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| 1 | Single vs dual(en bloc) kidney transplants from donors ≤ 5 years of age: A single center experience显示文摘AIM: To compare outcomes between single and dual en bloc(EB) kidney transplants(KT) from small pediatric donors. METHODS: Monocentric nonprospective review of KTs from pediatric donors ≤ 5 years of age. Dual EB KT was defined as keeping both donor kidneys attached tothe inferior vena cava and aorta, which were then used as venous and arterial conduits for the subsequent transplant into a single recipient. Donor age was less useful than either donor weight or kidney size in decision-making for kidney utilization as kidneys from donors < 8 kg or kidneys < 6 cm in length were not transplanted. Post-transplant management strategies were standardized in all patients.RESULTS: From 2002-2015, 59 KTs were performed including 34 dual EB and 25 single KTs. Mean age of donors(17 mo vs 38 mo, P < 0.001), mean weight(11.0 kg vs 17.4 kg, P = 0.046) and male donors(50% vs 84%, P = 0.01) were lower in the dual EB compared to the single KT group, respectively. Mean cold ischemia time(21 h), kidney donor profile index(KDPI; 73% vs 62%) and levels of serum creatinine(SCr, 0.37 mg/d L vs 0.49 mg/d L, all P = NS) were comparable in the dual EB and single KT groups, respectively. Actuarial graft and patient survival rates at 5-years follow-up were comparable. There was one case of thrombosis resulting in graft loss in each group. Delayed graft function incidence(12% dual EB vs 20% single KT, P = NS) was slightly lower in dual EB KT recipients. Initial duration of hospital stay(mean 5.4 d vs 5.6 d) and the one-year incidences of acute rejection(6% vs 16%), operative complications(3% vs 4%), and major infection were comparable in the dual EB and single KT groups, respectively(all P = NS). Mean 12 mo SCr and abbreviated MDRD levels were 1.17 mg/d L vs 1.35 mg/d L and 72.5 m L/min per 1.73 m^2 vs 60.5 m L/min per 1.73 m^2(both P = NS) in the dual EB and single KT groups, respectively. CONCLUSION: By transplanting kidneys from young pediatric donors into adult recipients, one can effectively expand the limited donor pool and achieve excellent medium-term outcomes. | Yousef Al-Shraideh Umar Farooq Hany El-Hennawy Alan C Farney Amudha Palanisamy Jeffrey Rogers Giuseppe Orlando Muhammad Khan Amber Reeves-Daniel William Doares Scott Kaczmorski Michael D Gautreaux Samy S Iskandar Gloria Hairston Elizabeth Brim Margaret Mangus Robert J Stratta | 2016 | World Journal of Transplantation2016，6，1： | 3 |
| 2 | Adaptive servoventilation (ASV) in patients with sleep disordered breathing associated with chronic opioid medications for non-malignant pain显示文摘 | Farney RJ Walker JM Boyle KM | 2008 | J Clin Sleep Med2008，4，： | 1 |
| 3 | Successful unin- tentional ABO-incompatible renal transplantation: Blood group A1B donor into an A2B recipient显示文摘 | Fadeyi EA Stratta R J Farney AC | 2014 | Am J Clin Pathol2014，141，5： | 1 |
| 4 | Kidney transplantation from donation after cardiac death donors:lack of impact of delayed graft function on post-transplant outcomes显示文摘 | Singh RP Farney AC Rogers J | | 0，，02： | 1 |
| 5 | Click analytics:Visualizing website use data显示文摘 | Farney T A | | 0，，： | 1 |
| 6 | Experience in re- nal and extrarenal transplantation with donation after cardiac death donors with selective use of extracorporeal support显示文摘 | Farney AC Singh RP HinesMH | 2008 | J Am Coll Surg2008，206，5： | 1 |
| 7 | Evolving experienceusing kidneys from deceased donors with terminal acute kidneyinjury显示文摘 | Farney AC Rogers J Orlando G | 2013 | J Am Coll Surg2013，216，4： | 1 |
| 8 | Treatment options for re- nal cell carcinoma in renal allografts : a case series from a single in- stitution 显示文摘 | Swords DC A1-Geizawi SM Farney AC | 2013 | Clin Transplant2013，27，2： | 1 |
| 9 | Influence ofpulsatile perfusion preservation on outcomes in kidneytransplantation from expanded criteria donors显示文摘 | Stratta RJ Moore PS Farney AC | 2007 | J Am CollSurg2007，204，5： | 1 |
| 10 | Evolution of islet transplantation for the last 30 years 显示文摘 | Farney AC Sutherland DE Opara EC | 2016 | Pancreas2016，45，1： | 1 |
| 11 | Simultaneous use of antidepressant and antihypertensive medications increases likelihood of diagnosis of obstructive sleep apnea syndrome显示文摘 | Farney RJ Lugo A Jensen RL | 2004 | Chest2004，125，4： | 1 |
| 12 | Evolving experience using kidneys from deceased donors with terminal acute kidney injury显示文摘 | Farney AC Rogers J Orlando G | 2013 | J Am Coil Surg2013，216，4： | 1 |
| 13 | Experience in Renal and Extrarenal Transplantation with Donation after Cardiac Death Donors with Selective Use of Extracorporeal Support 显示文摘 | Farney AC Singh RP Hines MH | 2008 | J Am Coil Sure2008，206，5： | 1 |
| 14 | Pancreas transplantation:the histologic morphology of graft loss and clinical correlations显示文摘 | Drachenberg CB Papadimitiou JC Farney A | 2001 | Transplantation2001，71，12： | 1 |
| 15 | Improved islet isolation from rat pancreas using 35 % bovine serum albumin in combination with dextran gradient separation显示文摘 | Field J Farney A Sutherland E R D | 1996 | Transplantation1996，61，10： | 1 |
| 16 | Single center experience transplanting kidneys from deceased donors with terminal acute renal failure显示文摘 | ZuckermanJM Singh RP Farney AC | 2009 | Surgery2009，146，4： | 1 |
| 17 | Evolution of kidney, pancreas, and islet transplantation for patients with diabetes at the University of Minnesota显示文摘 | Sutherland DE Gores PF Farney AC | 1993 | Am J Surg1993，166，5： | 1 |
| 18 | Analysis of bacteremia after pancreatic transplantation with enteric drainage显示文摘 | Singh RP Farney AC Rogers J | 2008 | Transplant Proc2008，40，： | 1 |
| 19 | Superiority of portal venous drainage over systemic venous drainage in pancreas transplantation: a retrospective study 显示文摘 | Philosophe B Farney AC Schweitzer EJ | 2001 | Ann Surg2001，234，6： | 1 |
| 20 | Experience in renal and extrarenal transplantation with donation after cardiac death donors with selective use of extracorporeal support显示文摘 | Farney AC Singh RP Hines MH | 2008 | J Am Coll Surg2008，206，10： | 1 |
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