cells to target organs.CXCR4 and VEGF expression are highly correlated with metastatic progression in patients with osteosarcoma and their immunohistochemical expression have predictive value for the metastatic development. | Feng Lin Shuier Zheng Zan Shen Lina Tang Ping Chen Yuanjue Sun Hui Zhao Yang Yao | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，5： | 1 |
| 16 | Destructive effect of percutaneous hydrochloric acid injection therapy for liver: a preliminary experimental and clinical study 显示文摘 | Feng Weijian Liu Zan Han Suhong | 2006 | Jpn J Cancer and Chemotherapy2006，33，： | 1 |
| 17 | Low-Temperature Synthesis of Crystalline Inorganic/Metallic Nanocrystal-Halloysite Composite Nanotubes显示文摘We have demonstrated a facile approach for the low-temperature synthesis of crystalline inorganic/metallic nanocrystal-halloysite composite nanotubes by employing the bulk controlled synthesis of inorganic/metallic nanocrystals on halloysite nanotubes.The halloysite clay nanotubes can adsorb the target precursor and induce inorganic/metallic nanocrystals to grow in situ.The crystalline phase and morphology of the composite clay nanotubes is tunable.By simply tuning the acidity of the titania sol,the crystalline titania-clay nanotubes with tunable crystalline phases of anatase,a mixture of anatase and rutile or rutile are achieved.The approach is general and has been extended to synthesize the representative perovskite oxide(barium and strontium titanate)-halloysite composite nanotubes.Metallic nickel nanocrystal can also be grown on the surface of halloysite nanotubes at low temperature.The traditional thermal treatment for crystallite transformation is not required,thus intact contour of halloysite nanotubes and the crystallinity structure of halloysite nanotubes can be guaranteed.The combined properties from inorganic/metallic nanocrystal(high refractive index,high dielectric constant and catalytic ability)and the halloysite clay nanotubes are promising for applications such as photonic crystals,high-k-gate dielectrics,photocatalysis and purification. | Cuiping Li Jiaqiang Wang Siquan Feng Zan Liu | 2014 | Chinese Journal of Chemistry2014，32，7： | 1 |
| 18 | Complex genetic architecture underlying the plasticity of maize agronomic traits显示文摘Phenotypic plasticity is the ability of a given genotype to produce multiple phenotypes in response to changing environmental conditions.Understanding the genetic basis of phenotypic plasticity and establishing a predictive model is highly relevant to future agriculture under a changing climate.Here we report findings on the genetic basis of phenotypic plasticity for 23 complex traits using a diverse maize population planted at five sites with distinct environmental conditions.We found that latituderelated environmental factors were the main drivers of across-site variation in flowering time traits but not in plant architecture or yield traits.For the 23 traits,we detected 109 quantitative trait loci(QTLs),29 for mean values,66 for plasticity,and 14 for both parameters,and 80%of the QTLs interacted with latitude.The effects of several QTLs changed in magnitude or sign,driving variation in phenotypic plasticity.We experimentally validated one plastic gene,ZmTPS14.1,whose effect was likely mediated by the compensation effect of ZmSPL6 from a downstream pathway.By integrating genetic diversity,environmental variation,and their interaction into a joint model,we could provide site-specific predictions with increased accuracy by as much as 9.9%,2.2%,and 2.6%for days to tassel,plant height,and ear weight,respectively.This study revealed a complex genetic architecture involving multiple alleles,pleiotropy,and genotype-byenvironment interaction that underlies variation in the mean and plasticity of maize complex traits.It provides novel insights into the dynamic genetic architecture of agronomic traits in response to changing environments,paving a practical way toward precision agriculture. | Minliang Jin Haijun Liu Xiangguo Liu Tingting Guo Jia Guo Yuejia Yin Yan Ji Zhenxian Li Jinhong Zhang Xiaqing Wang Feng Qiao Yingjie Xiao Yanjun Zan Jianbing Yan | 2023 | Plant Communications2023，4，3： | 1 |
| 19 | Destructive effect of percutaneuos hydrochloric acid injection therapy foe liver cancer,-A preliminary experimental and clinical study显示文摘 | Feng Weijian Liu Zan Han Suhong | 2006 | Japanese Journal of Cancer and Chemotherapy2006，33，12： | 1 |
| 20 | Improved magnetic anisotropy of Co-based multilayer film with nitrogen dopant显示文摘Modulating the magnetic anisotropy of ferromagnetic thin films is crucial for constructing high-density and energy efficient magnetic memory devices. Ta/W(N)/Co/Pt multilayers were deposited on silicon substrates by magnetron sputtering at room temperature. The influences of N dopant on the magnetic anisotropy of the multilayers were investigated by preparing the sample with N incorporation. The results indicate that when sputtering W target with only argon gas(Ar), Ta/W/Co/Pt sample shows inplane magnetic anisotropy(IMA). When sputtering W target at a different amount of N_(2) and Ar atmosphere, it can induce perpendicular magnetic anisotropy(PMA) for proper N-doped Ta/W(N)/Co/Pt sample. When the gas flow ratio of Ar:N_(2) is 16:6, the effective magnetic anisotropy constant reach its maximum value of 1.68×10^(5) J·m^(-3),which enhanced by about 400% than our past works(annealing treatment is necessary to induce PMA in Pt/Co/MgO system). X-ray diffraction(XRD) and X-ray reflection(XRR) results demonstrate that N dopants can effectively promote the formation of b-W phase and reduce the roughness of W(N)/Co interface, which are beneficial for PMA. X-ray electron spectroscopy(XPS) analysis reveals that N doping redistributes Co charges, nitrogen ions participate in electron allocation of Co and attract some electrons of Co to form orbital hybridization between Co3 d and N 2 p. This may be another important reason for the PMA formation. | Ling-Ran Yu Xiu-Lan Xu Yun-Long Jia Xuan Geng Xu-Jie Ma Yi-Fei Ma Yong-Hui Zan Chun Feng Jiao Teng | 2021 | Rare Metals2021，40，10： | 1 |
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