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| 1 | Consensus statement on the epidemiology,diagnosis,prevention,and management of cow's milk protein allergy in the Middle East:a modified Delphi-based study显示文摘Background This study aimed to develop an expert consensus regarding the epidemiology,diagnosis,and management of cow’s milk protein allergy(CMPA)in the Middle East.Methods A three-step modified Delphi method was utilized to develop the consensus.Fifteen specialized pediatricians participated in the development of this consensus.Each statement was considered a consensus if it achieved an agreement level of>80%.Results The experts agreed that the double-blind placebo-controlled oral challenge test(OCT)should be performed for 2-A weeks using an amino acid formula(AAF)in formula-fed infants or children with suspected CMPA.Formula-fed infants with confirmed CMPA should be offered a therapeutic formula.The panel stated that an extensively hydrolyzed formula(eHF)is indicated in the absence of red flag signs.At the same time,the AAF is offered for infants with red flag signs,such as severe anaphylactic reactions.The panel agreed that infants on an eHF with resolved symptoms within 2-4 weeks should continue the eHF with particular attention to the growth and nutritional status.On the other hand,an AAF should be considered for infants with persistent symptoms;the AAF should be continued if the symptoms resolve within 2-4 weeks,with particular attention to the growth and nutritional status.In cases with no symptomatic improvements after the introduction of an AAF.other measures should be followed.The panel developed a management algorithm,which achieved an agreement level of 90.9%.Conclusion This consensus document combined the best available evidence and clinical experience to optimize the management of CMPA in the Middle East. | Moustafa A.El-Hodhod Mortada H.F.El-Shabrawi Ahmed AIBadi Ahmed Hussein AM Almehaidib Basil Nasrallah Ebtsam Mohammed AIBassam Hala El Feghali Hasan M.Isa Khaled Al Saraf Maroun Sokhn Mehdi Adeli Najwa Mohammed Mousa Al-Sawi Pierre Hage Suleiman Al-Hammadi | 2021 | World Journal of Pediatrics2021，17，6： | 3 |
| 2 | Preliminary ossiculoplasty results using the Kurz titanium prostheses 显示文摘 | Krueger W W Feghali J G Shelton C | 2002 | Otol Neurotol2002，23，6： | 1 |
| 3 | Blunt mycardial injury 显示文摘 | Feghali NT Prisant LM | 1995 | Chest1995，108，6： | 1 |
| 4 | Spatiotemporal motion boundary detection and motion boundary velocity estimation for tracking moving objects with a moving camera; a level sets PDEs approach with concurrent camera motion compensation显示文摘 | Feghali R Mitiche A | 2004 | IEEE Transactions on Image Processing2004，13，11： | 1 |
| 5 | Posterior stabilization of subaxial cervical spine trauma: indications and techniques 显示文摘 | Sundaresan N Shah J Feghali JG | 2005 | Injury Int J2005，36，： | 1 |
| 6 | Adverse Outcomes and Potential Targets for Intervention in Gestational Diabetes and Obesity显示文摘 | Scifres C Feghali M Althouse AD | 2015 | Obstet Gynecol2015，126，2： | 1 |
| 7 | Blunt myocardial injury显示文摘 | Prisant LM | 1995 | Chest1995，108，6： | 1 |
| 8 | A transstemal approach to the upper thoracic vertebrac显示文摘 | Sundaresan N Shah J Feghali JG | 1984 | Am J Surg1984，148，4： | 1 |
| 9 | Cytokines in acute and chronic inflammation显示文摘 | Feghali C A Wright T M | | 0，，： | 1 |
| 10 | Results of aplenectomy for idiopathic thrombocytopenic purpura 显示文摘 | Naouri A Feghali B Chabal J | 1993 | Acta Hematol1993，89，： | 1 |
| 11 | A transternal approach to the upper thoracic vertebrae显示文摘 | Sunderesan N Shah J Feghali JG | 1984 | Am J Surg1984，148，： | 1 |
| 12 | Cytokines in acute and chronic inflammation显示文摘 | Feghali C A Wright T M | 1997 | Front Biosci1997，2，： | 1 |
| 13 | Is the Fowler-Stephens procedure still indicated for the treatment of nonpalpable intraabdominal testis?显示文摘 | Daher P Nabbout P Feghali J | 2009 | J Pediatr Surg2009，44，10： | 1 |
| 14 | Multiplex qPCR for detection and absolute quantification of malaria显示文摘 | Kamau E Alemayehu S Feghali KC | 2013 | PLoS One2013，8，71： | 1 |
| 15 | Acute fatty liver in pregnancy:revealing fetal fatty acid oxidation disorders 显示文摘 | LamireauD Feghali H Redonnet-Vernhet I | 2012 | Arch Pediatr2012，19，3： | 1 |
| 16 | MAPK-activated protein kinase 2 contributes to Clostridium difficile-associated inflammation显示文摘 | Bobo L D El Feghaly R E Chen Y S | 2013 | Infect lmmun2013，81，3： | 1 |
| 17 | Spatiotemporal motion boundary detection and motion boundary velocity estimation for tracking moving objects with a moving camera: a level sets PDEs approach with concurrent camera motion compensation 显示文摘 | FEGHALI R MITICHE A | 2004 | Image Processing2004，13，11： | 1 |
| 18 | Soluble CD14 induces cytokine release by human oral epithelial cells显示文摘 | Feghali K Tanabe S Grenier D | 2011 | J Periodontal Res2011，46，1： | 1 |
| 19 | Spoit calvarial graft cranio-plasty for the prevention of headache after retrosig-moid resection of acoustic neuromas显示文摘 | Elowitz EH | 1998 | Laryngoscope1998，108，： | 1 |
| 20 | Generation of a full-length human perinatal myosin heavy-chain-encoding cDNA显示文摘 | Karsch-Mizrachi I Feghali R Shows T B | 1990 | Gene1990，89，： | 1 |
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