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    题名 作者 年代 出处 被引量
1Expression of inducible nitric oxide synthase in human gastric cancer显示文摘Jun Y Fei G Ebert MP Malfertheiner P 1999World Journal of Gastroenterology1999,5,5:5
2笋芽顶端分生组织在竹秆横切面形态形成中的作用与机制研究显示文摘竹秆的横切面主要由表皮、皮层、维管组织、基本组织及髓腔(早期为髓组织)组成。这些组织均由笋芽茎顶端分生组织分化发育而来,且其在生长发育过程中促使了竹秆横切面形态(本文特指:竹秆横切面外轮廓形状、围度及壁-腔结构)的形成。然而,人们对于这一生长发育过程的生物学机制知之甚少。本研究利用解剖学、数学模拟等方法,对 20 种具不同秆径竹种的笋芽顶端分生组织进行了分析。研究结果发现,笋芽顶端分生组织指状形态的维持是竹子产生圆柱形竹秆的基础;在顶端分生组织细胞数目增加的同时,线性增加原体细胞数目应是竹子在演化过程中产生大径竹秆且保持规则壁-腔结构的方式。进一步通过研究一个竹壁增厚且壁-腔架构紊乱的稳定变异体———实肚竹( Phyllostachys nidularia f. farcta)发现,其笋芽顶端分生组织细胞数目减少且原体/原套细胞数比值降低使其产生了高比例的壁组分组织(指基本分生组织与肋状分生组织)与低比例的髓组织。上述 2 种组织的比例失衡,使得实肚竹笋芽在后续发育中壁组分组织随机挤入到了髓组织中,最终形成了实肚竹异常的竹秆横切面形态(竹壁多样化增厚且壁-腔结构紊乱)。此外,相对较小的顶端分生组织,使得实肚竹笋芽产生了较少的内源激素,如其生长素含量仅约为其原种篌竹的 67. 5%,各细胞分裂素含量也显著低于篌竹笋芽。转录组分析进一步发现,在实肚竹笋芽中与激素及代谢相关的功能基因呈显著下调表达。这些生理与分子变化最终导致了实肚竹竹秆矮化、秆径减小且生物量降低。本论文的研究结果为研究竹秆横切面发育提供了一个重要的视角,同时也为实肚竹厚壁茎秆的形成提出了一个合理的机制。Wang Y Sun X Ding Y Fei Z Jiao C Fan M Yao B Xin P Chu J Wei Q 王雨珺 魏强 2019世界竹藤通讯2019,17,3:5
3Interleukin-10 gene polymorphisms and hepatocellular carcinoma susceptibility:A meta-analysis显示文摘AIM: To assess the association between Interleu-kin-10 (IL-10) gene IL-10-1082 (G/A), IL-10-592(C/A), IL-10-819 (T/C) polymorphisms and hepatocellular carcinoma (HCC) susceptibility.METHODS: Two investigators independently searched the Medline, Embase, China National Knowledge Infrastructure, and Chinese Biomedicine Database. Summary odds ratios (ORs) and 95% conf idence intervals (95% CIs) for IL-10 polymorphisms and HCC were cal-culated in a fixed-effects model (the Mantel-Haenszel method) and a random-effects model (the DerSimonian and Laird method) when appropriate. RESULTS: This meta analysis included seven eligiblestudies, which included 1012 HCC cases and 2308 controls. Overall, IL-10-1082 G/A polymorphism was not associated with the risk of HCC (AA vs AG + GG, OR = 1.11, 95% CI = 0.90-1.37). When stratifying for ethnicity, the results were similar (Asian, OR = 1.12, 95% CI = 0.87-1.44; non-Asian, OR = 1.10, 95% CI = 0.75-1.60). In the overall analysis, the IL-10 polymorphism at position -592 (C/A) was identified as a genetic risk factor for HCC among Asians; patients carrying the IL-10-592*C allele had an increased risk of HCC (OR = 1.29, 95% CI = 1.12-1.49). No association was observed between the IL-10-819 T/C polymorphism and HCC susceptibility (TT vs TC + CC, OR = 1.02, 95% CI = 0.79-1.32).CONCLUSION: This meta-analysis suggests that IL-10-592 A/C polymorphism may be associated with HCC among Asians. IL-10-1082 G/A and IL-10-819 T/C polymorphisms were not detected to be related to the risk for HCC.Yong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin YangYong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin Yang, Department of Liver and Vascular Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Prov- ince, China Author contributions: Wei YG and Liu F designed the study, collected and analyzed the data and wrote the manuscript Li B collected and analyzed the data and wrote the manuscript Chen X and Ma Y collected and analyzed the data Yan LN analyzed the data and contributed to the discussion Wen TF and Xu MQ revised the manuscript Wang WT and Yang JY contributed to the discussion Wei YG and Liu F contributed equally to this work. 2011World Journal of Gastroenterology2011,17,34:3
4非典型病原体感染在社区获得性肺炎中的地位显示文摘社区获得性肺炎(CAP)是对危害人类健康的常见疾病之一。部分住院CAP患者会发展成重症社区获得性肺炎(SCAP)并需入住ICU治疗。由于并发症的频繁出现和住院治疗时间较长,此类患者的病死率很高。尽管CAP流行病学在各个国家及随时间变化而有所不同,但非典型病原体在全世界CAP中起重要作用。在中国,非典型病原体如肺炎支原体、肺炎衣原体和嗜肺军团菌是CAP重要病原体,其中肺炎支原体是最常见的病原体。Yu Y Fei A 2017中国实用内科杂志2017,37,2:2
