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| 1 | Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus显示文摘 | Dolff S Abdulahad WH Westra J | 2011 | Arthritis Res Ther2011，13，5： | 1 |
| 2 | Urinary T cells in active lupus nephritis show an effector memory phenotype显示文摘 | Dolff S Abdulahad WH van Dijk MC | | 0，，11： | 1 |
| 3 | Urinary CD8+ T-cell counts discriminate between active and inactive lupus nephritis显示文摘 | Dolff S Abdulahad WH Arends S | | 0，，01： | 1 |
| 4 | Disturbed Th1,Th2,Th17and T(reg)balance in patients with systemic lupuserythematosus显示文摘 | Dolff S Bijl M Huitema MG | 2011 | Clin Immunol2011，141，2： | 1 |
| 5 | Increased expression of costimulatory markers CD134 and CD80 on interleukin-17 producing T cells in patients with systemic lupus erythematosus显示文摘 | Dolff S Quandt D Wilde B | | 0，，04： | 1 |
| 6 | Disturbed Tbl,Th2,Thl7 and T (reg) balance in patientswith systemic lupus erythematosus显示文摘 | Dolff S Bijl M Huitema MG | 2011 | Clin lmmunol2011，141，2： | 1 |
| 7 | CD134 expression on CD4^ + T cells is associated with nephritis and disease aetivity in patients with systemic lupus erythematosus 显示文摘 | Patschan S Dolff S Kribben A | 2006 | Clin Exp Immunol2006，145，2： | 1 |
| 8 | CD134 expression on CD4+ T ceils is associated with nephritis and disease activity in patients with systemic lupus erythematosus显示文摘 | Patschan S Dolff S Kribben A | 2006 | Clin Exp Immunol2006，145，2： | 1 |
| 9 | Regulators of B-cell activity in SLE: a better target for treatment than B-cell depletion? 显示文摘 | Dolff S Abdulahad W Bijl M | 2009 | Lupus2009，18，7： | 1 |
| 10 | Urinary od8+ t-cellcounts discriminate between active and inactive lupus nephritis 显示文摘 | Dolff S Abdulahad WH Arends S | 2013 | Arthritis Res Ther2013，15，1： | 1 |
| 11 | Repaglinide in the management of new-onset diabetes mellitus after renal transplantation显示文摘 | Türk T Pietruck F Dolff S | 2006 | Am J Transplant2006，6，： | 1 |
| 12 | Increased expression of costimulatory markers CD134 and CD80 on interleukin-17 producing T cells in patients with systemic lupus erythematosus 显示文摘 | Dolff S Quandt D Wilde B | 2010 | Arthritis Res Ther2010，12，4： | 1 |
| 13 | A Multipathogen Bile Sample-based PCR Assay Can Guide Empirical Antimicrobial Strategies in Cholestatic Liver Diseases显示文摘Background and objectives:Polymerase chain reaction(PCR)techniques provide rapid detection of pathogens.This pilot study evaluated the diagnostic utility and clinical impact of multiplex real-time PCR(mRT-PCR,SeptiFast)vs.conventional microbial culture(CMC)in bile samples of patients with chronic cholestatic liver diseases(cCLDs),endoscopic retrograde cholangio-pancreatography(ERCP),and peri-interventional-antimicrobial-prophylaxis(pAP).Methods:We prospectively collected bile samples from 26 patients for microbiological analysis by CMC and mRT-PCR.Concordance of the results of both methods was determined by Krippendorff's alpha(α)for inter-rater reliability and the Jaccard index of similarity.Results:mRT-PCR_(bile)and CMC_(bile)results were concordant for only Candida albicans(α=0.8406;Jaccard index=0.8181).mRT-PCR_(bile)detected pathogens in 8/8 cases(100%),CMC_(bile)in 7/8(87.5%),and CMCblood in 5/8(62.5%)with clinical signs of infection.mRTPCR_(bile),CMC_(bile),and CMCblood had identical detection results in 3/8(37.5%)with clinical signs of infection(two Klebsiella spp.and one Enterococcus faecium).The total pathogen count was significantly higher with mRT-PCR_(bile)than with CMC_(bile)(62 vs.31;χ^(2)=30.031,p<0.001).However,pathogens detected by mRT-PCR_(bile)were more often susceptible to pAP according to the patient infection/colonization history(PI/CH)and surveillance data for antibiotic resistance in our clinic(DARC).Pathogens identified by mRT-PC_(Rbile)and resistant to pAP by PI/CH and DARC were likely to be clinically relevant.Conclusions:mRT-PCR in conjunction with CMCs for bile analysis increased diagnostic sensitivity and may benefit infection management in patients with cholestatic diseases.Implementation of mRT-PCR in a bile sample-based diagnostic routine can support more rapid and targeted use of antimicrobial agents in cCLD-patients undergoing ERCP and reduce the rate/length of unnecessary administration of broad-spectrum antibiotics. | Michael Jahn Mustafa KÖzçürümez Sebastian Dolff Hana Rohn Dominik Heider Alexander Dechêne Ali Canbay Peter M.Rath Antonios Katsounas | 2022 | Journal of Clinical and Translational Hepatology2022，10，5： | 1 |
| 14 | Increased expres-sion of costimulatory markers CD134 and CD80 oninterleukin-17 producing T cells in patients withsystemic lupus erythematosus 显示文摘 | Dolff S?Quandt D Wilde B | 2010 | Arthritis Res T-her2010，12，4： | 1 |
| 15 | Urinary T cells in active lupus nephritis show an effector memory phenotype 显示文摘 | Dolff S Abdulahad W H van Dijk M C | 2010 | Ann Rheum Dis2010，69，11： | 1 |
| 16 | Treatment of lupus nephritis显示文摘 | Dolff S Berden JH Bijl M | | 0，，6： | 1 |
| 17 | Urinary CD8+ T -cell counts discriminate between active and inactive lupus nephritis 显示文摘 | Dolff S Abdulahad WH Arends S | 2013 | Arthritis res ther2013，15，1： | 1 |
| 18 | Disturbed Thl , Th2, Th 17 and T(reg)balance in patients with systemic lupus erythematosus 显示文摘 | Dolff S Bijl M Huitema MG | 2011 | Clin immunol2011，141，2： | 1 |
| 19 | Incresed expression ofcostimulatory marker CD134 and CD80 on interleukin-17 producing T cells in patients with systemic lupus erythematosus显示文摘 | Dolff S Quandt D | 2010 | Arthritis Res Ther2010，12，： | 1 |
| 20 | Repaglinide in the management of new-onset diabetes mellitus after renal transplantation显示文摘 | TURK T PIETRUCK F DOLFF S | 2006 | Am J Transplant2006，6，4： | 1 |
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