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| 1 | From concept to reality-A review to the primary test stand and its preliminary application in high energy density physics显示文摘Pulsed power technology,whereas the electrical energy stored in a relative long period is released in much shorter timescale,is an efficient method to create high energy density physics(HEDP)conditions in laboratory.Around the beginning of this century,China Academy of Engineering Physics(CAEP)began to build some experimental facilities for HEDP investigations,among which the Primary Test Stand(PTS),a multi-module pulsed power facility with a nominal current of 10 MA and a current rising time~90 ns,is an important achievement on the roadmap of the electro-magnetically driven inertial confinement fusion(ICF)researches.PTS is the first pulsed power facility beyond 10 TW in China.Therefore,all the technologies have to be demonstrated,and all the engineering issues have to be overcome.In this article,the research outline,key technologies and the preliminary HEDP experiments are reviewed.Prospects on HEDP research on PTS and pulsed power development for the next step are also discussed. | Jianjun Deng Weiping Xie Shuping Feng Meng Wang Hongtao Li Shengyi Song Minghe Xia Ji Ce An He Qing Tian Yuanchao Gu Yongchao Guan Bin Wei Xianbin Huang Xiaodong Ren Jiakun Dan Jing Li Shaotong Zhou Hongchun Cai Siqun Zhang Kunlun Wang Qiang Xu Yujuan Wang Zhaohui Zhang Guilin Wang Shuai Guo Yi He Yiwei Zhou Zhanji Zhang Libing Yang Wenkang Zou | 2016 | Matter and Radiation at Extremes2016，1，1： | 19 |
| 2 | Folate receptor-mediated boron-10 containing carbon nanoparticles as potential delivery vehicles for boron neutron capture therapy of nonfunctional pituitary adenomas显示文摘Invasive nonfunctional pituitary adenomas(NFPAs) are difficult to completely resect and often develop tumor recurrence after initial surgery.Currently,no medications are clinically effective in the control of NFPA.Although radiation therapy and radiosurgery are useful to prevent tumor regrowth,they are frequently withheld because of severe complications.Boron neutron capture therapy(BNCT) is a binary radiotherapy that selectively and maximally damages tumor cells without harming the surrounding normal tissue.Folate receptor(FR)-targeted boron-10 containing carbon nanoparticles is a novel boron delivery agent that can be selectively taken up by FR-expressing cells via FR-mediated endocytosis.In this study,FR-targeted boron-10 containing carbon nanoparticles were selectively taken up by NFPAs cells expressing FR but not other types of non-FR expressing pituitary adenomas.After incubation with boron-10 containing carbon nanoparticles and following irradiation with thermal neutrons,the cell viability of NFPAs was significantly decreased,while apoptotic cells were simultaneously increased.However,cells administered the same dose of FR-targeted boron-10 containing carbon nanoparticles without neutron irradiation or received the same neutron irradiation alone did not show significant decrease in cell viability or increase in apoptotic cells.The expression of Bcl-2 was down-regulated and the expression of Bax was up-regulated in NFPAs after treatment with FR-mediated BNCT.In conclusion,FR-targeted boron-10 containing carbon nanoparticles may be an ideal delivery system of boron to NFPAs cells for BNCT.Furthermore,our study also provides a novel insight into therapeutic strategies for invasive NFPA refractory to conventional therapy,while exploring these new applications of BNCT for tumors,especially benign tumors. | DAI CongXin CAI Feng HWANG Kuo Chu ZHOU YongMao ZHANG ZiZhu LIU XiaoHai MA SiHai YANG YaKun YAO Yong FENG Ming BAO XinJie LI GuiLin WEI JunJi JIAO YongHui WEI ZhenQing MA WenBin WANG RenZhi | 2013 | Science China(Life Sciences)2013，56，2： | 8 |
