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| 1 | 利用抗高血压药相关的遗传变异发现其潜在的功效和副作用显示文摘通过研究药物靶蛋白基因的自然变异可以了解药物的功效。本研究旨在利用这种方法探索抗高血压药的潜在副作用和再利用潜力。研究者首先确定了血管紧张素转换酶抑制剂(angiotensin converting enzyme inhibitor,ACEI)、β受体阻滞剂和钙拮抗剂的合适代表基因。 | 刘青(译) 叶鹏(校) Gill D Georgakis MK Koskeridis F Jiang L Feng Q Wei WQ Theodoratou E Elliott P Denny JC Malik R Evangelou E Dehghan A Dichgans M Tzoulaki I | 2019 | 中华高血压杂志2019，0，9： | 3 |
| 2 | 全颗粒饲料对奶牛生产性能的影响显示文摘饲料中的中性洗涤纤维(NDF)含量和饲料颗粒直径是影响瘤胃功能的重要因素。试验评估了以颗粒饲料为主的奶牛瘤胃健康情况、NDF消化率和生产性能。选取8头荷斯坦母牛(336±30 d,体重346±35 kg),随机分配到交叉重复试验组中,奶牛安置于牛栏,自由采食。试验期为3周,前两周是适应期,最后一周为数据收集期。各组饲粮原料相同,但物理形式不同,分为全混合日粮(TMR)和颗粒料(直径=8 mm)。两组间物理有效NDF(pe NDF)不同,TMR组为39.8%,颗粒料组为11.8%。在试验过程中,干物质采食量(DMI)、饮水量、瘤胃反刍时间、瘤胃温度和pH情况均记录。3周后收集粪样,确定潜在的可消化NDF总消化率(pdNDF)。每阶段结束后计算平均日增重和饲料转化率。颗粒料组的DMI、DMI/体重和饮水量更高。而两组间平均日增重和饲料转化率无显著差异。颗粒料组的瘤胃反刍时间为241 min·d-1低于TMR组的507 min·d-1。饲料的不同物理外形对瘤胃温度、瘤胃pH无显著影响。TMR组的pdNDF总消化率为90.25%高于颗粒料组的86.82%。试验结果表明,动物易接受完整的颗粒饲料,DMI较高,且反刍时间减少,但瘤胃pH无显著变化。TMR组的pdNDF消化率显著增加。尽管两组奶牛在DMI和纤维消化方面表现不同,但总体表现相似,两组饲料的保存时间与其物理形式有关。在短期内,提供能满足NDF需求的完全颗粒饲料可改善瘤胃健康状况和动物生产性能,而较长时间的数据则需要进一步试验。 | Wang J Yang M Cao M Lin Y Che L Q Duraipandiyan V Al-Dhabi N A Fang Z F Xu S Y Feng B Liu G Wu D Bonfante E Palmonari A Mammi L Canestrari G Fustini M Formigoni A | 2016 | 饲料博览2016，0，12： | 2 |
| 3 | Terahertz Semiconductor Quantum Well Devices显示文摘For eventually providing terahertz science with compact and convenient devices,terahertz (1~10THz) quantum-well photodetectors and quantum-cascade lasers are investigated.The design and projected detector performance are presented together with experimental results for several test devices,all working at photon energies below and around optical phonons.Background limited infrared performance (BLIP) operations are observed for all samples (three in total),designed for different wavelengths.BLIP temperatures of 17,13,and 12K are achieved for peak detection frequencies of 9.7THz(31μm),5.4THz(56μm),and 3.2THz(93μm),respectively.A set of THz quantum-cascade lasers with identical device parameters except for doping concentration is studied.The δ-doping density for each period varies from 3.2×1010 to 4.8×1010cm-2.We observe that the lasing threshold current density increases monotonically with doping concentration.Moreover,the measurements for devices with different cavity lengths provide evidence that the free carrier absorption causes the waveguide loss also to increase monotonically.Interestingly the observed maximum lasing temperature is best at a doping density of 3.6×1010cm-2. | Liu H C Luo H Ban D Waichter M Song C Y Wasilewski Z R Buchanan M Aers G C SpringThorpe A J Cao J C Feng S L Williams B S Hu Q | 2006 | Journal of Semiconductors2006，27，4： | 2 |
| 4 | Converting ceria polyhedral nanoparticles into single-crystal nanospheres 显示文摘 | Feng X D Sayle D C Wang Z L Paras M S Santora B Sutorik A C Sayle T X T Yang Y Ding Y Wang X D Her Y S | 2006 | Science2006，312，5779： | 1 |
