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| 1 | Comparison between endoscopic sclerotherapy and band ligation for hemostasis of acute variceal bleeding显示文摘AIM:To compare band ligation(BL) with endoscopic sclerotherapy(SCL) in patients admitted to an emergency unit for esophageal variceal rupture. METHODS:A prospective,randomized,single-center study without crossover was conducted.After endoscopic diagnosis of esophageal variceal rupture,patients were randomized into groups for SCL or BL treatment.Sclerotherapy was performed by ethanolamine oleate intravascular injection both above and below the rupture point,with a maximum volume of 20 mL.For BL patients,banding at the rupture point was attempted,followed by ligation of all variceal tissue of the distal esophagus.Primary outcomes for both groups were initial failure of bleeding control(5 d) ,early re-bleeding(5 d to 6 wk),and complications,including mortality.From May 2005 to May 2007,100 patients with variceal bleeding were enrolled in thestudy:50 SCL and 50 BL patients.No differences between groups were observed across gender,age,ChildPugh status,presence of shock at admission,mean hemoglobin levels,and variceal size. RESULTS:No differences were found between groups for bleeding control,early re-bleeding rates,complications,or mortality.After 6 wk,36(80%) SCL and 33(77 %) EBL patients were alive and free of bleeding.A statistically significant association between Child-Pugh status and mortality was found,with 16%mortality in Child A and B patients and 84%mortality in Child C patients(P<0.001) . CONCLUSION:Despite the limited number of patients included,our results suggest that SCL and BL are equally efficient for the control of acute variceal bleeding. | Gustavo Oliveira Luz Fauze Maluf-Filho Sérgio Eiji Matuguma Fábio Yuji Hondo Edson Ide Jeane Martins Melo Spencer Cheng Paulo Sakai | 2011 | World Journal of Gastrointestinal Endoscopy2011，3，5： | 20 |
| 2 | Deep sedation during gastrointestinal endoscopy: Propofol-fentanyl and midazolam-fentanyl regimens显示文摘AIM: To compare deep sedation with propofol-fentanyl and midazolam-fentanyl regimens during upper gastrointestinal endoscopy. METHODS: After obtaining approval of the research ethics committee and informed consent, 200 patients were evaluated and referred for upper gastrointestinal endoscopy. Patients were randomized to receive propofol-fentanyl or midazolam-fentanyl (n = 100/group).We assessed the level of sedation using the observer's assessment of alertness/sedation (OAA/S) score and bispectral index (BIS). We evaluated patient and physician satisfaction, as well as the recovery time and complication rates. The statistical analysis was performed using SPSS statistical software and included the MannWhitney test, χ 2 test, measurement of analysis of variance, and the κ statistic. RESULTS: The times to induction of sedation, recovery, and discharge were shorter in the propofolfentanyl group than the midazolam-fentanyl group. According to the OAA/S score, deep sedation events occurred in 25% of the propofol-fentanyl group and 11% of the midazolam-fentanyl group (P = 0.014). Additionally, deep sedation events occurred in 19% of the propofol-fentanyl group and 7% of the midazolamfentanyl group according to the BIS scale (P = 0.039). There was good concordance between the OAA/S score and BIS for both groups (κ = 0.71 and κ = 0.63, respectively). Oxygen supplementation was required in 42% of the propofol-fentanyl group and 26% of the midazolam-fentanyl group (P = 0.025). The mean time to recovery was 28.82 and 44.13 min in the propofolfentanyl and midazolam-fentanyl groups, respectively (P < 0.001). There