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2篇 您的检索式:作者名="Eric Padron"
    题名 作者 年代 出处 被引量
1Clinical management of myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes显示文摘The myelodysplastic/myeloproliferative neoplasms(MDS/MPNs) are a unique group of hematologic malignancies characterized by concomitant myelodysplastic and myeloproliferative features. According to the 2008 WHO classification, the category includes atypical chronic myeloid leukemia(a CML), chronic myelomonocytic leukemia(CMML), juvenile myelomonocytic leukemia(JMML), MDS/MPN-unclassifiable(MDS/MPN-U), and the provisional entity refractory anemia with ring sideroblasts and thrombocytosis(RARS-T). Although diagnosis currently remains based on clinicopathologic features, the incorporation of nextgeneration platforms has allowed for the recent molecular characterization of these diseases which has revealed unique and complex mutational profiles that support their distinct biology and is anticipated to soon play an integral role in diagnosis,prognostication, and treatment. Future goals of research should include the development of disease-modifying therapies, and further genetic understanding of the category will likely form the foundation of these efforts.Joseph A.Clara David A.Sallman Eric Padron 2016Cancer Biology & Medicine2016,13,3:4
2The molecular basis and clinical significance of genetic mutations identified in myelodysplastic syndromes显示文摘Ling Zhang Eric Padron Jeffrey Lancet 2014Leukemia Research2014,,:1
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