| 5 | Studies on cleavage of DNA by N-phosphoryl branched peptides显示文摘 | Feng Y P Cao S L Xiao A S | 2006 | Peptides2006，27，6： | 1 |
| 6 | Petal effect, a superhydrophobic state with high adhesive force 显示文摘 | Feng L Zhang Y A Xi J M | 2008 | Langmuir2008，24，8： | 1 |
| 7 | Sequential Evaporation of Bi-Te Thin Films with Controllable Composition and Their Thermoelectric Transport Properties显示文摘 | ZHOU A J FENG L D CUI H G | 2013 | Journal of Electronic Materials2013，42，7： | 1 |
| 8 | Evidence for osteocyte regulation of bone homeostasis through RANKL expression显示文摘 | Nakashima T Hayashi M Fukunaga T Kurata K Oh-Hora M Feng J Q B onewald L F K odama T W utz A W agner E F Penninger JM Takayanagi H | | 0，，： | 1 |
| 9 | The chorion layer of fetal membranes is prematurely destroyed in women with preterm premature rupture of the membranes显示文摘 | Canzoneri B J Feng L Grotegut C A | 2013 | Reprod Sci2013，20，10： | 1 |
| 10 | Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent path way显示文摘 | Hanif R Pattas A Feng Y Koutsos MI Qiao L Staiano Coico L | 1996 | Biochem Pharmacol1996，52，： | 1 |
| 11 | The dynamic behavior of a gas bubble near a wall 显示文摘 | Zhang A M Yao X L Feng L H | 2009 | Ocean Engineering2009，36，： | 1 |
| 12 | A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes显示文摘 | GIAMARCHI A FENG S RODAT-DESPOIX L | 2010 | The EMBO Jour- nal2010，29，7： | 1 |
| 13 | Microstructure and low-cycle fatigue of a friction-stir-welded 6061 aluminum alloy显示文摘 | FENG A H CHEN D L MA Z Y | 2010 | Metallurgical and Materials Transactions A: Physical Metallurgy and Materials Science2010，41，10： | 1 |
| 14 | Stochastic construction timecost tradeoff analysis 显示文摘 | Feng C W Liu L Burns S A | 2000 | Journal of Computing in Civil Engineering2000，14，2： | 1 |
| 15 | Protective intesti- nal anti-rotavirus B cell immunity is dependent on a4137 integrin expression but does not require IgA antibody production显示文摘 | Kuklin N A Rott L Feng N | 2001 | J Immunol2001，166，3： | 1 |
| 16 | Structural, Electronic, and Optical Properties of Phosphole-Containing p-Conjugated Oligomers for Light-Emitting Diodes显示文摘 | Liu Y L Feng J K Ren A M | 2007 | J Comput Chem2007，28，： | 1 |
| 17 | An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability显示文摘 | WHITLOW M BELL B A FENG S L | 1993 | Protein Eng1993，6，8： | 1 |
| 18 | A group of Esche- richia coli and Salmonella enterica () antigens sharing a com- mon backbone structure显示文摘 | Wang W Perepelov A V Feng L | 2007 | Microbiology2007，153，7： | 1 |
| 19 | Determining the DNA bending angle induced by non-specific high mobility group-1 (HMG-1) proteins:a novel method 显示文摘 | TANG L LI J KATZ D S FENG J A | 2000 | Biochemistry2000，39，11： | 1 |
| 20 | Self-rated health of popula-tion in Southern China: association with socio -demo-graphic characteristics me asured with multiple -itemself-rated health measurement scale显示文摘 | Xu J Zhang J Feng L ef a/ | 2013 | BMC Public Health2013，，10： | 1 |
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