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| 1 | Taurine Transporter dEAAT2 is Required for Auditory Transduction in Drosophila显示文摘Drosophila dEAAT2, a member of the excitatory amino-acid transporter(EAAT) family, has been described as mediating the high-affinity transport of taurine, which is a free amino-acid abundant in both insects and mammals. However, the role of taurine and its transporter in hearing is not clear. Here, we report that dEAAT2 is required for the larval startle response to sound stimuli. d EAAT2 was found to be enriched in the distal region of chordotonal neurons where sound transduction occurs. The Ca^(2+) imaging and electrophysiological results showed that disrupted dEAAT2 expression significantly reduced the response of chordotonal neurons to sound.More importantly, expressing d EAAT2 in the chordotonal neurons rescued these mutant phenotypes. Taken together,these findings indicate a critical role for Drosophila dEAAT2 in sound transduction by chordotonal neurons. | Ying Sun Yanyan Jia Yifeng Guo Fangyi Chen Zhiqiang Yan | 2018 | Neuroscience Bulletin2018,34,6: | 4 |
| 2 | Synthesis of size-controlled CoMn2O4 quantum dots supported on carbon nanotubes for electrocatalytic oxygen reduction/evolution显示文摘 | Jiajia Shi Kaixiang Lei Weiyi Sun Fujun Li Fangyi Cheng Jun Chen | 2017 | Nano Research2017,10,11: | 3 |
| 3 | Rapid low-temperature synthesis of perovskite/carbon nanocomposites as superior electrocatalysts for oxygen reduction in Zn-air batteries显示文摘 | Zhenhua Yan Hongming Sun Xiang Chen Xiaorui Fu Chengcheng Chen Fangyi Cheng Jun Chen | 2018 | Nano Research2018,11,6: | 2 |
| 4 | Behavioral methods for the functional assessment of hair cells in zebrafish显示文摘Zebrafish 是为听觉的系统上的研究的一个新兴的动物模型。这个模型与人,到听见的机关的好可接近性,和高产量能力介绍高相似性。为了更好利用这个动物模型,,方法论需要被用来听力确定 zebrafish 的功能。Zebrafish 显示与它的听觉的功能有关的一系列天生、柔韧的行为。这里,我们考察了在听觉的研究使用 zebrafish 的优点然后如下介绍了三行为的测试:startle 反应,门厅眼睛的反射,和走流性。这些测试以他们的生理的特征,新技术发展,和仪器描述被讨论。测试限制和区域也被介绍改善。最后,我们在 zebrafish 揭示了这些应用的可行性在在听觉相关的基因和药上的高产量的屏蔽的行为的评价和他们的潜力。 | Qin Yang Peng sun Shi Chen Hongzhe Li Fangyi Chen | 2017 | Frontiers of Medicine2017,11,2: | 1 |
| 5 | A Study of Histology and Enzymatic Histochemistry on Rabbit's Retina in Acute Ocular Hypertension显示文摘The changes of activities of enzymes relating to energy metabolism in rabbit's retina in acute ocular hypertension were observed. The activities of succinate dehydrogenase and adenosine triphosphatase were found to be reduced, while the activities of the lactatic dehydrognease and glucose-6-phosphatase increased. The results revealed the metabolic disturbance of energy in retina after acute ocular hypertension might be the underlying factors relating to the defects of the functions and structures of the... | Weirong Sun, Shumei Wang, Guiqiu Zhao, Jianlu Gao, Fangyi LiuThe Department of Ophthalmology, The Affilliated Hospital of Qingdao Medical College Qingdao 266003, China | 1994 | 眼科学报1994,10,3: | 1 |
| 6 | Polaron interfacial entropy as a route to high ther moelectric perfor mance in DAE-doped PEDOT:PSS films显示文摘Enhancing the thermoelectric transport properties of conductive polymer materials has been a long-term challenge,in spite of the success seen with molecular doping strategies.However,the strong coupling between the thermopower and the electrical conductivity limits thermoelectric performance.Here,we use polaron interfacial occupied entropy engineering to break through this intercoupling for a PEDOT:PSS(poly(3,4-ethylenedioxythiophene)-poly(4-styrenesulfonate))thin film by using photochromic diarylethene(DAE)dopants coupled with UV-light modulation.With a 10-fold enhancement of the thermopower from 13.5μV K^(-1) to 135.4μV K^(-1) and almost unchanged electrical conductivity,the DAE-doped PEDOT:PSS thin film achieved an extremely high power factor of 521.28μW m^(-1) K^(-2) from an original value of 6.78μW m^(-1) K^(-2).The thermopower was positively correlated with the UV-light intensity but decreased with increasing temperature,indicating resonant coupling between the planar closed DAE molecule and PEDOT.Both the experiments and theoretical calculations consistently confirmed the formation of an interface state due to this resonant coupling.Interfacial entropy engineering of polarons could play a critical role in enhancing the thermoelectric performance of the organic film. | Jiajia Zhang Caichao Ye Genwang Wei Liang Guo Yuhang Cai Zhi Li Xinzhi Wu Fangyi Sun Qikai Li Yupeng Wang Huan Li Yuchen Li Shuaihua Wang Wei Xu Xuefeng Guo Wenqing Zhang Weishu Liu | 2024 | National Science Review2024,11,3: | 0 |
| 7 | From imines to amides via NHC-mediated oxidation显示文摘The unprecedented NHC-mediated oxidation of imines to amides is described.This protocol features broad substrate scope and allows rapid assembly of amides in good to high yields.Notably,this process includes not only the umpolung of imines,but also the discovery of NHC-bound 1,2-dioxetane intermediates. | Shaofa Sun Donghui Guo Fangyi Li Jian Wang | 2022 | Organic Chemistry Frontiers2022,9,2: | 0 |
| 8 | Porous 3D carbon-based materials:An emerging platform for efficient hydrogen production显示文摘Due to their unique properties and uninterrupted breakthrough in a myriad of clean energy-related applications,carbon-based materials have received great interest.However,the low selectivity and poor conductivity are two primary difficulties of traditional carbon-based materials(zero-dimensional(0D)/one-dimensional(1D)/two-dimensional(2D)),enerating inefficient hydrogen production and impeding the future commercialization of carbon-based materials.To improve hydrogen production,attempts are made to enlarge the surface area of porous three-dimensional(3D)carbon-based materials,achieve uniform interconnected porous channels,and enhance their stability,especially under extreme conditions.In this review,the structural advantages and performance improvements of porous carbon nanotubes(CNTs),g-C_(3)N_(4),covalent organic frameworks(COFs),metal-organic frameworks(MOFs),MXenes,and biomass-derived carbon-based materials are firstly summarized,followed by discussing the mechanisms involved and assessing the performance of the main hydrogen production methods.These include,for example,photo/electrocatalytic hydrogen production,release from methanolysis of sodium borohydride,methane decomposition,and pyrolysis-gasification.The role that the active sites of porous carbon-based materials play in promoting charge transport,and enhancing electrical conductivity and stability,in a hydrogen production process is discussed.The current challenges and future directions are also discussed to provide guidelines for the development of next-generation high-efficiency hydrogen 3D porous carbon-based materials prospected. | Fangyi Li Jizhou Jiang Jiamei Wang Jing Zou Wei Sun Haitao Wang Kun Xiang Pingxiu Wu Jyh-Ping Hsu | 2023 | Nano Research2023,16,1: | 0 |