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| 1 | Impact of laparoscopic surgery training laboratory on surgeon's performance显示文摘Minimally invasive surgery has been replacing the open standard technique in several procedures. Similar or even better postoperative outcomes have been described in laparoscopic or robot-assisted procedures when compared to open surgery. Moreover, minimally invasive surgery has been providing less postoperative pain, shorter hospitalization, and thus a faster return to daily activities. However, the learning curve required to obtain laparoscopic expertise has been a barrier in laparoscopic spreading. Laparoscopic surgery training laboratory has been developed to aid surgeons to overcome the challenging learning curve. It may include tutorials, inanimate model skills training(box models and virtual reality simulators), animal laboratory, and operating room observation. Several different laparoscopic courses are available with specific characteristics and goals. Herein, we aim to describe the activities performed in a dry and animal-model training laboratory and to evaluate the impact of different kinds of laparoscopic surgery training courses on surgeon's performance. Several tasks are performed in dry and animal laboratory to reproduce a real surgery. A short period of training can improve laparoscopic surgical skills, although most of times it is not enough to confer laparoscopic expertise for participants. Nevertheless, this short period of training is able to increase the laparoscopic practice of surgeons in their communities. Full laparoscopic training in medical residence or fellowship programs is the best way of stimulating laparoscopic dissemination. | Fabio C M Torricelli Joao Arthur B A Barbosa Giovanni S Marchini | 2016 | World Journal of Gastrointestinal Surgery2016，8，11： | 6 |
| 2 | Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring显示文摘现在有充分证据,对在使肥沃的后代显型的父亲的贡献多于公平 DNA。然而,这 nongenetic 继承的身份和机制糟糕被理解。在这个研究区域的更重要的问题之一是:在精子 DNA methylation 的变化为后代有 phenotypic 后果吗?我们以前报导了肥胖的雄的老鼠的后代与控制相比改变了葡萄糖新陈代谢并且这效果通过 nongenetic 工具被继承。这里,我们用一样的协议在一个新队描述调查进精子 DNA methylation。在高脂肪的节食的雄的老鼠是 30% 比喂控制的男性重在交配的时候(16-19 星期旧, n = 14/14 ) 。一小(0.25%) 在全部的 5-methyl-2 ’ 增加; -deoxycytidine 被液体层析双人脚踏车团 spectrometry 在肥胖的老鼠精子检测。那 retrotransposon DNA methylation 在精子说的有定序的充实蛋白质的染色体(MBD-Seq ) 和 pyrosequencing 揭示了的 methyl-CpG 绑定领域的染色体的重复部分的检查没被肥胖,而是 methylation 在整个染色体在卫星重复影响被增加。然而,从男 27-week-old 后代从的肌肉,肝,和精子的检查肥胖并且控制父亲(从 8 生的 n = 的两个组) 表明正常 DNA methylation 层次在后代开发期间被恢复。而且,没有变化在肥胖的老鼠精子在三个 genomic 印记被发现。我们的调查结果为 transgenerational epigenetic reprogramming 有含意。他们建议 postfertilization 机制为使导致 environmentally 的 DNA methylation 在精子房间改变的一些正常化存在。 | Neil A Youngson Virginie Lecomte Christopher A Maloney Preston Leung Jia Liu Luke B Hesson Fabio Luciani Lutz Krause Margaret J Morris | 2016 | Asian Journal of Andrology2016，18，6： | 3 |
| 3 | Worldwide trends in gastric cancer mortality (1980–2011), with predictions to 2015, and incidence by subtype显示文摘 | Ana Ferro Bárbara Peleteiro Matteo Malvezzi Cristina Bosetti Paola Bertuccio Fabio Levi Eva Negri Carlo La Vecchia Nuno Lunet | 2014 | European Journal of Cancer2014，，： | 3 |
| 4 | Acute fatty liver of pregnancy associated with severe acute pancreatitis:A case report显示文摘Acute fatty liver of pregnancy is a rare disease that affects women in the third trimester of pregnancy. Although infrequent, the disease can cause maternal mortality. The diagnosis is not always clear until the pregnancy is terminated, and significant complications, such as acute pancreatitis, can occur. Pancreatic involvement typically only occurs in severe cases after the development of hepatic and renal impairment. To date, little knowledge is available regarding how the disease causes pancreatitis. Treatment involves supportive measures and pregnancy interruption. In this report, we