| 3 | Efficacy of Bushenjianpi prescription on autoimmune premature ovarian failure in mice显示文摘OBJECTIVE: To assess the efficacy of Bushenjianpi prescription(BSJPP), a formula from Traditional Chinese Medicine, on a mouse model of autoimmune premature ovarian failure(POF) induced by mouse zona pellucida(ZP3) and to investigate the mechanisms underlying the action.METHODS: After randomization, POF was induced in the model mice by immunization with ZP3. One week later, mice received low(8.1 mg/kg), moderate(16.2 mg/kg) and high(32.4 mg/kg) doses of BSJPP by gastrogavage once daily for 90 days. Premarin(0.03 mg/kg) served as the positive group. Serum samples were collected 1 week after the last dose and stored at-20 ℃ for analysis. After cervical dislocation, the uterus and ovaries were collected aseptically for evaluation by histological assessment, scanning electron microscopy, immunohistochemical staining, and Western blot and reverse transcription-polymerase chain reaction analyses.RESULTS: Serum E2 levels in POF model mice were decreased, whereas follicle-stimulating hormone(FSH) and luteinizing hormone(LH) levels were dramatically increased. Serum levels of E2,LH and FSH were reduced in POF model mice treated with BSJPP(moderate and high doses) and premarin. Anti-bone morphogenetic protein 15(BMP-15) and connexin 43(Cx43) were repressed in autoimmune POF model mice, whereas high expression was observed in control mice and those treated with BSJPP(moderate and high doses)and premarin.CONCLUSION: BSJPP is effective in treating ZP3-induced POF in mice and the increase in the expression of BMP-15 and Cx43 may be implicated in the mechanism underpinning the action. | Feng Guilin Lin Meijiao Zhou Xiaolin Zhang Lihong Li Jing Ouyang Jingfeng | 2017 | Journal of Traditional Chinese Medicine2017，37，5： | 6 |
| 4 | Studies of negative pragmatic transfer in interlanguage pragmatics显示文摘Negative pragmatic transfer (NPT) is nothing but a difference of saying things between non native speakers and native speakers. It occupies an important position in interlanguage pragmatics whose mission is to scrutinize how non native speakers do things with words with L2. This paper reported that 4 NPT related aspects have been heavily documented in the current literature: 1) L1 negative pragmatic transfers at the speech act level; 2) the distinction between negative pragmalinguistic and sociopragmatic transfers; 3) conditions of negative pragmatic transfers; and 4) native speaker’s attitudes towards L1 negative pragmatic transfers. Consequently, issues for future studies are also raised. | LIU Shao zhong, LIAO Feng rong (Foreign Languages College,Guangxi Normal University, Guilin 541004, China) | 2002 | 广西师范大学学报(哲学社会科学版)2002，38，S2： | 3 |
| 5 | Synchrotron radiation XRF microprobe investigation of elemental distribution in femoral head slice with osteoporosis显示文摘This note deals with the scanning of femoral head slices from both normal and osteoporosis subjects using synchrotron radiation X-ray fluorescence (SRXRF) microprobe technique. The sample preparation and experimental apparatus are described in detail. The quantitative computerized tomography (QCT) of elemental distribution, such as Ca, P, K, Fe, Zn, Sr and Pb in bone slice tissue including cartilage, substantial compact and substantial spongy, is investigated. Combined with the correlation between P, K, Zn, Sr and Ca, the loss way of minerals and the physiological functions of some metal elements in bone are also discussed. | ZHANG Yuanxun CHENG Feng LI Deyi WANG Yinsong ZHANG Guilin XU Hongjie LIAO Wensheng TANG Tingling HUANG Yuying HE Wei | 2001 | Chinese Science Bulletin2001，46，13： | 3 |
