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| 1 | The clinical effectiveness of reflectance optical spectroscopy for the in vivo diagnosis of oral lesions显示文摘Optical spectroscopy devices are being developed and tested for the screening and diagnosis of oral precancer and cancer lesions. This study reports a device that uses white light for detection of suspicious lesions and green–amber light at 545 nm that detect tissue vascularity on patients with several suspicious oral lesions. The clinical grading of vascularity was compared to the histological grading of the biopsied lesions using specific biomarkers. Such a device, in the hands of dentists and other health professionals, could greatly increase the number of oral cancerous lesions detected in early phase. The purpose of this study is to correlate the clinical grading of tissue vascularity in several oral suspicious lesions using the IdentafiH system with the histological grading of the biopsied lesions using specific vascular markers. Twenty-one patients with various oral lesions were enrolled in the study. The lesions were visualized using IdentafiH device with white light illumination, followed by visualization of tissue autofluorescence and tissue reflectance. Tissue biopsied was obtained from the all lesions and both histopathological and immunohistochemical studies using a vascular endothelial biomarker(CD34) were performed on these tissue samples. The clinical vascular grading using the green–amber light at 545 nm and the expression pattern and intensity of staining for CD34 in the different biopsies varied depending on lesions, grading ranged from 1 to3. The increase in vascularity was observed in abnormal tissues when compared to normal mucosa, but this increase was not limited to carcinoma only as hyperkeratosis and other oral diseases, such as lichen planus, also showed increase in vascularity. Optical spectroscopy is a promising technology for the detection of oral mucosal abnormalities; however, further investigations with a larger population group is required to evaluate the usefulness of these devices in differentiating benign lesions from potentially malignant lesions. | Diana V Messadi Fariba S Younai Hong-Hu Liu Gao Guo Cun-Yu Wang | 2014 | International Journal of Oral Science2014，6，3： | 2 |
| 2 | Thirty years of the human immunodeficiency virus epidemic and beyond显示文摘After more than 30 years of battling a global epidemic, the prospect of eliminating human immunodeficiency virus(HIV) as the most challenging infectious disease of the modern era is within our reach. Major scientific discoveries about the virus responsible for this immunodeficiency disease state, including its pathogenesis, transmission patterns and clinical course, have led to the development of potent antiretroviral drugs that offer great hopes in HIV treatment and prevention. Although these agents and many others still in development and testing are capable of effectively suppressing viral replication and survival, the medical management of HIV infection at the individual and the population levels remains challenging. Timely initiation of antiretroviral drugs, adherence to the appropriate therapeutic regimens, effective use of these agents in the pre and post-exposure prophylaxis contexts, treatment of comorbid conditions and addressing social and psychological factors involved in the care of individuals continue to be important considerations. | Fariba S Younai | 2013 | International Journal of Oral Science2013，5，4： | 2 |
| 3 | Comparison of chitosan-gelatin composite and bilayer coating and film effect on the quality of refrigerated rainbow trout显示文摘 | Fariba N Bahareh S Se y ed M O | 2013 | Food chemisty2013，141，3： | 1 |
| 4 | Effect of timing of umbilical cord clamp on newborns' iron status and its relation to de- livery type显示文摘 | Fariba S Mitra R Mojgan H | 2010 | Archives of Iranian Medicine2010，13，5： | 1 |
| 5 | Novel Method for the Synthesis of 1,2,4-Oxadiazoles Using Alumina Supported Ammonium Fluoride under Solvent-free Condition显示文摘 | BABAK K FARIBA S | 2005 | Journal of Heterocyclic Chemistry2005，42，4： | 1 |
| 6 | Bacterial inactivation by using near and supercritical carbon dioxide Nati Acad显示文摘 | Angela K Dillow Fariba Dehghani Jeffrey S Hrkach | 1999 | Sci USA1999，96，10： | 1 |
| 7 | Pemphigus foliaceus 显示文摘 | Fariba G Ayatollahi A Hejazi S | 2012 | In- dian Pediatrics2012，49，3： | 1 |
| 8 | Endostatin inhibits angiogenesis by stabilization of newly formed endothelial tubes显示文摘 | Süleyman Ergün Nerbil Kilic Jan-Henner Wurmbach Alireza Ebrahimnejad Malkanthi Fernando Sema Sevinc Ergin Kilic Fariba Chalajour Walter Fiedler Heidrun Lauke Katrin Lamszus Peter Hammerer Joachim Weil Hermann Herbst Judah Folkman | 2001 | Angiogenesis2001，，3： | 1 |
| 9 | Effects of recombinant hu man IGF-I/IGF-binding protein 3 complex on glucose and glyc erol metabolism in type 1 diabetes 显示文摘 | Tero S Fariba S M Rachel M | 2006 | Diabetes2006，55，： | 1 |
| 10 | Endostatin inhibits angiogenesis by stabilization of newly formed endothelial tubes显示文摘 | Süleyman Ergün Nerbil Kilic Jan-Henner Wurmbach Alireza Ebrahimnejad Malkanthi Fernando Sema Sevinc Ergin Kilic Fariba Chalajour Walter Fiedler Heidrun Lauke Katrin Lamszus Peter Hammerer Joachim Weil Hermann Herbst Judah Folkman | 2001 | Angiogenesis2001，，3： | 1 |
| 11 | An Information- Motivation-Behavioral Skills(IMB) Model-Based Intervention for CABG Patients显示文摘 | Fariba Z Mohammad AB Gholamreza S | 2012 | Int J Behav2012，19，4： | 1 |
| 12 | Modes of Glucuronyl C5 Epimerization, Iduronic Acid 2-O-Sulfation, and Glueosamine 6-O-Sulfation 显示文摘 | Fariba S Lindahl U Markku S | 2000 | Biochemistry2000，39，10： | 1 |
| 13 | Effects of recombinant human IGF-Ⅰ/IGF-binding protein-3 complex on glucose and glycerol metabolism in type 1 diabetes显示文摘 | Tero S Fariba S M Rachel M l | 2006 | Diabetes2006，55，： | 1 |
| 14 | Major flavonoids with antioxidant activity from teucrium polium L 显示文摘 | Fariba S Gholamreza D N Mansour M | 2009 | Food Chem2009，112，4： | 1 |
| 15 | Modes of Glueuronyl C5 Epimerization, Iduronic Acid 2-O-Sulfation, and Glueosamine 6-O-Sulfation 显示文摘 | Fariba S Lindahl U Markku S | 2000 | Biochemistry2000，39，10： | 1 |
| 16 | An Intelligent Multi Agent Design in Healthcare Management System 显示文摘 | Dharmendra S Fariba S | 2008 | Lecture Notes in Computer Science (S0302-9743)2008，4953，1： | 1 |
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