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| 1 | Implication of the intestinal microbiome in complications of cirrhosis显示文摘The intestinal microbiome(IM) is altered in patients with cirrhosis,and emerging literature suggests that this impacts on the development of complications.The Pub Med database was searched from January 2000 to May 2015 for studies and review articles on the composition,pathophysiologic effects and therapeutic modulation of the IM in cirrhosis.The following combination of relevant text words and MeS H terms were used,namely intestinal microbiome,microbiota,or dysbiosis,and cirrhosis,encephalopathy,spontaneous bacterial peritonitis,hepatorenal syndrome,variceal bleeding,hepatopulmonary syndrome,portopulmonary hypertension and hepatocellular carcinoma.The search results were evaluated for pertinence to the subject of IM and cirrhosis,as well as for quality of study design.The IM in cirrhosis is characterized by a decreased proportion of Bacteroides and Lactobacilli,and an increased proportion of Enterobacteriaceae compared to healthy controls.Except for alcoholic cirrhosis,the composition of the IM in cirrhosis is not affected by the etiology of the liver disease.The percentage of Enterobacteriaceae increases with worsening liver disease severity and decompensation and is associated with bacteremia,spontaneous bacterial peritonitis and hepatic encephalopathy.Lactulose,rifaximin and Lactobacillus-containing probiotics have been shown to partial y reverse the cirrhosis associated enteric dysbiosis,in conjunction with improvement in encephalopathy.The IM is altered in cirrhosis,and this may contribute to the development of complications associated with end-stage liver disease.Therapies such as lactulose,rifaximin and probiotics may,at least partially,reverse the cirrhosisassociated changes in the IM.This,in turn,may prevent or alleviate the severity of complications. | Mamatha Bhat Bianca M Arendt Venkat Bhat Eberhard L Renner Atul Humar Johane P Allard | 2016 | World Journal of Hepatology2016，8，27： | 13 |
| 2 | Dynamic analysis of flexible manipulators, a literature review 显示文摘 | Dwivedy S K Eberhard P | 2006 | Mechanism and Machine Theory2006，41，7： | 1 |
| 3 | Elastoplastic phenomena in multibody impact dynamics显示文摘 | Schiehlen W Seifried R Eberhard P | 2006 | Computer Methods in Applied Mechanics and Engineering2006，195，： | 1 |
| 4 | Viscoplastic effects occurring in impacts of aluminum and steel bodies and their influence on the coefficient of restitution显示文摘 | Seifried R Minamoto H Eberhard P | 2010 | Journal of Applied Mechanics2010，77，4： | 1 |
| 5 | Requirement of borate cross-linking of cell wall rhamnogalacturonan II for Arabidnpsis growth显示文摘 | O'Neill M A Eberhard S Albersheim P | 2001 | Science2001，294，5543： | 1 |
| 6 | Role of Sodium Intake in the Progression of Chronic Kidney Disease显示文摘 | Eberhard'R Nadezda K Grzegorz P | 2009 | J Ren Nutrit2009，19，1： | 1 |
| 7 | Acoustic echo control -an application of very high-order adaptive filters显示文摘 | Breining C Dseitel P Eberhard H | 1999 | Signal Processing Magazine1999，16，4： | 1 |
| 8 | Requirement of borate cross-linking of cell wall rhamnogalacturonanⅡfor Arabidopsis growth 显示文摘 | O'Neil M A Eberhard S Albersheim P | 2001 | Science2001，294，5543： | 1 |
| 9 | Flexible multibody systems with large deformations and nonlinear structural damping using absolute nodal coordinates显示文摘 | Kübler L Eberhard P Geisler J | 2003 | Nonlinear Dynamics2003，34，1： | 1 |
| 10 | Dynamic analysis of flexible manipulators:a literature review显示文摘 | S K Dwivedy P Eberhard | 2006 | Mechanism and Machine Theory2006，41，7： | 1 |
| 11 | Analysis of the dynamics in microactuators using high-speed cine photomicrography显示文摘 | Christian Rembe Bernd Tibken Eberhard P Hofer | 2001 | Journal of Microelectromechanical System2001，10，1： | 1 |
| 12 | Rigid-elastic modeling of meshing gear wheels in multibody systems显示文摘 | EBRAHIMI S EBERHARD P | 2006 | Multibody System Dynamics2006，16，1： | 1 |
| 13 | Pectic Cell Wall Fragments Regulate Tobacco Thin- Cell- Layer Explant Morphogenesis 显示文摘 | Eberhard S Doubrava N Marfa V Mohnen D Southwick A Darvill A Albersheim P | 1989 | The Plant Cell Online1989，1，8： | 1 |
| 14 | Influence of different field sites on pesticide movement into subsurface drains 显示文摘 | Traub Eberhard U Henachel K P Kordel W | 1995 | Pestic Sci1995，43，2： | 1 |
| 15 | Numerical and experimental investigation of radial impacts on a half-circular plate显示文摘 | SEIERIED R HU B EBERHARD P | 2003 | Multibody System Dynamic2003，9，3： | 1 |
| 16 | Flexible multibody systems with large deformations and nonlinear structural damping using absolute nodal coordinates 显示文摘 | KiJbler L Eberhard P Geisler J | 2003 | Nonlinear Dynamics2003，34，1： | 1 |
| 17 | Simulative and experimental investigation of impacts on gear wheels显示文摘 | Ziegler P Eberhard Peter | 2008 | compute methods in applied mechanics and engineering2008，0197，052： | 1 |
| 18 | Rigid-elastic modeling ofmeshing gear wheels in multibody systems显示文摘 | Ebrahimi S Eberhard P | 2006 | Multi-body System Dynamics2006，16，1： | 1 |
| 19 | Respondingto children's everyday transgressions in Chinese workingclass families显示文摘 | Wang X L Bernas R & Eberhard P | 2008 | Journal of Moral Education2008，37，： | 1 |
| 20 | Simulation of impacts in gear trains using different approaches显示文摘 | Ziegler P Eberhard P Schweizer B | 2006 | Arch Appl Mech2006，76，： | 1 |
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