| 6 | Shell effect and capture cross sections in the synthesis of superheavy nuclei显示文摘The shell effect is included in the improved isospin dependent quantum molecular dynamics model in which the shell correction energy of the system is calculated by using the deformed two-center shell model.A switch function is introduced to connect the shell correction energy of the projectile and the target with that of the compound nucleus during the dynamical fusion process.It is found that the calculated capture cross sections reproduce the experimental data quantitatively at the energy near the Coulomb barrier.The capture cross sections for reaction 8305 Br + 28028 Pb → 121878X are also calculated and discussed. | DU SaiSai1,2,BIAN BaoAn1,2,3,LIU Min1,2,4,FENG ZhaoQing5,6 & ZHANG FengShou1,2,6 1 Key Laboratory of Beam Technology and Material Modification of Ministry of Education,College of Nuclear Science and Technology,Beijing Normal University,Beijing 100875,China 2 Beijing Radiation Center,Beijing 100875,China 3 School of Science,Jiangnan University,Wuxi 214122,China 4 College of Physics and Technology,Guangxi Normal University,Guilin 541004,China 5 Institute of Modern Physics,Chinese Academy of Sciences,Lanzhou 730000,China 6 Center of Theoretical Nuclear Physics,National Laboratory of Heavy Ion Accelerator of Lanzhou,Lanzhou 730000,China | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，10： | 2 |
| 7 | Components in Antineoplastic Actinomycete Strain (N2010-37) of Bottom Mud in Mangrove显示文摘Objective To study the antitumor components from an actinomycete strain(N2010-37) of bottom mud in Zhanjiang Mangrove,South China Sea.Methods The components were isolated and purified by chromatographic techniques and recrystallization,and the structures were identified by spectral methods together with physicochemical analyses.The antitumor effects of these components were tested in vitro by MTT method.Results Three compounds were identified including two anthrones and one novel lactone.They are(3S,4R,7R,8R,9S)-3,8-dihydroxy-4,7,9-trimethyl-2,6-cyclononanediolacetone(1) ,2-hydroxy-1-methoxy-3-methylanthraquinone(2) ,and 1,6,8-thihydroxy-3-methylanthraquinone(3) .Conclusion Compound 1 is a new compound,and compounds 1 and 3 show the favorable cytotoxic activities against human chronic granulocytic leukemia cell line K562 strain by MTT method in vitro. | ZHOU Zhong-liu1,2,JIN Bei1,YIN Wen-qing2,FU Chun-yan2,FENG Hua-fen2 1.Chemistry Science and Technology School,Zhanjiang Normal University,Zhanjiang 524048,China 2.Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources,Ministry of Education,School of Chemistry and Chemical Engineering,Guangxi Normal University,Guilin 541004,China | 2011 | Chinese Herbal Medicines2011，3，3： | 2 |
| 8 | Numerically quantifying the relative importance of topography and buoyancy in driving groundwater flow显示文摘Both topography and buoyancy can drive groundwater flow;however,the interactions between them are still poorly understood.In this paper,the authors conduct numerical simulations of variable-density fluid flow and heat transport to quantify their relative importance.The finite element modeling experiments on a 2-D conceptual model reveal that the pattern of groundwater flow depends largely upon the relative magnitude of the flow rate due to topography alone and the flow rate due to buoyancy alone.When fluid velocity due to topography is greater than that due to buoyancy at large water table gradients,topography-driven 'forced convection' overwhelms buoyancy-driven 'free convection'.When flow velocity due to buoyancy is greater than that due to topography at small water table gradients,mixed free and forced convection takes place.In this case,free convection becomes dominant,but topography-driven flow still plays an important role since it pushes the free convection cells to migrate laterally in the downhill direction.Consequently,hydrothermal fluid flow remains changing periodically with time and no steady state can be reached.The presence of a low-permeability layer near the surface helps eliminate the topography effect on the underlying free convection. | YANG JianWen 1,2,FENG ZuoHai 1,LUO XianRong 1 & CHEN YuanRong 1 1 Faculty of Earth Sciences,Guilin University of Technology,Guilin 541004,China 2 Department of Earth and Environmental Sciences,University of Windsor,Windsor,Ontario,N9B 3P4,Canada | 2010 | Science China Earth Sciences2010，53，1： | 2 |
