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12篇 您的检索式：作者名="Egbase"

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		题名	作者	年代	出处	被引量
	1	Serum oestradiol and progesterone concentrations during prolonged coasting in 15 women at risk of ovarian hyperstimulation syndrome following ovarian stimulation for assisted reproduction treatment 显示文摘	Egbase PE Sharhan MAI Berlingiei P	2000	Hum Reprod2000，15，10：	1
	2	Maternal and perinatal outcomes of multiple pregnancy following IVF-ET显示文摘	Makhseed M Al-Sharhan M Egbase P		0，，：	1
	3	Serum oestradiol and progesterone concentrations during prolonged coasting in 15 women at risk of ovarian hyperstimulation syndrome following ovarian stimulation for assisted reproduction treatment 显示文摘	Egbase PE AL Sharhan M Berlingieri P	2000	Hum Reprod2000，15，7：	1
	4	'Early coasting'in patient with polycystic ovarian syndrome is consistent with good clinical outcome显示文摘	Egbase PE AL-Sharhan M Grudzinskas JG	2002	Hum Reprod2002，17，5：	1
	5	Earlycoasting in patients with polycystic ovarian syndrome isconsistent with good clinical outcome显示文摘	Egbase PE Al-Sharhan M Grudzinskas JG	2002	Hum Re-prod2002，17，5：	1
	6	Early unilateral follicular aspiration compared with coasting for the prevention of severe ovarian hyperstirnulation syndrome; a prospective randomized study显示文摘	Egbase PE Sharhan Mal Grudzinskasl JG	1999	Hum Reprod1999，14，6：	1
	7	Timed unilateral ovarian follicular aspiration prior to administration of human chorionie gonadotrophin for the prevention of severe ovarian hyperstimulation syndrome in in-vitro fertilization: a prospective randomized study 显示文摘	Egbase PE Makhseed M AL Sharhan M	1997	Hum Reprod1997，12，12：	1
	8	Early unilateral follicular aspiration compared with coasting for the prevention of severe ovarian hyperstimulation syndrome: a prospective randomized study显示文摘	Egbase PE Sharhan MA Grudzinskas JG	1999	Hum Reprod1999，14，6：	1
	9	Early coasting in patients with polycystic ovarian syndrome is consistent with good clinical outcome显示文摘	Egbase PE Al Sharhan M Grudzinskas JG		0，，05：	1
	10	Early unilateral follicular aspiration compared with coasting for the prevention of severe ovarian hyperstimulation syndrome:a prospective randomized study显示文摘	Egbase PE Sharhan MA Grudzinskas JG	1999	Hum Reprod1999，14，6：	1
	11	Early coasting' in patient with polycystic ovarian syndrome is consistent with good clinical outcome显示文摘	Egbase PE AL-Sharhan M Grudzinskas JG	2002	Hum Reprod2002，17，5：	1
	12	Chemistry-led investigations into the mode of action of NAMPT activators,resulting in the discovery of non-pyridyl class NAMPT activators显示文摘The cofactor nicotinamide adenine dinucleotide(NAD+)plays a key role in a wide range of physiological processes and maintaining or enhancing NAD+levels is an established approach to enhancing healthy aging.Recently,several classes of nicotinamide phosphoribosyl transferase(NAMPT)activators have been shown to increase NAD+levels in vitro and in vivo and to demonstrate beneficial effects in animal models.The best validated of these compounds are structurally related to known urea-type NAMPT inhibitors,however the basis for the switch from inhibitory activity to activation is not well understood.Here we report an evaluation of the structure activity relationships of NAMPT activators by designing,synthesising and testing compounds from other NAMPT ligand chemotypes and mimetics of putative phosphoribosylated adducts of known activators.The results of these studies led us to hypothesise that these activators act via a through-water interaction in the NAMPT active site,resulting in the design of the first known urea-class NAMPT activator that does not utilise a pyridine-like warhead,which shows similar or greater activity as a NAMPT activator in biochemical and cellular assays relative to known analogues.	Siyuan Tang Miguel Garzon Sanz Oliver Smith Andreas Krämer Daniel Egbase Paul W.Caton Stefan Knapp Sam Butterworth	2023	Acta Pharmaceutica Sinica B2023，13，2：	0

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