|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Lactobacilli,bifi dobacteria and E.coli nissle induce pro-and anti-inflammatory cytokines in peripheral blood mononuclear cells显示文摘AIM: To investigate whether the stimulation of peripher- al blood mononuclear cells (PBMNC) with the cell debris and cell extraction of different probiotic strains is similar or species specifi c. METHODS: Three strains of bifi dobacteria, 4 strains of lactobacilli, and E. coli nissle were sonicated and centri- fuged in order to divide them into cell extract and cell debris. PBMNC were separated by density gradient and incubated for 36 h with either the cell debris or the cell extract of single strains of probiotic bacteria in doses from 102 to 108 CFU/mL. Cell supernatants were taken and interleukin (IL)-10, IL-1β, and tumor necosis factor (TNF)-α were determined by ELISA. RESULTS: Depending on the species super-family, the strains had different stimulation patterns. Except for both L. casei strains, the cell extract of bifidobacteriaand lactobacilli had less stimulating capacity than cell debris, whereas the cell extract of E. coli nissle had simi- lar stimulating properties to that of the cell debris of the strain and significantly more stimulating capacity than that of bifi dobacteria and lactobacilli. The cell debris of bifi dobacteria stimulated more cytokine release than the cell debris of lactobacilli. The cell debris of lactobacilli did not have a stimulating capacity when lower concentra- tions were used. Neither cell extraction nor cell debris had an inhibitory effect on the production of the tested cytokines by stimulated PBMNC. CONCLUSION: The incubation of probiotic strains, which have been used in clinical trials for inflammatory diseases, with immunocompetent cells leads to different species specifi c reactions. High IL-10 response to cell de- bris of bifi dobacteria and E. coli nissle can be found. This corresponds to positive effects of bifi dobacteria and E. coli nissle in clinical trials for inflammatory bowel disease compared to negative outcomes obtained with lactoba- cilli. | Ulf Helwig Karen M Lammers Fernando Rizzello Patricia Brigidi Verena Rohleder Elisabetta Caramelli Paolo Giochetti Juergen Schrezenmeir Ulrich R Foelsch Stefan Schreiber Massimo Campieri | 2006 | World Journal of Gastroenterology2006，12，37： | 3 |
| 2 | Association of nonalcoholic fatty liver disease with insulin resistance显示文摘 | Giulio Marchesini Mara Brizi Antonio M Morselli-Labate Giampaolo Bianchi Elisabetta Bugianesi Arthur J McCullough Gabriele Forlani Nazario Melchionda | 1999 | The American Journal of Medicine1999，，5： | 2 |
| 3 | Copper-induced changes of non-protein thiols and antioxidant enzymes in the marine microalga Phaeodactylum tricornutum显示文摘 | Elisabetta M Gioacchino S 2004 | 2004 | Plant Sci2004，167，： | 1 |
| 4 | The environmental Kuznets curve: de-velopment path or policy result? 显示文摘 | Elisabetta M | 2001 | Environmental Modeling b- Software2001，16，2： | 1 |
| 5 | Fine particle concentrations in buses and taxis in Florence,Italy显示文摘 | Fondelli M C Elisabetta Chellini Tarja Yli-Tuomi | 2008 | Atmospheric Environment2008，42，35： | 1 |
| 6 | The electrchromic response of polyaniline and its copolymeric systems 显示文摘 | Manoj K R Elisabetta M Claudio N | 1997 | Thin Solid Films1997，303，： | 1 |
| 7 | Cerium(Ⅲ) chloride promote d chemoselective esterification of phenolic-alcohols 显示文摘 | Elisabetta T Gianfranco S Alberto M | 2005 | Tetrahedron Letters2005，46，： | 1 |
| 8 | Assessment of nutritional status in free living elderly individuals by bioelectrical impedance vector analysis 显示文摘 | Roberto B 6iovanni F Elisabetta M | 2009 | btrition2009，25，： | 1 |
| 9 | Solid lipid nanoparticles as delivery systems for bromocriptine 显示文摘 | ELISABETTA E MARTINA F MATTEO M | 2008 | Pharm Res2008，25，7： | 1 |
| 10 | Electrochemical Detection of the Toxic Organohalide 2,4-DB Using a Co-porphyrin Based Electrosynthesized Molecularly Imprinted Polymer显示文摘 | Elisabetta M Cosimino M | 2010 | Sens Actuators B2010，148，1： | 1 |
| 11 | The prevalence of celiac disease in Europe: Results of a centralized, international mass screening project显示文摘 | Kirsi Mustalahti Carlo Catassi Antti Reunanen Elisabetta Fabiani Margit Heier Stan McMillan Liam Murray Marie-Helene Metzger Maurizio Gasparin Enzo Bravi Markku M?ki | 2010 | Annals of Medicine2010，，8： | 1 |
| 12 | The control of vascular integrity by endothelial cell junctions:molecular basis and pathological implications显示文摘 | Elisabetta Dejana Elisabeth Tournier-Lasserve Brant M Weinstein | 2009 | Developmental Cell2009，16，2： | 1 |
| 13 | Variation in agronomic characteristics and seed oil composition of new oilseed crops in central Italy 显示文摘 | Luciana G A Elisabetta M Giusefiana C | 1997 | Industrial Crops and Products1997，6，34： | 1 |
| 14 | Fibromodulin, an oxidative stress-sensitive proteoglycan, regulates the fibro- genie response to liver injury in mice显示文摘 | Elisabetta M Yongke L Xiaodong G | 2012 | Gastroenterology2012，142，3： | 1 |
| 15 | Survival of young and older breast cancer patients in Geneva From 1990 to 2001 显示文摘 | Elisabetta R Gerald F Helena M | 2005 | Eur J Cancer2005，41，2： | 1 |
| 16 | Anterior Uveitis Compli- cating Zoledronic Acid Infusion 显示文摘 | Annalisa C Giulio M Elisabetta M | 2009 | Ocular Immunology & Inflam- mation2009，17，： | 1 |
| 17 | Antibiotic resistance of benthic bacteria in fish-farm and control sediments of the Western Mediterranean 显示文摘 | ELISABETTA C LUIGI V ANNA M | 2003 | Aquaculture2003，219，： | 1 |
| 18 | Malignant pro- gression in pleomorphic xanthoastroeytoma: personal ex- perience and review of the literature显示文摘 | Elisabetta M Alberto F Enrico O | 2007 | J Neurological Sciences2007，252，2： | 1 |
| 19 | Anterior Uveitis Compli- cating Zoledronic Acid Infusion 显示文摘 | Annalisa C Giulio M Elisabetta M | 2009 | Ocular Immunology & Inflam- mation2009，17，： | 1 |
| 20 | Total antioxidant capacity in patients with varicoceles显示文摘 | Elisabetta Meucci M D | 2003 | Fertile and Sterility2003，79，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员