| 9 | Comments on aPractical(t,n)Threshold Proxy Signature Scheme Based on theRSA Cryptosystem显示文摘 | Wang Guilin Feng Bao Zhou Jianying | 2004 | IEEE Transactions on Knowledge and DataEngineering2004，16，10： | 1 |
| 10 | Virus-inspired surface-nanoengineered antimicrobial liposome:A potential system to simultaneously achieve high activity and selectivity显示文摘Enveloped viruses such as SARS-CoV-2 frequently have a highly infectious nature and are considered effective natural delivery systems exhibiting high efficiency and specificity.Since simultaneously enhancing the activity and selectivity of lipopeptides is a seemingly unsolvable problem for conventional chemistry and pharmaceutical approaches,we present a biomimetic strategy to construct lipopeptide-based mimics of viral architectures and infections to enhance their antimicrobial efficacy while avoiding side effects.Herein,a surface-nanoengineered antimicrobial liposome(SNAL)is developed with the morphological features of enveloped viruses,including a moderate size range,lipid-based membrane structure,and highly lipopeptide-enriched bilayer surface.The SNAL possesses virus-like infection to bacterial cells,which can mediate high-efficiency and high-selectivity bacteria binding,rapidly attack and invade bacteria via plasma membrane fusion pathway,and induce a local“burst”release of lipopeptide to produce irreversible damage of cell membrane.Remarkably,viral mimics are effective against multiple pathogens with low minimum inhibitory concentrations(1.6-6.3μg mL1),high bactericidal efficiency of>99%within 2 h,>10-fold enhanced selectivity over free lipopeptide,99.8%reduction in skin MRSA load after a single treatment,and negligible toxicity.This bioinspired design has significant potential to enhance the therapeutic efficacy of lipopeptides and may create new opportunities for designing next-generation antimicrobials. | Yin Shi Xiaoqian Feng Liming Lin Jing Wang Jiaying Chi Biyuan Wu Guilin Zhou Feiyuan Yu Qian Xu Daojun Liu Guilan Quan Chao Lu Xin Pan Jianfeng Cai Chuanbin Wu | 2021 | Bioactive Materials2021，6，10： | 1 |
| 11 | Cryptanalysis of A proxy-protected Proxy Signature Scheme Based on Elliptic Curve cryptosystem 显示文摘 | Shugong Wang Guilin Wang Feng Bao Jie Wang | 2004 | 0-7803-8521-7/04IEEE2004，，： | 1 |
| 12 | Security notes on generalization of threshold signature and authenticated encryption for group communication显示文摘 | Wang Shuhong Wang Guilin Bao Feng | 2004 | IEICE Transactions on Fundamentals2004，872，12： | 1 |
| 13 | 2D and 3D orientation mapping in nanostructured metals: A review显示文摘Nanostructured metals possess various excellent properties and offer the potential for a wide range of applications.Improvements in the properties and performance of nanostructured metal components motivate a complete characterization of the microstructures and crystallographic orientations of nanostructured metals with nanoscale spatial resolution.Two well developed orientation mapping techniques for such characterization are electron backscatter diffraction(EBSD)in the scanning electron microscope and precession electron diffraction(PED)using diffraction spots in the transmission electron microscope.However,these methods can only characterize the structure in two dimensions.It is still a great challenge to characterize grains in three dimensions,i.e.from the interior of the nanostructured metals.Recently,three-dimensional orientation mapping in the transmission electron microscope(3 D-OMi TEM)was developed and further improvements of this technique are introduced in this paper.Utilization of these orientation mapping techniques for structural and orientational characterizations are demonstrated by examples of surface-deformed metals with gradient nanostructures,and a sputtered gold film of nano-islands containing nanograins.The merits and challenges of each of these techniques are discussed and suggestions for further developments are proposed. | Guilin Wu Wanquan Zhu Qiongyao He Zongqiang Feng Tianlin Huang Ling Zhang SØren Schmidt Andrew Godfrey Xiaoxu Huang | 2020 | Nano Materials Science2020，2，1： | 1 |