describe a case of a previously healthy 26-year-old woman at a gestational age of 27 wk and 6 d who was admitted with severe abdominal pain and vomiting. This case illustrates the clinical and laboratory overlap between acute fatty liver of pregnancy and pancreatitis, highlighting the difficulties in differentiating each disease. Furthermore, the hypothesis for this overlapping is presented, and the therapeutic options are discussed. | Cássio Vieira de Oliveira Alecsro Moreira Julio P Baima Leticia de C Franzoni Talles B Lima Fabio da S Yamashiro Kunie Yabuki Rabelo Coelho Ligia Y Sassaki Carlos Antonio Caramori Ferno G Romeiro Giovanni F Silva | 2014 | World Journal of Hepatology2014，6，7： | 3 |
| 5 | Characterization and clinical impact of antinuclear antibodies in primary biliary cirrhosis显示文摘 | Paolo Muratori Luigi Muratori Rodolfo Ferrari Fabio Cassani Giampaolo Bianchi Marco Lenzi Luis Rodrigo Antonio Linares Dolores Fuentes Francesco B Bianchi | 2003 | The American Journal of Gastroenterology2003，，2： | 2 |
| 6 | Straightforward synthesis of new tetrahydroquinoline derivatives 显示文摘 | Di Fabio R Alvaro G Bertani B | 2000 | Canadian Journal of Chemistry2000，78，6： | 1 |
| 7 | Carbon/carbon-boron nitride composites with improved wear resisitance compared to carbon/carbon 显示文摘 | Seghi S Fabio B Economy J | 2004 | Carbon2004，42，： | 1 |
| 8 | Color Doppler imaging of posttraumatic priapism before and after selective em- bolizationl显示文摘 | MICHELE B EMILIO Q FABIO PM | 2003 | Radio Graphics2003，23，： | 1 |
| 9 | Carbon/carbon-boron nitride composites with improved wear resistance compared to carbon/carbon 显示文摘 | SEGHI S FABIO B ECONOMY J | 2004 | Carbon2004，42，： | 1 |
| 10 | Effect of substrate grain size and surface treatments on the cutting properties of diamond coated co-cemented tungsten carbide tools显示文摘 | Riccardo P Fabio B Fabrizio C | 2002 | Diamond and Related Materials2002，11，： | 1 |
| 11 | A fractal-based algorithm for detecting first arrivals on seismic traces显示文摘 | Mike D D Ron D L | 1993 | Geophysics1993，61，4： | 1 |
| 12 | Pelvic and paraortic lymph nodal status in advanced ovarian cancer and survival显示文摘 | FABIO F P GIORGIO B PAOLO G | 1999 | Gynecol Oncol1999，74，： | 1 |
| 13 | Position control for active secondary mirror of a two-mirror telescope显示文摘 | CLAUDIO P FABIO B KLAUS R | 1997 | SPIE1997，3111，： | 1 |
| 14 | Real-time planner in the operational space for the automatic handling of kinematic constraints显示文摘 | Corrado G Lo B Fabio G | 2014 | IEEE Transactions on Automation Science and Engineering2014，3，11： | 1 |
| 15 | Spontaneous Polarization and Piezoelectric Constants of III-V Nitrides显示文摘 | Fabio B Vincenzo F | 1997 | Physical Review B1997，56，16： | 1 |
| 16 | Normal phase liquid chromatography-electrospray ionization tandem mass spectrometry analysis of phospholipid molecular species in blood mononuclear cells : application to cystic fibrosis 显示文摘 | MARCO M FABIO B EMANUELE B | 2004 | Journal of Chromatography B2004，810，： | 1 |
| 17 | Baffling system for the Wide Angle Camera (WAC) of ROSETTA mission显示文摘 | PIERFRANCESCO B FABIO P | 2000 | SPIE2000，4093，： | 1 |
| 18 | Nerve Growth Factor and Its High-Affinity Receptor in Chronic Pancreatitis显示文摘 | Helmut Friess Zhao-Wen Zhu Fabio F. di Mola Christoph Kulli Hans U. Graber ?ke Andren-Sandberg Arthur Zimmermann Murray Korc Max Reinshagen Markus W. Büchler | 1999 | Annals of Surgery1999，，5： | 1 |
| 19 | Development and testing of a 10 kA hybrid mechanical - static DC circuit breaker 显示文摘 | Luca N Fabio B Alberto F | 2011 | IEEE Transactions on Applied Superconductivity2011，21，6： | 1 |
| 20 | Effect of soy-derived isoflavones hot flushes,endometrial thickness,and the pulsatility index of the uterine and cerebral arteries显示文摘 | Fabio E Modena A B | 2003 | Fertil Steril2003，79，： | 1 |
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