were no severe complications in either group. Although patients were equally satisfied with both drug combinations, physicians were more satisfied with the propofol-fentanyl combination. CONCLUSION: Deep sedation occurred with propofolfentanyl and midazolam-fentanyl, but was more frequent in the former. Recovery was faster in the propofol-fentanyl group. | Marcos Eduardo Lera dos Santos Fauze Maluf-Filho Dalton Marques Chaves Sergio Eiji Matuguma Edson Ide Gustavo de Oliveira Luz Thiago Ferreira de Souza Fernanda C Simoes Pessorrusso Eduardo Guimares Hourneaux de Moura Paulo Sakai | 2013 | World Journal of Gastroenterology2013，19，22： | 16 |
| 3 | Narrow-band imaging without magnification for detecting early esophageal squamous cell carcinoma显示文摘AIM:To compare narrow-band imaging(NBI)without image magnification,and chromoendoscopy with Lugol's solution for detecting high-grade dysplasia and intramu-cosal esophageal squamous cell carcinoma(SCC)in patients with head and neck cancer.METHODS:This was a prospective observational study of 129 patients with primary head and neck tumors consecutively referred to the Gastrointestinal Endoscopy Unit of Hospital das Clínicas,S?o Paulo University Medical School,Brazil,between August 2006 and Feb-ruary 2007.Conventional examinations with NBI and Lugol chromoendoscopy were consecutively performed,and the discovered lesions were mapped,recorded and sent for biopsy.The results of the three methods were compared regarding sensitivity,specificity,accuracy,positive predictive value,negative predictive value,positive likelihood value and negative likelihood value.RESULTS:Of the 129 patients,nine(7%)were diagnosed with SCC,5 of which were in situ and 4 which were intramucosal.All carcinomas were detected through NBI and Lugol chromoendoscopy.Only 4 lesions were diagnosed through conventional examination,all of which were larger than 10 mm.CONCLUSION:NBI technology with optical filters has high sensitivity and high negative predictive value for detecting superficial esophageal SCC,and produces results comparable to those obtained with 2.5%Lugol chromoendoscopy. | Edson Ide Fauze Maluf-Filho Dalton Marques Chaves Sergio Eiji Matuguma Paulo Sakai | 2011 | World Journal of Gastroenterology2011，17，39： | 15 |
| 4 | Endoscopic management and prevention of migrated esophageal stents显示文摘The use of self-expandable metallic stents has increased recently to palliate inoperable esophageal neoplasia and also in the management of benign strictures. Migration is one of the most common complications after stent placement and the endoscopist should be able to recognize and manage this situation. Several techniques for managing migrated stents have been described, as well as new techniques for preventing stent migration. Most stents have a 'lasso' at the upper flange which facilitates stent repositioning or removal. An overtube, endoloop and large polypectomy snare may be useful for the retrieval of stents migrated into the stomach. External fixation of the stent with Shim's technique is efficient in preventing stent migration. Suturing the stent to the esophageal wall, new stent designs with larger flanges and double-layered stents are promising techniques to prevent stent migration but they warrant validation in a larger cohort of patients. | Bruno da Costa Martins Felipe Alves Retes Bruno Frederico Medrado Marcelo Simas de Lima Caterina Maria Pia Simione Pennacchi Fabio Shiguehissa Kawaguti Adriana Vaz Safatle-Ribeiro Ricardo Sato Uemura Fauze Maluf-Filho | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，2： | 3 |
