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| 1 | MicroRNAs as novel regulators of stem cell fate显示文摘Mounting evidence in stem cell biology has shown that microRNAs(miRNAs) play a crucial role in cell fate specification, including stem cell self-renewal, lineagespecific differentiation, and somatic cell reprogramming.These functions are tightly regulated by specific gene expression patterns that involve miRNAs and transcription factors. To maintain stem cell pluripotency, specific miRNAs suppress transcription factors that promote differentiation, whereas to initiate differentiation, lineagespecific miRNAs are upregulated via the inhibition of transcription factors that promote self-renewal. Small molecules can be used in a similar manner as natural miRNAs, and a number of natural and synthetic small molecules have been isolated and developed to regulate stem cell fate. Using miRNAs as novel regulators of stem cell fate will provide insight into stem cell biology and aid in understanding the molecular mechanisms and crosstalk between miRNAs and stem cells.Ultimately, advances in the regulation of stem cell fate will contribute to the development of effective medical therapies for tissue repair and regeneration. This review summarizes the current insights into stem cell fate determination by miRNAs with a focus on stem cell self-renewal, differentiation, and reprogramming. Small molecules that control stem cell fate are also highlighted. | Eunmi Choi Ki-Chul Hwang | 2013 | World Journal of Stem Cells2013，5，4： | 8 |
| 2 | Heterostructures in two-dimensional colloidal metal chalcogenides:Synthetic fundamentals and applications显示文摘As a new class of two-dimensional materials, two-dimensional (2D) heterostructures constructed from metal chalcogenides (MCs) have been gaining tremendous attention due to their unprecedented physical and chemical phenomena, mainly originated from their distinct structural features such as composition, architecture type, spatial arrangement of each component, crystal structure, exposed facet and interface, dimensionality in their heterostructures. Towards the realization of practical applications, synthetic approaches need a rational design with a variety of architecture types including laterally-combined, vertically-aligned, and conformally-coated 2D MC heterostructures. Among various synthetic routes, solution-based synthesis is thought of as an alternative to fabrication through high-cost setups since it can control those structural features in a cheap fashion. This review presents recent progress on solution-based synthesis to produce various 2D MC heterostructures with a focus on the synthetic fundamentals in terms of thermodynamic and kinetic aspects related to the growth mechanism. Four different synthetic approaches are reviewed: seeded growth, cation exchange reaction, colloidal atomic layer deposition, direct synthesis including one-step process and modified electrochemical method. We also provide some representative applications of 2D MC heterostructures and their hybrid composites in various fields including optoelectronics, thermoelectrics, catalysis, and battery. Finally, we offer an insight into challenges and future directions in a synthetic improvement of 2D MC heterostructures. | Yuho Min Eunmi Im Geon-Tae Hwang Jong-Woo Kim Cheol-Woo Ahn Jong-Jin Choi Byung-Dong Hahn Joon-Hwan Choi Woon-Ha Yoon Dong-Soo Park Dong Choon Hyun Geon Dae Moon | 2019 | Nano Research2019，12，8： | 6 |
| 3 | Perceived risk as a barrier to appropriate diagnosis of irritable bowel syndrome显示文摘AIM:To evaluate perceived risk,diagnostic testing,and acceptance of a diagnosis of irritable bowel syndrome(IBS)among the Korean laypersons.METHODS:We designed a conceptual framework to evaluate the health-seeking behavior of subjects based on a knowledge,attitude,and practice model.We developed a vignette-based questionnaire about IBS based on a literature review and focused group interviews.The vignette described a 40-year-old woman who meets the RomeⅢcriteria for IBS without red-flag signs.It was followed by questions about demographic characteristics,health behaviors,IBS symptoms,risk perception,perceived need for diagnostic tests,and acceptance of a positive diagnosis of IBS.Weplanned a nationwide survey targeting laypersons without IBS and between the ages of 20 and 69 years.Survey participants were selected by quota sampling stratified by gender,age,and nationwide location.A multivariate logistic model was constructed based on literature reviews,univariate analysis,and a stepwise selection method to investigate correlations between the perceived risk,need for diagnostic tests,and acceptance of a positive diagnosis.RESULTS:Of 2354 eligible households,1000 subjects completed the survey and 983 subjects were analyzed,excluding those who met symptom criteria for IBS.After reading the IBS vignette,the majority of subjects(86.8%)responded that the patient was at increased risk of severe disease.The