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1篇 您的检索式:作者名="Duane D.Hall"
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1A Ca^(2+) cycling defect connects insulin resistance and heart failure显示文摘In a recent study published in Life Metabolism,Quan et al.reported that intracellular Ca^(2+)dysregulation in cardiomyocyte can be both a cause and an effect of cardiac insulin resistance that ultimately leads to diabetic cardiomyopathy.Numerous epidemiologic studies across several decades indicate that insulin-resistant states such as diabetes and obesity are risk factors for congestive heart failure independent of common cardiovascular disease factors such as hypertension and coronary artery diseases[1,2].On the other hand,there is evidence that heart failure itself causes the onset and development of insulin resistance[3].Restoring normal cardiac output in advanced heart failure patients with left ventricular assistance devices improves insulin sensitivity and cardiac metabolism[4].Qian Shi Duane D.Hall Long-Sheng Song 2022Life Metabolism2022,1,1:0
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