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| 1 | Family presence and environmental factors at the time of a patient's death in an ICU显示文摘 | Fridh I Forsberg A Bergbom I | | 0，，： | 1 |
| 2 | Technology transfer in United States universities: A survey and statistical analysis显示文摘 | Carlsson B Fridh A | 2002 | Journal of Evolutionary Economics2002，12，2： | 1 |
| 3 | Technology Transfer in United States Universities,A Survey and Statistical analysis显示文摘 | Bo Carlsson Ann-Charlotte Fridh | 2002 | Journal of Evolutionary Economics2002，，12： | 1 |
| 4 | Technology Transfer in United States University A Survey and Statistical Analysis显示文摘 | CARLSSON B FRIDH A C | | 0，，12： | 1 |
| 5 | Calculating CO2 uptake for existing concrete structures during and aider service life 显示文摘 | Andersson R Fridh K Stripple H | 2013 | Environmental science and technology2013，47，11： | 1 |
| 6 | Using mode and maximum values from the Numeric Rating Scale when evaluating postoperative pain management and recovery显示文摘 | Kerstin Eriksson Lotta Wikstr?m Marianne Lindblad‐Fridh Anders Brostr?m | 2012 | Journal of Clinical Nursing . 2012 (5-6)2012，，5： | 1 |
| 7 | A test method to assess the frost resistance of concrete at the waterline of hydraulic structures显示文摘 | ROSENQVIST M OXFALL M FRIDH K | 2014 | Materials and Structures2014，47，3： | 1 |
| 8 | Factors associated with more intense labor pain显示文摘 | Fridh G Kopare T Gaston-Johansson L | 1988 | Research in Nursing and Health1988，11，4： | 1 |
| 9 | Factors associated with more intense labor pain显示文摘 | Fridh G Kopare T Gastorr J L | 1988 | Research in Nursing and Health1988，11，4： | 1 |
| 10 | Technology transfer in United States universities:a survey and statistical analysis显示文摘 | CARLSSON B FRIDH A | 2002 | Journal of evolutionary economics2002，12，2： | 1 |
| 11 | Technology Transfer in United States Universities: A Survey and Statistical Analysis显示文摘 | CARI-SSON B FRIDH A C | 2002 | Jounal of Ev- olutionary Economics2002，12，12： | 1 |
| 12 | Technology Transfer in United States University a Survey and Statistical Analysis 显示文摘 | Bo Carlsson Ann-Charlotte Fridh | 2002 | Evolutionary Economics2002，，12： | 1 |
| 13 | Increased induced experimental pancreatitis显示文摘 | Hiithofer K Gastillo CFD Fridh TW | 1995 | Ann Surg1995，211，： | 1 |
| 14 | Technology transfer in united states universities: a survey and statistical analysis 显示文摘 | Carlsson B Fridh A C | 2002 | Journal of Evolutionary Economics2002，12，12： | 1 |
| 15 | Unsteady forces of rotor blades in full and partial admission turbines显示文摘 | Hushmandi N B Fridh J E Fransson T H | 2011 | Journal of Turbomachinery2011，133，04： | 1 |
| 16 | Technology Transfer in United States Universities: A Survey and Statistical Analysis 显示文摘 | Bo Carlsson Ann-Charlotte Fridh | 2002 | Journal of Evolutionary Economics2002，，12： | 1 |
| 17 | Technology transfer in United States Universities: A survey and statistical analysis 显示文摘 | CARISSON B FRIDH A | 2002 | Journal of Evolution- ary Economics2002，12，： | 1 |
| 18 | Special issue: Technology transfer in United States universities 显示文摘 | Fridh C A Carlsson B | 2002 | Journal of Evolutionary Economics2002，12，1： | 1 |
| 19 | Technology transfer in United States universities 显示文摘 | Carlsson B Fridh A C | 2002 | Journal of Evolutionary Economics2002，12，12： | 1 |
| 20 | Surrogate potency assays:Comparison of binding profiles complements dose response curves for unambiguous assessment of relative potencies显示文摘Surface plasmon resonance(SPR) systems are widely used for detailed characterization of antibody activities including antigen and Fc-receptor binding. During the later stages of development, where the focus is to ensure that established critical quality attributes(CQAs) are maintained during cell culture,purification and formulation processes, analysis is simplified, and relative potencies are often determined. Here, simulation of binding data revealed that relative potency values, determined via parallel line analysis(PLA) and half maximal effective concentration(EC50) analysis accurately reflect changes in active concentration only if binding kinetics remain unchanged. Changes in the association rate constant shifted dose response curves, and therefore relative potencies, in the same way as changes in analyte concentration do. However, for interactions characterized by stable binding, changes in the dissociation rate constant did not result in any shift, suggesting that this type of change may go unnoticed in the dose response curve. Thus, EC50 and PLA analyses of dose response curves obtained with an anti-TNF-α antibody were complemented with the Biacore functionality for sensorgram comparison analysis, whereby changes in antigen and Fc-receptor binding profiles could be detected. Next, analysis of temperature stressed TNF-α antibody revealed that calibration free concentration analysis(CFCA) data correlated perfectly with relative potency values. Together, these results demonstrate that combinations of SPR based dose response curves, sensorgram comparison and CFCA can be used to strengthen the confidence in relative potency assessments, and suggest that SPR can potentially be used as a surrogate potency assay in the quality control of biotherapeutic medicines. | Robert Karlsson Veronica Fridh Asa Frostell | 2018 | Journal of Pharmaceutical Analysis2018，8，2： | 0 |
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