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您的检索式：作者名="Federico PASINI"
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| 1 | 环境许可制度:中国路径之建议显示文摘中国的环境许可立法虽有显著完善,但不改薄弱之现状。目前急需采取措施以帮助中国建立一项有效的环境许可制度。许可证在上世纪80年代后半期首次引入中国,但是在接下来的近三十年中,其主要充当排放报告制度的补充措施,而非一项污染治理政策。2014年至2015年间,中国两部环境保护和污染防治的基础法律被修订,尤其是在法律责任和公众参与方面进步明显。尽管如此,这两项法规并没有保障中国环境许可制度的有效实施。通过分析中国现行环境许可的法律和政策工具的优缺点,以及考查欧盟和美国许可制度的基本特征,本文旨在确定中国决策者为建立有效环境许可制度整体框架所应采取的重要措施。因此,在本文中,笔者认为应该制定并实施一个适应中国现状及需求的特别许可框架,并且可以从三个关键措施出发:整合现有政策工具出台专门法规;明确各级政府职责;加强企业责任追究。如果被适用,这些措施可能会大大有助于弥补中国环境许可立法的主要缺陷,从而为中国综合推行环境许可制度提供一个更加精简且兼具效率的框架。 | Federico PASINI 胡晶媚 | 2017 | 中国政法大学学报2017，，6： | 4 |
| 2 | How to select elderly colorectal cancer patients for surgery: a pilot study in an Italian academic medical center显示文摘Objective: Cancer is one of the most common diagnoses in elderly patients. Of all types of abdominal cancer, colorectal cancer(CRC) is undoubtedly the most frequent. Median age at diagnosis is approximately 70 years old worldwide. Due to the multiple comorbidities affecting elderly people, frailty evaluation is very important in order to avoid over- or undertreatment. This pilot study was designed to investigate the variables capable of predicting the long-term risk of mortality and living situation after surgery for CRC.Methods: Patients with 70 years old and older undergoing elective surgery for CRC were prospectively enrolled in the study. The patients were preoperatively screened using 11 internationally-validated-frailty-assessment tests. The endpoints of the study were long-term mortality and living situation. The data were analyzed using univariate Cox proportional-hazard regression analysis to verify the predictive value of score indices in order to identify possible risk factors.Results: Forty-six patients were studied. The median follow-up time after surgery was 4.6 years(range, 2.9-5.7 years) and no patients were lost to follow-up. The overall mortality rate was 39%. Four of the patients who survived(4/28, 14%) lost their functional autonomy. The preoperative impaired Timed Up and Go(TUG), Eastern Cooperative Group Performance Status(ECOG PS), Instrumental Activities of Daily Living(IADLs), Vulnerable Elders Survey(VES-13) scoring systems were significantly associated with increased long term mortality risk.Conclusion: Simplified frailty-assessing tools should be routinely used in elderly cancer patients before treatment in order to stratify patient risk. The TUG, ECOG-PS, IADLs and VES-13 scoring systems are potentially able to predict long-term mortality and disability. Additional studies will be needed to confirm the preliminary data in order to improve management strategies for oncogeriatric surgical patients. | Giampaolo Ugolini Francesco Pasini Federico Ghignone Davide Zattoni Maria Letizia Bacchi Reggiani Daniele Parlanti Isacco Montroni | 2015 | Cancer Biology & Medicine2015，12，4： | 4 |
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