| 5 | Opinion: How to manage subepithelial lesions of the upper gastrointestinal tract?显示文摘Subepithelial lesions(SELs) in the upper gastrointestinal(GI) tract are relatively frequent findings in patients undergoing an upper GI endoscopy. These tumors, which are located below the epithelium and out of reach of conventional biopsy forceps, may pose a diagnostic challenge for the gastroenterologist, especially when SELs are indeterminate after endoscopy and endoscopic ultrasound(EUS). The decision to proceed with further investigation should take into consideration the size, location in the GI tract, and EUS features of SELs. Gastrointestinal stromal tumor(GIST) is an example of an SEL that has a well-recognized malignant potential. Unfortunately, EUS is not able to absolutely differentiate GISTs from other benign hypoechoic lesions from the fourth layer, such as leiomyomas. Therefore, EUS-guided fine needle aspiration(EUS-FNA) is an important tool for correct diagnosis of SELs. However, small lesions(size < 2 cm) have a poor diagnostic yield with EUS-FNA. Moreover, studies with EUS-core biopsy needles did not report higher rates of histologic and diagnostic yields when compared with EUS-FNA. The limited diagnostic yield of EUS-FNA and EUS-core biopsies of SELs has led to the development of more invasive endoscopic techniques for tissue acquisition. There are initial studies showing good results for tissue biopsy or resection of SELs with endoscopic submucosal dissection, suck-ligate-unroof-biopsy, and submucosal tunneling endoscopic resection. | Matheus Cavalcante Franco Ricardo Teles Schulz Fauze Maluf-Filho | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，18： | 3 |
| 6 | EUS-Guided Biliary Drainage显示文摘 | Marc Giovannini Erwan Bories Fauze Maluf-Filho | 2011 | Gastroenterology Research and Practice2011，，： | 2 |
| 7 | Long-term Outcomes of Acute Gastric Variceal Bleeding in 48 Patients Following Treatment with Cyanoacrylate显示文摘 | Petruska Marques Fauze Maluf-Filho Atul Kumar Sergio E. Matuguma Paulo Sakai Shinichi Ishioka | 2008 | Digestive Diseases and Sciences2008，，2： | 1 |
| 8 | Thermo-sensitive IPN hydrogels composed of PNIPAAm gels supported on alginateoCa^2+ with LCST tailored close to human body temperature显示文摘 | Marcia R de Moura Fauze A | 2006 | Polym Test2006，25，7： | 1 |
| 9 | Liver Retransplantation: A Model for Determining Long-Term Survival显示文摘 | Marcelo M. Linhares Daniel Azoulay Délcio Matos Adauto Castelo-Filho Tarcísio Trivi?o Alberto Goldenberg Denis Castaing René Adam Valerie Délvart Phillipe Ichai Fauze Saliba Antoine Lemoine Didier Samuel Henry Bismuth | 2006 | Transplantation2006，，7： | 1 |
| 10 | Endoscopic Detection of Early Esophageal Squamous Cell Carcinoma in Patients with Achalasia: Narrow-Band Imaging versus Lugol’s Staining显示文摘 | Edson Ide Fred Olavo Arag?o Andrade Carneiro Mariana Souza Varella Fraz?o Dalton Marques Chaves Rubens Ant?nio Aissar Sallum Eduardo Guimar?es Hourneaux de Moura Paulo Sakai Ivan Cecconello Fauze Maluf-Filho Everson L. A. Artifon | 2013 | Journal of Oncology2013，，： | 1 |
| 11 | Kras Mutation Analysis of Fine Needle Aspirate Under EUS Guidance Facilitates Risk Stratification of Patients With Pancreatic Mass显示文摘 | Fauze Maluf-Filho Atul Kumar René Gerhardt Márcia Kubrusly Paulo Sakai Fabio Hondo Sergio Eiji Matuguma Everson Artifon José Eduardo Monteiro da Cunha Marcel Cerqueira César Machado Shinichi Ishioka Elias Forero | 2007 | Journal of Clinical Gastroenterology2007，，10： | 1 |
| 12 | EUS-guided percutaneous endoscopic gastrostomy for enteral feeding tube placement显示文摘 | Dalton M. Chaves Atul Kumar Marcos E. Lera Fauze Maluf Everson L. Artifon Eduardo G. Moura Bhawna Halwan Shinichi Ishioka Paulo Sakai | 2008 | Gastrointestinal Endoscopy2008，，6： | 1 |
