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您的检索式：作者名="Esmail ABBASI"
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| 1 | 大荨麻提取物对高胆固醇血症大鼠血脂的影响(英文)显示文摘目的:探讨大荨麻提取物对高胆固醇血症大鼠血脂的影响。方法:雄性大鼠口服高胆固醇饮食(10mL/kg)4周,制备高胆固醇血症大鼠模型。造模同时灌服100、300mg/kg大荨麻提取物或10mg/kg洛伐他汀。观察大荨麻提取物对大鼠血脂、肝功能和肝脏病理的影响。结果:100、300mg/kg大荨麻提取物可以明显减少高胆固醇血症大鼠血总胆固醇和低密度脂蛋白胆固醇含量,并可以降低丙氨酸氨基转移酶(alanine aminotransferase,ALT)和天冬氨酸氨基转移酶(aspartate aminotransferase,AST)活性。苏木精和伊红染色显示,100mg/kg大荨麻提取物组肝脏组织未见明显脂肪变性,细胞形态与对照组相似;300mg/kg大荨麻提取物组肝脏组织可见到中等程度的脂肪变性。结论:大荨麻提取物可能通过降低血浆胆固醇含量和血浆ALT、AST活性治疗大鼠高胆固醇血症。 | Marjan NASSIRI-ASL Farzaneh ZAMANSOLTANI Esmail ABBASI Mohammad-Mehdi DANESHI Amir-Abdollah ZANGIVAND | 2009 | 中西医结合学报2009，7，5： | 7 |
| 2 | Effects of rutin on oxidative stress in mice with kainic acid-induced seizure显示文摘OBJECTIVE:Flavonoids are present in foods such as fruits and vegetables.Several studies have demonstrated a relationship between the consumption of flavonoid-rich foods and prevention of human disease,including neurodegenerative disorders.We assessed the effect of rutin(quercetin-3-O-rutinoside)on oxidative stress in kainic acid(KA)-induced seizure.METHODS:Thirty-six BALB/c mice were randomly divided into three groups.In the control group,saline(intra-peritoneal,i.p.)was administered for 7 d,and on the last day,KA(10 mg/kg,i.p.)was injected 30 min after administration of saline.In rutin groups,mice were pretreated with rutin(100 and 200 mg/kg,i.p.)for 7 d,and on the last day,KA(10 mg/kg,i.p.)was injected30 min after administration of rutin.Subsequently,behavioural changes were observed in mice.Lipid peroxidation and oxidative stress were measured respectively in the early and late phases after KA-induced seizures.RESULTS:Seizure scores in the rutin groups were significantly lower than those in the control group(P<0.01).Furthermore,rutin dose-dependently inhibited the number of wet-dog shakes(WDS)(P<0.05).Malondialdehyde level in the hippocampus of the rutin groups was significantly lower than that in the hippocampus of the control group on days 1 and 21 after KA administration.In the rutin groups,the thiol levels observed on day 1 after KA administration were higher than that in the control group(P<0.01).CONCLUSION:These results indicate that rutin has potential anticonvulsant and antioxidative activities against oxidative stress in KA-induced seizure in mice. | Marjan Nassiri-Asl Taghi Naserpour Farivar Esmail Abbasi Hamid Reza Sadeghnia Mehdi Sheikhi Mina Lotfizadeh Parisa Bazahang | 2013 | Journal of Integrative Medicine2013，11，5： | 1 |
| 3 | Solving linear optimization problems with max-star composition equation constraints显示文摘 | Esmaile Khorram Amin Ghodousian Ali Abbasi Molai | 2006 | Applied Mathematics and Computation2006，179，2： | 1 |
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