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| 1 | Pretransplantation α-Fetoprotein Slope and Milan Criteria: Strong Predictors of Hepatocellular Carcinoma Recurrence After Transplantation显示文摘 | Teodora C. Dumitra Sinziana Dumitra Peter P. Metrakos Jeffrey S. Barkun Prosanto Chaudhury Marc Deschênes Steven Paraskevas Mazen Hassanain Jean I. Tchervenkov | 2013 | Transplantation Journal2013，，1： | 2 |
| 2 | Laser Photoacoustic Spectroscopy: Principles, Instrumentation, and Characterization 显示文摘 | Dumitras D C Dutu D C Matei C | 2007 | Journal of Optoelectronics and Advanced Materials2007，9，12： | 1 |
| 3 | Evaluation of ammonia absorption coefficients by photoacoustic spectroscopy for detection of ammonia levels in human breath显示文摘 | DUMITRAS D C DUTU D C MATEI C | 2011 | Laser Physics2011，21，4： | 1 |
| 4 | Particular aspects of endoprosthesis in malignant advanced pharingeal-esoph- ageal stenosis 显示文摘 | Dumitra A Sabau A Maniu D | 2011 | Chirurgia (Bucru)2011，106，3： | 1 |
| 5 | Fast and high performance image subsampling using feedforward neural networks显示文摘 | Dumitras A Kossentini F | 2004 | IEEE Transactions on Image Processing2004，9，4： | 1 |
| 6 | Characterization of a Resonant Photoacoustic Cell Using the Acoustic Transmission Line Model显示文摘 | CRISTESCU S DUMITRAS DAN C DUTU DORU C | 2000 | Proceedings of SPIE2000，4068，： | 1 |
| 7 | The prognostic significance of arterial blood pressure in liver cirrhosis显示文摘 | Stanciu L | 1995 | Rom J Intern Med1995，33，34： | 1 |
| 8 | Characterization of a resonant photoacoustic cell using the acoustic transmission line model 显示文摘 | CRISTESCU S DUMITRAS DAN C DUTU DORU C | 2000 | Proceedings of SPIE2000，4068，： | 1 |
| 9 | Angular map driven snakes with application to object shape description in color images 显示文摘 | Dumitras A Venetsanopoulos N A | 2001 | IEEE Transactions on Image Processing2001，10，12： | 1 |
| 10 | Angular map-driven snakes with application to object shape description in color images 显示文摘 | Dumitras A Venetsanopoulos A N | 2001 | IEEE Transactions on Image Processing2001，10，12： | 1 |
| 11 | Gastric and gall bladder emptying of a mixed meal are not coordinated in liver cirrhosis--a simultaneous sonographic study显示文摘 | Acalovschi M Dumitra? cu DL Csakany I | 1997 | Gut1997，40，3： | 1 |
| 12 | Frequent deletions and down- regulation of micro - RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia 显示文摘 | Colin GA Dumitra CD SMmizu M | 2002 | Proc Natl Acad Sci USA2002，99，15： | 1 |
| 13 | Pretransplantation alphmfetoprotein slope and milan criteria: strong predictors of hepatocellular carcinoma recurrence after transplantation显示文摘 | Dumitra TC Dumitra S Metrakos PP | 2013 | Transplantation2013，95，1： | 1 |
| 14 | Angular map-driven snakes with application to object shape description in color images显示文摘 | DUMITRAS A VENETSANOPOULOS A N | 2001 | IEEE Transactions on Image Processing2001，10，： | 1 |
| 15 | McGill Brisbane Symptom Score for patients with resectable pancreatic head adenocarcinoma显示文摘AIM:To evaluate the ability of the McGill Brisbane Symptom Score(MBSS)to predict survival in resectable pancreatic head adenocarcinoma(PHA)patients.METHODS:All PHA patients(n=83)undergoing pancreaticoduodenectomy at the McGill University Health Center,Quebec between 1/2001-1/2010 were evaluated.Data related to patient and cancer characteristics,MBSS variables,and treatment were collected;univariable and multivariable survival analyses were performed.We obtained complete follow-up until February 2011 in all patients through the database of the provincial health insurance plan of Quebec.The unique health insurance numbers of these patients were used to retrieve information from this database which captures all billable clinical encounters,and ensures 100%actual survival data.RESULTS:Median survival was 23 mo overall:45 mo for patients with low MBSS,17 mo for high MBSS(P=0.005).At twelve months survival was 83.3%(95%CI:66.6-92.1)vs 