most frequent concern was colon cancer(59.8%),followed by surgical condition(51.5%).Most subjects responded the patient needs diagnostic tests(97.2%).Colonoscopy was the most commonly required test(79.5%).Less than half of the respondents requested a stool examination(45.0%),blood test(40.7%),abdominal ultrasound(36.0%),or computed tomography(20.2%).The subjects who felt increased risk were more likely to see a need for colonoscopy[adjusted odds ratio(a OR)=2.10,95%CI:1.38-3.18].When asked about the positive diagnosis,the most frequent response was that'the patient would not be reassured'(65.7%).The increased risk perception group was less likely to be reassured by a positive diagnosis of IBS,compared to the other respondents(a OR=0.52,95%CI:0.34-0.78).CONCLUSION:For IBS diagnosis,increased risk perception is a possible barrier to the appropriate use of diagnostic tests and to the patient’s acceptance of a positive diagnosis. | Eunmi Ahn Ki Young Son Dong Wook Shin Min Kyu Han Hyejin Lee Ah Reum An Eun Ho Kim Be Long Cho | 2014 | World Journal of Gastroenterology2014，20，48： | 2 |
| 4 | Performance test and analysis for an adaptive load balancing mechanism on distributed server cluster systems显示文摘 | Eunmi Choi | 2004 | Future Generation Computing Systems2004，20，： | 1 |
| 5 | CpG Island Methylator Phenotype is Associated With Response to Adjuvant Irinotecan-Based Therapy for Stage 3 Colon Cancer显示文摘 | Stacey Shiovitz Monica M. Bertagnolli Lindsay A. Renfro Eunmi Nam Nathan R. Foster Slavomir Dzieciatkowski Yanxin Luo Victoria Valinluck Lao Raymond J. Monnat Mary J. Emond Nancy Maizels Donna Niedzwiecki Richard M. Goldberg Leonard B. Saltz Alan Venook R | 2014 | Gastroenterology2014，，： | 1 |
| 6 | Analysis of carbamazepine and its active metabolite, carbamazepine-10, 11- epoxide, in human plasma using high-performance liquid chromatography显示文摘 | Eun kyung Oh Eunmi Ban Jong Soo Woo | 2006 | Anal Bioanal Chem2006，386，6： | 1 |
| 7 | Determination of ethyl carbamate in some fermented Korean foods and beverages显示文摘 | Young-Kyung Lee Kim Eunmi Koh Hyun-Jung Chung Hoonjeong Kwon | 2000 | Food Additives & Contaminants: Part A2000，，： | 1 |
| 8 | Sensitive column-switching high-performance liquid chromatography method for determination of propivefine in human plasma 显示文摘 | EUNMI BAN JEONG EUN MAENG JONG SOO WOO | 2006 | Journal of Chromatography B2006，831，： | 1 |
| 9 | Composite Effects of Extrinsic Motivation on Work Effort: Case of Korean Employees显示文摘 | Chang Eunmi | 2003 | Journal of World Business2003，38，1： | 1 |
| 10 | Nonalcoholic fatty liver disease predicts chronic kidney disease in nonhypertensive and nondiabetic Korean men显示文摘 | Yoosoo Chang Seungho Ryu Eunju Sung Hee-Yeon Woo Eunock Oh Kyungsoo Cha Eunmi Jung Won Sool Kim | 2008 | Metabolism2008，，4： | 1 |
| 11 | The effects of Angelica keiskei Koidz on the expression of antioxidant enzymes related to lipid profiles in rats fed a high fat diet显示文摘 | EUNMI KIM JINHO CHOI IKHYUN YEO | 2012 | Nutrition Research and Practice2012，6，1： | 1 |
| 12 | A randomized trial of anemia correction with two different hemoglobin targets in the first-line chemotherapy of advanced gastric cancer显示文摘 | Se Hoon Park Eunmi Nam Soo-Mee Bang Eun Kyung Cho Dong Bok Shin Jae Hoon Lee | 2008 | Cancer Chemotherapy and Pharmacology2008，，1： | 1 |
| 13 | Performance test and analysis for an adaptive load balancing mechanism on distributed server cluster systems显示文摘 | Eunmi Choi | 2003 | Future Generation Computer Systems2003，，2： | 1 |
| 14 | Performance test and analysis for an adaptive load balancing mechanism on distributed server cluster systems 显示文摘 | Eunmi Choi | 2004 | Future Generation Computer Systems2004，，20： | 1 |
| 15 | Does pay-for-performance enhance perceived distributive justice for collectivistic employees?显示文摘 | Eunmi Chang Juhee Hahn | 2006 | Personnel Review2006，，4： | 1 |
| 16 | Ferrocene end-capped dendrimer:synthesis and application to CO gas sensor显示文摘 | Chungkyun Kim Eunmi Park ea al | 2001 | Synthedis Metals2001，123，： | 1 |
| 17 | Employees' overall perception of HRM effectiveness显示文摘 | Eunmi Chang | 2005 | Human Relations2005，58，4： | 1 |
| 18 | Mitomycin C plus S-1 as second-line therapy in patients with advanced gastric cancer: a noncomparative phase II study显示文摘 | Se Hoon Park Young Saing Kim Junshik Hong Jinny Park Eunmi Nam Eun Kyung Cho Dong Bok Shin Jae Hoon Lee Woon Kee Lee Min Chung | 2008 | Anti-Cancer Drugs2008，，3： | 1 |
| 19 | Individual pay for performance and commitment HR practices in South Korea 显示文摘 | Eunmi Chang | 2006 | Journal of World Business2006，41，： | 1 |
| 20 | The role of microRNA-23b in the differentiation of MSC into chondrocyte by targeting protein kinase A signaling显示文摘 | Onju Ham Byeong-Wook Song Se-Yeon Lee Eunmi Choi Min-Ji Cha Chang Youn Lee Jun-Hee Park Il-Kwon Kim Woochul Chang Soyeon Lim Chang Hyun Lee Soonhag Kim Yangsoo Jang Ki-Chul Hwang | 2012 | Biomaterials2012，，18： | 1 |
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