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| 1 | Machine learning assisted design of γ′-strengthened Co-base superalloys with multi-performance optimization显示文摘Designing a material with multiple desired properties is a great challenge,especially in a complex material system.Here,we propose a material design strategy to simultaneously optimize multiple targeted properties of multi-component Co-base superalloys via machine learning.The microstructural stability,γ′solvus temperature,γ′volume fraction,density,processing window,freezing range,and oxidation resistance were simultaneously optimized. | Pei Liu Haiyou Huang Stoichko Antonov Cheng Wen Dezhen Xue Houwen Chen Longfei Li Qiang Feng Toshihiro Omori Yanjing Su | 2020 | npj Computational Materials2020,,1: | 8 |
| 2 | Polydopamine and ammonium bicarbonate coated and doxorubicin loaded hollow cerium oxide nanoparticles for synergistic tumor therapy显示文摘The development of effective nanoplatforms is extremely necessary for cancer therapy.Herein,we prepared polydopamine(PDA)andammonium bicarbonate(NH4HCO3)coated and doxorubicin(Dox)loaded hollow cerium oxide(CeO2)NPs(PDAC NPs),which showedexcellent synergistic effect for photothermal therapy,chemotherapy and chemodynamic therapy.Under near infrared laser irradiation,PDA shell could absorb the incident light and convert it into heat,which could not only kill tumor cells with hyperthermia,but also trigger thedecomposition of NH4HCO3 into gaseous carbon dioxide and ammonia,leading to the destroy of PDA shell.The leakage of PDA furtheraccelerated Dox release and exposed CeO2 surface,in which Dox could enter into cell nucleus to induce chemotherapy,and CeO2 couldcatalyze cellular hydrogen peroxide into hydroxyl radical to present chemodynamic therapy.In fact,PDAC NPs showed an excellenttherapeutic efficacy both in vitro and in vivo.This design provides a new strategy for synergistic tumor therapy. | Keqiang Xu Yan Cheng Jiao Yan Yanlin Feng Runxiao Zheng Xiaqhig Wu Yanjing Wang Panpan Song Haiyuan Zhang | 2019 | Nano Research2019,12,12: | 4 |
| 3 | A Vision of Materials Genome Engineering in China显示文摘In the new round of global scientific and technological revolution and industrial transformation,one of the biggest bottlenecks we are facing is the lack of adequate materials technology.It is urgently hoped that there can be a major revolution in the materials research and development(R&D)field,rather than gradual and slow development[1].Under this background,materials genome engineering(MGE)has been developing rapidly,and its key technologies and engineering applications have become the frontiers of materials research[2]. | Jianxin Xie Yanjing Su Dawei Zhang Qiang Feng | 2022 | Engineering2022,8,3: | 3 |
| 4 | nfluence of swim-up time on the ratio of X- and Y-bearing spermatozoa显示文摘 | YanJ Feng HL Chen ZJ | 2006 | Eur J Obstet Gynecol Reprod Biol2006,129,2: | 1 |
| 5 | The discovery of archaea origin phosphomannomutase in algae based on the algal transcriptome显示文摘Phosphomannomutase(PMM;EC 5.4.2.8) is an enzyme that catalyzes the interconversion reaction between mannose-6-phosphate and mannose-1-phosphate.However,its systematic molecular and functional investigations in algae have not hitherto been reported.In this work,with the accomplishment of the 1 000 Plant Project(OneKP) in which more than 218 species of Chromista,including 19 marine phaeophytes,22 marine rhodophytes,171 chlorophytes,5 cryptophytes,4 haptophytes,and 5 glaucophytes were sequenced,we used a gene analysis method to analyze the PMM gene sequences in algae and confirm the existence of the PMM gene in the transcriptomic sequencing data of Rhodophyta and Ochrophyta.Our results showed that only one type of PMM with four conserved motifs exists in Chromista which is similar to human PMM.Moreover,the phylogenetic tree revealed that algae PMM possibly originated from archaea. | FENG Yanjing CHI Shan LIU Cui CHEN Shengping YU Jun WANG Xumin LIU Tao | 2014 | Acta Oceanologica Sinica2014,33,2: | 1 |
| 6 | Molecular level understanding of CO_(2) capture in ionic liquid/polyimide composite membrane显示文摘Ionic liquid(IL)/polyimide(PI)composite membranes demonstrate promise for use in CO_(2)separation applications.However,few studies have focused on the microscopic mechanism of CO_(2)in these composite systems,which is important information for designing new membranes.In this work,a series of systems of CO_(2)in 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide composited with 4,4-(hexafluoroisopropylidene)diphthalic anhydride(6FDA)-based PI,6FDA-2,3,5,6-tetramethyl-1,4-phenylene-diamine,at different IL concentrations were investigated by all-atom molecular dynamics simulation.The formation of IL regions in PI was found,and the IL regions gradually became continuous channels with increasing IL concentrations.The analysis of the radial distribution functions and hydrogen bond numbers demonstrated that PI had a stronger interaction with cations than anions.However,the hydrogen bonds among PI chains were destroyed by the addition of IL,which was favorable for transporting CO_(2).Furthermore,the self-diffusion coefficient and free energy barrier suggested that the diffusion coefficient of CO_(2)decreased with increasing IL concentrations up to 35 wt-%due to the decrease of the fractional free volume of the composite membrane.However,the CO_(2)selfdiffusion coefficients increased when the IL contents were higher than 35 wt-%,which was attributed to the formation of continuous IL domain that benefitted the transportation of CO_(2). | Linlin You Yandong Guo Yanjing He Feng Huo Shaojuan Zeng Chunshan Li Xiangping Zhang Xiaochun Zhang | 2022 | Frontiers of Chemical Science and Engineering2022,16,2: | 1 |
| 7 | A randomized controlled trial of ra- diofrequency ablation and surgical resection in the treatment of small hepatocellular carcinoma 显示文摘 | Feng K YanJ Li XW | 2012 | J Hepatol2012,57,4: | 1 |
| 8 | A Tag-based way of organizing and exploring literature resources in Web 2.0 environment显示文摘With the rapid development of Web2.0 technology,more and more social annotation systems are emerging,such as Del.icio.us,Flickr,YouTube,and CiteULike.These systems help users to manage and share their digital resources,and have attracted a lot of users to annotate the resources with tags and bookmarks,which result in a large scale of tag data.Due to the exponential increase of social annotations,all the users are facing the same problem:How can we explore the desired resources efficiently in such a large tag dataset?Since the traditional methods such as tag cloud view and annotation match work well only in small annotation dataset,this paper studies the relationships of tag-tag,tag-resource and resource-resource through the co-occurrences and proposes a new efficient way for users to organize and explore the literature resources.Our research mainly focuses on two aspects:1)The hidden semantic relationships of popular tags and their relevant literature resources;2)the computing of literature resources similarity given a specific literature.A prototype system named PKUSpace is implemented and shows promising results. | ZHANG Ming FENG Tianxiao HUANG Yanjing | 2008 | Chinese Journal of Library and Information Science2008,,1: | 0 |