5Quality control measures for lowering the seroconversion rate of hemodialysis patients with hepatitis B or C virus显示文摘BACKGROUND: Hemodialysis (HD) patients are at high risk of infection by hepatitis B virus (HBV) or hepatitis C virus (HCV). The present study was designed to determine the impact of quality control measures on the prevention of transmission of blood-borne viruses. METHODS: A total of 6182 adult maintenance HD patients from all HD units in Zhejiang Province were recruited on January 1, 2007. The baseline demographic and clinical characteristics were recorded and all patients were followed up until death or survival at 4 years later. The Quality Control Standards of Hemodialysis were gradually implemented in HD units. The HBV or HCV seroconversion rates of the recruited patients were calculated and compared every year during the observation period. RESULTS: The prevalence of HBV was 8.3% at the beginning of the study, and 6.6% for HCV. With the implementation of the HD quality control measures, the HBV seroconversion rate tended to decrease year by year (χ 2 =6.620, P=0.085), and the HCV seroconversion rate decreased significantly (χ 2 =10.41, P=0.015). Compared with the data in 2007, the HBV seroconversion rate (χ 2 =4.204, P=0.040, relative risk ratio 0.393, 95% CI 0.156-0.991) and the HCV seroconversion rate (χ 2 =7.373, P=0.007, relative risk ratio 0.386, 95% CI 0.189-0.787) decreased significantly in 2010. CONCLUSION: Quality control measures for HD decreased the seroconversion rates of HBV or HCV in HD patients, showing that updated quality control measures reduce the risk for transmission of blood-borne viruses in the HD population.Jing Yuan,Yi Yang, Fei Han, Ping Zhang, Xiao-Ying Du, Hua Jiang and Jiang-Hua Chen The Kidney Disease Center, First Affiliated Hospital, Zhejiang University School of Medicine (Yuan J, Yang Y, Han F, Zhang P, Du XY, Jiang H and Chen JH) and Hemodialysis Quality Control Center of Zhejiang Province (Yuan J, Zhang P, Du XY and Chen JH), Hangzhou 310003, China 2012Hepatobiliary & Pancreatic Diseases International2012,11,3:2
6Clinical features of retinal diseases masquerading as retrobulbar optic neuritis显示文摘JIANG Li-bin SHEN Ce-ying CHEN Fei YAN Wei-yu Timothy Y. Y WANG Ning-li 2013Chinese Medical Journal2013,,17:2
7Development of a rat C6brain tumor model 显示文摘 Wu JW Gao DK Fei Z Qu Y 2002Chin Med J2002,115,3:1
8High-Pressure Iron-Sulfur Compound, Fe3S2, and Melting Relations in the Fe-FeS System 显示文摘FEI Y BERTKA C M FINGER L W 1997Science1997,275,3:1
9A critical evaluation of pressure scales at high temperatures by in situ X-ray diffraction measurements显示文摘FEI Y W LI H HIROSE K 2004Phys Earth Planet Int2004,,:1
10Micromorphology and phase behavior of cationic polyurethane segmented copo- lymer modified with hydroxysilane显示文摘WANG H H SHEN Y D FEI G Q 2008Journal of Colloid and Interface Science2008,324,12:1
11Structure,function and immunolocalization of a proton coupled amino acid trans porter (hPAT1) in the human intestinal cell line Caco-2显示文摘Chen Z Fei Y J Anderson C M H 2003The Journal of Physiology2003,546,2:1
12Identification of proteins indu-cing short-lived antibody responses from excreted/secretory prod-ucts of Schistosoma japonicum adult worms by immunoproteomicanalysis显示文摘Jie W’ Fei Z Chuanxin Y 2013J Proteomics2013,,87:1
13Claudin-6 and Claudin-9 function as additional coreceptors for hepatitis C virus 显示文摘Aihua Z Fei Y Yanqin L 2007J Virol2007,8,12:1
14Synthesis and crystal structure of a luminescent infinite 2D brick-wall network with two- and three-coordinate silver (I) atoms and ligand-unsupported silver - silver interactions显示文摘Fei B L Sun W Y Okamura T 2001New J Chem2001,25,:1
15Cloning of the sodium-dependent,broad-scope,neutral amino acid transporter Bo from a human placental choriocarcinoma cell line显示文摘Kekuda R Prasad P D Fei Y J 1996Biol Chem1996,271,18:1
16How much potassium is in the Earth's core ? New insights from partitioning experiments 显示文摘Corgne A Keshav S Fei Y 2007Earth and Planetary Science Letter2007,256,:1
17Beneficial properties for insulin absorption using superporous hydrogel containing interpenetrating polymer network as oral delivery vehicles 显示文摘Yin L C Ding J Y Fei L K 2008International Journal of Pharmaceutics2008,350,12:1
18Effect of phenolic resin content on performance of carbon fiber reinforced paper-based friction ma- terial 显示文摘Fei J Li H J Fu Y W 2010Wear2010,269,78:1
19Growth of Gracilaria lemaneiformis under different cultivation conditions and its effects on nutrient removal in Chinese coastal waters显示文摘YABG Y FEI X SONG J 2006Aquaculture2006,254,14:1
20Expression cloning of a mammalian protroncoupled oligo- peptide transporter 显示文摘Fei yj Y Kanaai S Nussberger 1994Nature1994,368,:1
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