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| 1 | Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist显示文摘AIM To investigate the impact of physical frailty on risk of hospitalisation in cirrhotic patients on the liver transplant waitlist.METHODS Cirrhotics listed for liver transplantation at a single centre underwent frailty assessments using the Fried Frailty Index, consisting of grip strength, gait speed, exhaustion, weight loss, and physical activity. Clinical and biochemical data including MELD score as collected at the time of assessment. The primary outcome was number of hospitalised days per year; secondary outcomes included incidence of infection. Univariable and multivariable analysis was performed using negative binomial regression to associate baseline parameters including frailty with clinical outcomes and estimated incidence rate ratios(IRR). RESULTS Of 587 cirrhotics, 64% were male, median age(interquartile range) was 60(53-64) years and MELD score was 15(12-18). Median Fried Frailty Index was 2(1-3); 31.6% were classified as frail(fried frailty ≥ 3). During 12 mo of follow-up, 43% required at least 1hospitalisation; 38% of which involved major infection.107/184(58%) frail and 142/399(36%) non-frail patients were hospitalised at least once(P < 0.001). In univariable analysis, Fried Frailty Index was associated with total hospitalisation days per year(IRR = 1.51,95%CI: 1.28-1.77; P ≤ 0.001), which remained significant on multivariable analysis after adjustment for MELD, albumin, and gender(IRR for frailty of 1.21,95%CI: 1.02-1.44; P = 0.03). Incidence of infection was not influenced by frailty.CONCLUSION In cirrhotics on the liver transplant waitlist, physical frailty is a significant predictor of hospitalisation and total hospitalised days per year, independent of liver disease severity. | Marie Sinclair Eduard Poltavskiy Jennifer L Dodge Jennifer C Lai | 2017 | World Journal of Gastroenterology2017，23，5： | 11 |
| 2 | Fabrication approaehes for generaling complex micro- and nanopattems on polymeric surfaces显示文摘 | Aranzazu C Eduard A | 2008 | Chemical Reviews2008，108，3： | 1 |
| 3 | Novel spectral fiber optic sensor based on surface plasmon resonance显示文摘 | Radan SlavAk JirIoA Homola JirIoA C I tyroky A Eduard Brynda | 2001 | Sensors and Actuators2001，，74： | 1 |
| 4 | Pitch-controlled variable- speed wind turbine generation显示文摘 | Eduard Muljadi Butterfield C P | 2001 | IEEE Transactions on Industry Applications2001，37，1： | 1 |
| 5 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014，12，： | 1 |
| 6 | Intestinal Stem Cells in Mammals and Drosophila显示文摘 | Andreu C Eduard B | 2009 | Cell2009，4，： | 1 |
| 7 | A 3-GHz 32-dB CMOS limiting amplifier for SONET OC-48 receivers显示文摘 | Eduard Sackinger Fischer W C | 2000 | IEEE Journal of Solid-State Circuits Conference2000，35，12： | 1 |
| 8 | Pitch-controlled variablespeed wind turbine generation显示文摘 | Muljadi Eduard Butterfield C P | 2001 | IEEE transactions on industry applications2001，37，1： | 1 |
| 9 | Effect of Variable Speed Wind Turbine Generator on Stability of a Weak Grid 显示文摘 | Eduard Muljadi C P Butterfield Brian Parsons | 2007 | IEEE Transactions on Energy Conversion2007，22，1： | 1 |
| 10 | A 3 GHz 32 dB CMOS limiting amplifier for SONET OI2-48 receivers 显示文摘 | Eduard Sackinger Wilhelm C Fischer | 2000 | IEEE Journal of Solid- State Circuits2000，35，12： | 1 |
| 11 | Passive Inter- modulation Due to Self-Heating in Primed TransmissionLines显示文摘 | Eduard R Carlos C Nathan DO | 2011 | IEEE Trans On MTI''2011，59，2： | 1 |
| 12 | Clinical examination and dynamic magnetic resonance imaging in vaginal vault prolapse显示文摘 | Eduard C Wendy M Nreid | 2004 | Obstet Gynecol2004，103，： | 1 |
| 13 | Grey component analysis 显示文摘 | Johan A Westerhuis Eduard P P A Derks Huub C J Hoefsloot | 2007 | Journal of Chemometrics2007，21，10111： | 1 |
| 14 | ESPEN Guide- lines on parenteral nutrition: Hepatology 显示文摘 | MATHIAS P EDUARD C BEMARD C | 2009 | Clin Nutr2009，28，4： | 1 |
| 15 | Designing a Carbon Market That Protects Forests in Developing Countries, Philosophical Transactions: Mathematical 显示文摘 | EDUARD NIESTEN PETER C FRUMHOFF MICHELLE MANION JARED J HARDNER | 2002 | Physical and Engineering Sciences2002，360，1797： | 1 |
| 16 | Effect of variable speed wind turbine generator on stability of a weak grid显示文摘 | Eduard Muljadi Butterfield C P Brian Parsons | 2007 | IEEE Transactions on Energy Conversion2007，22，1： | 1 |
| 17 | High-resolution paleosalinity reconstruction from Laguna dela Lethe, north coastal Cuba, using St, O, and C isotopes显示文摘 | Matthew C Peros Eduard G Reinhardt Henry P Schwarcz | 2007 | Science Direct2007，245，： | 1 |
| 18 | Wildfires and landscape patterns in the Eastern Iberian Peninsula显示文摘 | Francisco L Eduard C Xavier P | 2002 | Landscape Ecology2002，17，8： | 1 |
| 19 | 体力活动与多发性硬化症研究的10大问题显示文摘全世界约有250万人患有多发硬化症(MS),并且发病率有增加趋势。MS是一种中枢神经系统疾病,与多种症状和功能障碍相关。目前一线治疗方法对晚期患者基本无效。越来越多的证据表明体力活动(PA)有益于MS患者,但是大多数MS患者存在PA不足和静坐少动行为。因此,提出了10个研究问题,旨在指导今后有关PA和MS的研究:1)PA是否是一种MS的缓解性治疗行为?2)PA对MS患者有哪些益处?3)什么样的PA处方最适合MS患者?4)MS患者在PA中有哪些安全问题?5)哪些MS患者可以通过PA获得益处?6)哪些变量可以用来解释PA对MS患者的作用?7)有效促进MS患者进行PA的行为干预方法是什么?8)如何将研究成果应用于实际临床工作中?9)静坐少动行为对MS患者有什么影响?10)评价MS患者PA的最佳方法是什么?这些问题对于帮助了解PA对MS患者长期和短期的效果以及开发新方法促进和保持MS患者的PA至关重要,解决这些问题可以大大改善MS患者的生活质量。 | Robert W Motla Yvonne C Learmontha Lara A Piluttia Eduard Gappmaierb Susan Cootec | 2016 | 北京体育大学学报2016，39，3： | 1 |
| 20 | A 3-GHz 32-dB CMOS limiting amplifier for SONET OC-48 receivers 显示文摘 | Sackinger Eduard Fischer Wilhelm C | 2000 | IEEE J Solid-state Circuits2000，35，12： | 1 |
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