| 13 | A novel sampling method for the investigation of gut microbiota显示文摘AIM: In order to characterize the qualitative and quantitative microorganisms in different sites of the lower digestive tract (LDT) in healthy volunteers, a specific technique was developed for collecting mucous of the distal ileum, colon and rectum. METHODS: A polyethylene tube was designed to go through the colonoscope channel with a No. 8 French tube. In order to avoid internal contamination, the distal extremity was protected with a membrane of microfilm after being sterilized in ethilene oxid. To facilitate the aspiration of a precise volume, its interior was coated with silicone. One hundred microlliter (0.1 mL) sample of mucous was collected and transferred into an Eppenddorff tube containing nine hundred microlliter (0.9 mL) of VMGA-3 (viable medium of Goteborg). This procedure was repeated at each site of the LDT with a new sterilized catheter. RESULTS: All sites revealed the 'non pathogenic' anaerobic bacteria Veillonella sp (average 105 colony forming units/mL-CFU/mL), allowing to conclude an environment of low oxidation-reduction potential (redox) in the LDT. It was also characterized the presence of Klebisiella sp with significant statistical predominance (SSP) in the ileum. Enterobacter sp was found with SSP in the sigmoid colon, Bacteroides sp non-pigmented (npg) and E.coli with SSP in the sigmoid colon and rectum, Enterococcus sp and Lactobacillus sp with SSP in the rectum, all in a mean concentration of 105 CFU/mL. CONCLUSION: This procedure is feasible and efficient and can point out a similar distribution of the aerobic and anaerobic bacteria with the presence of biological markers of normal microbiota in the LDT. | Alina Guimares Quintanilha Bruno Zilberstein Manoel A A Santos Denis Pajecki Eduardo Guimares Hourneaux Moura Paulo Roberto Arruda Alves Fauze Maluf-Filho Ivan Cecconello | 2007 | World Journal of Gastroenterology2007，13，29： | 1 |
| 14 | Su1550 Diagnostic Yield of EUS-FNA for Upper GI Tract Subepithelial Lesions-Results of a Multicenter Study显示文摘 | Pamela Reyes Fauze Maluf-Filho Ricardo T. Schulz Livia M. Rodriguez Jimenez Leonardo Sosa Wallia J. Wever Keyur Patel Carlos Micames | 2013 | Gastrointestinal Endoscopy2013，，5： | 1 |
| 15 | Modified electrodes based on mixed bentonite vanadium(V) oxide xerogels显示文摘 | Fauze J Anaissi Gregoire J.-F Demets Henrique E Toma Antonio C.V Coelho | 1999 | Journal of Electroanalytical Chemistry1999，，1： | 1 |
| 16 | Garcin syndrome resulting from a giant cell rumor of the skull base in a child 显示文摘 | Bibas-Bonet H Fauze RA Lavado MG | 2003 | Pediatr Neurol2003，28，5： | 1 |
| 17 | Prevention of Post-ERCP Pancreatitis显示文摘 | F. Donnellan Michael F. Byrne Fauze Maluf-Filho | 2011 | Gastroenterology Research and Practice2011，，： | 1 |
| 18 | Long-term Outcomes of Acute Gastric Variceal Bleeding in 48 Patients Following Treatment with Cyanoacrylate显示文摘 | Petruska Marques Fauze Maluf-Filho Atul Kumar Sergio E. Matuguma Paulo Sakai Shinichi Ishioka | 2008 | Digestive Diseases and Sciences2008，，2： | 1 |
| 19 | Long-term Outcomes of Acute Gastric Variceal Bleeding in 48 Patients Following Treatment with Cyanoacrylate显示文摘 | Petruska Marques Fauze Maluf-Filho Atul Kumar Sergio E. Matuguma Paulo Sakai Shinichi Ishioka | 2008 | Digestive Diseases and Sciences2008，，2： | 1 |
| 20 | Long-term Outcomes of Acute Gastric Variceal Bleeding in 48 Patients Following Treatment with Cyanoacrylate显示文摘 | Petruska Marques Fauze Maluf-Filho Atul Kumar Sergio E. Matuguma Paulo Sakai Shinichi Ishioka | 2008 | Digestive Diseases and Sciences2008，，2： | 1 |
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