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| 1 | Cervical inlet patch-optical coherence tomography imaging and clinical significance显示文摘AIM:To demonstrate the feasibility of optical coherence tomography(OCT)imaging in differentiating cervical inlet patch(CIP)from normal esophagus,Barrett'sesophagus(BE),normal stomach and duodenum. METHODS:This study was conducted at the Veterans Affairs Boston Healthcare System(VABHS).Patients undergoing standard esophagogastroduodenoscopy at VABHS,including one patient with CIP,one representative patient with BE and three representative normal subjects were included.White light video endoscopy was performed and endoscopic 3D-OCT images were obtained in each patient using a prototype OCT system.The OCT imaging probe passes through the working channel of the endoscope to enable simultaneous video endoscopy and 3D-OCT examination of the human gastrointestinal(GI)tract.Standard hematoxylin and eosin(H and E)histology was performed on biopsy or endoscopic mucosal resection specimens in order to compare and validate the 3D-OCT data. RESULTS:CIP was observed from a 68-year old male with gastroesophageal reflux disease.The CIP region appeared as a pink circular lesion in the upper esophagus under white light endoscopy.OCT imaging over the CIP region showed columnar epithelium structure,which clearly contrasted the squamous epithelium structure from adjacent normal esophagus.3D-OCT images obtained from other representative patients demonstrated distinctive patterns of the normal esophagus,BE,normal stomach,and normal duodenum bulb.Microstructures,such as squamous epithelium,lamina propria, muscularis mucosa,muscularis propria,esophageal glands,Barrett's glands,gastric mucosa,gastric glands, and intestinal mucosal villi were clearly observed with OCT and matched with H and E histology.These results demonstrated the feasibility of using OCT to evaluate GI tissue morphology in situ and in real-time. CONCLUSION:We demonstrate in situ evaluation of CIP microstructures using 3D-OCT,which may be a useful tool for future diagnosis and follow-up of patients with CIP. | Chao Zhou Tejas Kirtane Tsung-Han Tsai Hsiang-Chieh Lee Desmond C Adler Joseph M Schmitt Qin Huang James G Fujimoto Hiroshi Mashimo | 2012 | World Journal of Gastroenterology2012，18，20： | 3 |
| 2 | 显示文摘 | FUJIMOTO C KINO J SAWADA H | 1995 | J Chromatogr: A1995，716，12： | 1 |
| 3 | Quantitative analyses of biochemical kinetic resolutions of enantiomers显示文摘 | Chen C S Fujimoto Y Girdaukas G | 1982 | J Am Chem Soc1982，104，： | 1 |
| 4 | Treatment of uterine fibroid tumoar in a nudemonse model using high-intensity focused ultrasound显示文摘 | Vaezy S Fujimoto V Y Walker C | 2000 | American Journal of Obstetrics and Gynecologyl2000，183，1： | 1 |
| 5 | White - matter injury is associated with impaired gaze in prerrLature infants 显示文摘 | Glass HC Fujimoto S Ceppi - Cozzio C | 2008 | Pediatr Neurol2008，38，1： | 1 |
| 6 | Treatment of u- terine fibroid tumors in a nude mouse model using high inten- sity focused ultrasound 显示文摘 | Vazey S Fujimoto V Y Walker C | 2000 | Am J Obstet Gynecol2000，183，： | 1 |
| 7 | Synthesis and structure of inorganic and organometallic N, N'-bis (3,5-di-tert-butylsalicylidene) ethylenediamine yttrium complexes显示文摘 | Evans W J Fujimoto C H Ziller J W | 2002 | Polyhedron2002，21，12： | 1 |
| 8 | Fatty acid 9-and 13-hydroperoxide lyases from cucumber显示文摘 | Matsui K Ujita C Fujimoto S | 2000 | FEBS Letter2000，481，： | 1 |
| 9 | Efficient Execution of Time Warp Programs on Heterogeneous, NOWPlatforms显示文摘 | C D Carothers R M Fujimoto | 2000 | IEEE Trans on Parallel and Distributed Systems2000，11，3： | 1 |
| 10 | Calcium oscillation linked to pacemaking of interstitial cells of Cajal : requirement of calcium influx and localization of TRP4 in caveolae 显示文摘 | Torihashi S Fujimoto T Trost C | 2002 | J Biol Chem2002，277，19： | 1 |
| 11 | Treatment of uterine fibroid tumors in a nude mouse modelusing high intensity focused ulterasound显示文摘 | Vaezy S Fujimoto V Y Walker C | 2000 | AM J Obstet Gynecol2000，183，： | 1 |
| 12 | In vivo Retinal Imaging by Optical Coherence Tomography显示文摘 | SCHUMAN E A PULIAFITO C A FUJIMOTO J G | 1993 | Opt Lett1993，18，4： | 1 |
| 13 | Quantitative Analyses of Biochemical Kinetic Resolutions of Enantiomers显示文摘 | Chen C S Fujimoto Y Girdaukas G | 1982 | J Am Chem Soc1982，104，25： | 1 |
| 14 | Treatment of uterine fibroid tumors in a nude mouse modei using high- intensity focused ultrasound 显示文摘 | Vaezy S Fujimoto VY Walker C | 2000 | American Journal of Obstetrics and Gynecology2000，183，1： | 1 |
| 15 | Detection of periodontal pathogen Porphyromonas gingivalis by loop-mediated isothermal amplification method显示文摘 | Kokeguchib S Fujimoto C | 2005 | FEMS Immunology and Medical Microbiology2005，43，2： | 1 |
| 16 | Detection of periodontal pathogen porphyromonas gingivalis by loop-mediated isothermal amplification显示文摘 | Maeda H Kokeguchi S Fujimoto C | 2005 | FEMS Immunology and Medical Microbiology2005，43，： | 1 |
| 17 | Treatment of u- terine fibroid tumors in a nude mouse model using high intensity focused ultrasound显示文摘 | Vaezy S Fujimoto VY Walker C | 2000 | Am J Obstet Gynecol2000，183，1： | 1 |
| 18 | Tocilizumab is effective for pulmonary hypertension associated with multicentric Castleman's disease显示文摘 | Taniguchi K Shimazaki C Fujimoto Y | 2009 | Int J Hematol2009，90，1： | 1 |
| 19 | Practical implementation of ultra-wide band partial discharge detectors显示文摘 | Stone G C Sedding H G Fujimoto N | 1992 | IEEE Trans on Electrical Insulation1992，27，1： | 1 |
| 20 | Detection of periodontalpathogen Porphyromonas gingivalis by loop-mediated isothermalamplification method显示文摘 | Maeda H Kokeguchi S Fujimoto C | 2005 | FEMS Immunology & MedicalMicrobiology2005，43，2： | 1 |
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