| 14 | Security notes on generalization of threshold signature and authenticated encryption for group communication显示文摘 | Shuhong Wang Guilin Wang Feng Bao Jie Wang | 2004 | IEICE Transactions on Fundamentals2004，87，12： | 1 |
| 15 | Total and speciated arsenic levels in rice from China 显示文摘 | LIANG Feng LI Yulan ZHANG Guilin | 2010 | Food AdditContam Part A Chem Anal Control Exp Risk A ss2010，27，6： | 1 |
| 16 | The up-regulation of voltage-gated sodium channels subtypes coincides with an increased sodium current in hippocampal neuronal culture model显示文摘 | Feng Guo Xiaoxue Xu Jiqun Cai Huiyuan Hu Wei Sun Guilin He Dongxue Shao Lei Wang Tianbao Chen Chris Shaw Tong Zhu Liying Hao | 2013 | Neurochemistry International2013，，3： | 1 |
| 17 | Security notes on generalization of threshold signature and authenticated encryption for group communication显示文摘 | Wang Shuhong Wang Guilin Bao Feng | 2004 | IEICE Transactions on Fundamentals2004，87，12： | 1 |
| 18 | Microwave Synthesis of Au Nanoparticles with the System of AuCl_4-CH_3CH_2OH显示文摘The Au nanoparticles has been prepared by microwave high-pressure procedure with alcohol as the reducing agent. The color of colloidal Au nanoparticles is blue-violet. The maximum absorption spectrum of colloidal Au is at 580 nm, and the resonance scattering peak is at 580 nm. Using this method, the colloidal Au of long-time stability can be prepared simply and quickly. | Zhi Liang JIANG*, Zhong Wei FENG, Xing Can SHEN Institution of New Technology and Material, Guang Xi Normal University, Guilin 541004 | 2001 | Chinese Chemical Letters2001，12，6： | 0 |
| 19 | A CONTROL OBSERVATION ON THERAPEUTIC EFFECTS OF INTELLIGENT(COMPUTERIZED)ELECTROACUPUNCTURE AND COMMON ELECTROACUPUNCTURE TREATING 77 CASES OF NEUROSIS显示文摘77 cases of neurosis were treated with intelligent(computerized)elec-troacupuncture(IEA)and common electroacupuncture(CEA)at two different wave forms and fre-quencies.The results showed that the markedly effective rates of IEA and CEA were respectively75% and 60% without a statistically significant difference.For different subtypes of neurosis,thetherapeutic effects of IEC in the treatment 6f neurasthenia and depressive neurosis were superior toand in the treatment of anxiety was inferior to those of CEA.For different syndromes,the curativeeffects of IEA on somatic symptom,depression and asthenic symptom were.superior to and on anxietyand sleep-disorder were not as good as those of CEA. | Luo Hechun Jia Yunkui Zhou Aimin Lu Linglin Feng Xiuqin Zhao Xueying. Institute of Mental Health,Beijing Medical University,Beijing 100083,China *Xiangfan Municipal Hospital of Mental Rehabilitation,Hubei Province,China.**The Second Guilin District Hospital,Guangxi Province,China. | 1993 | World Journal of Acupuncture-Moxibustion1993，3，2： | 0 |
| 20 | ALMOST PERIODIC SOLUTIONS TO SOME NONLINEAR DELAY DIFFERENTIAL EQUATION显示文摘The existence of an almost periodic solutions to a nonlinear delay diffierential equation is considered in this paper. A set of sufficient conditions for the existence and uniqueness of almost periodic solutions to some delay diffierential equations is obtained. | Chunhua Feng (College of Mathematical Science, Guangxi Normal University, Guilin 541004, Guangxi) | 2009 | Annals of Differential Equations2009，25，4： | 0 |
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