58.1%(95%CI:42.1-71.2)in those with low vs high MBSS,and24 mo survival was 63.8%(95%CI:45.9-77.1)and 34.0%(95%CI:20.2-48.2)respectively.In the multivariate Cox model(stratified by chemotherapy),after addition of clinically meaningful covariates,MBSS was the variable with the strongest association with survival(HR=2.63;P=0.001).Adjuvant chemotherapy interacted with MBSS category such that only high MBSS patients accrued a benefit.In univariate analysis we found a lower mortality in high MBSS but not low MBSS patients receiving adjuvant chemotherapy.This interaction variable,on Cox model,resulted in an adjusted mortality HR for the high MBSS(compared to low MBSS)of 4.14(95%CI:1.48-11.64)without chemotherapy and 2.11(95%CI:1.06-4.17)with chemotherapy.CONCLUSION:The MBSS is a simple prognostic tool for resectable PHA.Preoperative categorization of patients according to the MBSS allows effective stratification of patients to guide therapy. | Mohammed H Jamal Suhail A R Doi A James Moser Sinziana Dumitra Jad abou Khalil Eve Simoneau Prosanto Chaudhury Adedayo A Onitilo Peter Metrakos Jeffrey S Barkun | 2014 | World Journal of Gastroenterology2014，20，34： | 1 |
| 16 | The advantages of retropancreatic vascular dissection for pancreatic head cancer with portal/superior mesenteric vein invasion:posterior approach pancreatico-duodenectomy technique and the mesopancreas theory显示文摘 | Moldovan SC Moldovan AM Dumitra(ae)cu T | 2012 | Chirurgia(Bucur)2012，107，5： | 1 |
| 17 | Technical factors involved in parathyroid surgery显示文摘 | Dumitras M Strambu V Radu PA et a/ | 2015 | Chirurgia (Bucur)2015，110，5： | 1 |
| 18 | CO2 Laser Ablation of Biological Tissue显示文摘 | DUMITRAS D C DORU C A DUTU C E | 1998 | SPIE1998，3405，： | 1 |
| 19 | CA19-9/胆红素比值联合MBSS系统评分对胰腺癌长期生存情况的预测显示文摘背景胰腺癌是恶性度较高的恶性肿瘤,然而目前尚无能较好预测可切除及不可切除胰腺癌长期生存率的方法。MBSS系统评分(McGillBrisbaneSymptomScore,MBSS)是一种基于症状(体重丢失、疼痛、黄疸、吸烟)的预测系统,研究表明这种预测系统对可切除及不可切除的胰腺癌的长期生存进行较为可靠的预测,评分过高往往提示预后不佳。另外CA19-9及CA19—9/胆红素因与胰头癌的临床特征相关,也曾被作为一种预测指标,但究竟何种预测方式更确切。 | Sinziana Dumitra Mohammad H.Jamal Jad Aboukhalil 张伟 耿小平 | 2014 | 肝胆外科杂志2014，22，3： | 0 |
| 20 | Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma显示文摘Loss of function of the von Hippel-Lindau(VHL)tumor suppressor gene is a hallmark of clear cell renal cell carcinoma(ccRCC).The importance of heterogeneity in the loss of this tumor suppressor has been under reported.To study the impact of intratumoral VHL heterogeneity observed in human ccRCC,we engineered VHL gene deletion in four RCC models,including a new primary tumor cell line derived from an aggressive metastatic case.The VHL gene-deleted(VHL-KO)cells underwent epithelial-to-mesenchymal transition(EMT)and exhibited increased motility but diminished proliferation and tumorigenicity compared to the parental VHL-expressing(VHL+)cells.Renal tumors with either VHL+or VHL-KO cells alone exhibit minimal metastatic potential.Combined tumors displayed rampant lung metastases,highlighting a novel cooperative metastatic mechanism.The poorly proliferative VHL-KO cells stimulated the proliferation,EMT,and motility of neighboring VHL+cells.Periostin(POSTN),a soluble protein overexpressed and secreted by VHL non-expressing(VHL−)cells,promoted metastasis by enhancing the motility of VHL-WT cells and facilitating tumor cell vascular escape.Genetic deletion or antibody blockade of POSTN dramatically suppressed lung metastases in our preclinical models.This work supports a new strategy to halt the progression of ccRCC by disrupting the critical metastatic crosstalk between heterogeneous cell populations within a tumor. | Junhui Hu Ping Tan Moe Ishihara Nicholas ABayley Shiruyeh Schokrpur Jeremy GReynoso Yangjun Zhang Raymond JLim Camelia Dumitras Lu Yang Steven MDubinett Parmjit SJat Jacques Van Snick Jiaoti Huang Arnold IChin Robert MPrins Thomas GGraeber Hua Xu Lily Wu | 2023 | Signal Transduction and Targeted Therapy2023，8，5： | 0 |
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