4篇
您的检索式：作者名="Dimitrios Rigopoulos"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 甲变色显示文摘分析发生甲变色的可能因素:系统性疾病、皮肤病、系统和局部用药、应用美容制品及某些习惯等。甲变色发生在甲半月,多是内部因素引起,甲变色如与远端甲皱襞相一致,则以外因为主。五颜六色的甲颜色改变给临床医师提供了正确诊断的线索。 | Dimitrios Rigopoulos Anestis Prantsidis 张汝芝 | 2005 | 临床皮肤科杂志2005，34，1： | 3 |
| 2 | Increased levels of circulating platelet-derived microparticles in psoriasis:Possible implications for the associated cardiovascular risk显示文摘AIM To evaluate platelet activation markers in psoriasis patients, compared to controls, and investigate their association with the inflammatory burden of psoriasis.METHODS Forty psoriatic patients without cardiovascular disease,and 12 healthy controls were subjected to measurement of baseline platelet CD62 P, CD63 and CD42 b expression, platelet-leukocyte complexes, i.e., platelet-monocyte complexes(PMC), platelet-neutrophil complexes(PNC) and platelet-lymphocyte complexes, and concentrations of platelet-derived microparticles(PMPs) using flow cytometry. Both larger-size(0.5-0.9 μm) and smallersize(< 0.5 μm) PMPs were determined. Serum interleukin(IL)-12 and IL-17 levels were also measured by enzyme-linked immunosorbent assay. The severity of psoriasis was evaluated by the Psoriasis Area Severity Index(PASI).RESULTS PMP concentrations were significantly higher in psoriasis patients than controls [mean±standard error of mean(SEM): 22±5/μL vs 11±6/μL; P=0.018), for both smaller-size(10±2/μL vs 4±2/μL; P=0.033) and larger-size(12±3/μL vs 6±4/μL; P=0.014) PMPs. Platelet CD62 P, CD63 and CD42 b expression and circulating PMC and PNC were similar between the two groups. Lower circulating PLC were observed in psoriasis patients compared to controls(mean±SEM: 16%±3% vs 23%±6%; P=0.047). Larger-size PMPs were related with IL-12 levels(P<0.001) and smaller-size PMPs with both IL-12 and IL-17 levels(P<0.001). Total PMPs also correlated with IL-12(P<0.001). CD63 expression was positively correlated with both IL-12 and IL-17(P<0.05). Increased PASI score was associated with increased levels of larger-size PMPs(r=0.45; P=0.011) and increased CD63 expression(r=0.47; P<0.01).CONCLUSION PMPs, known to be predictive of cardiovascular outcomes, are increased in psoriasis patients, and associated with high inflammatory disease burden. Enhanced platelet activation may be the missing link leading to cardiovascular events in psoriatic patients. | Evangelia Papadavid Konstantina Diamanti Aris Spathis Maria Varoudi Ioanna Andreadou Kostas Gravanis Kostas Theodoropoulos Petros Karakitsos John Lekakis Dimitrios Rigopoulos Ignatios Ikonomidis | 2016 | World Journal of Cardiology2016，8，11： | 2 |
| 3 | Similarities in coronary function and myocardial deformation between psoriasis and coronary artery disease: the role of oxidative stress and inflammation显示文摘 | Ignatios Ikonomidis George Makavos Evangelia Papadavid Maria Varoudi Ioanna Andreadou Kostas Gravanis Kostas Theodoropoulos George Pavlidis Helen Triantafyllidi John Parissis Ioannis Paraskevaidis Dimitrios Rigopoulos John Lekakis | 2014 | Canadian Journal of Cardiology2014，，： | 1 |
| 4 | 女性甲床变色1例显示文摘60岁左右女性,指甲变色4个月。患者报告说,她扣纽扣时有轻微的困难,变色的指甲时常让她感到尴尬,以至于经常在人前有意识地藏起双手。查体可见双手十指甲床上有弥漫性紫癜性红斑(指甲色素沉积),伴有甲床与甲板脱离(甲床剥离症,图1),趾甲没有临床表现。手掌和脚掌均出现皮肤脱屑,一直延伸到手/足背和指/趾尖。头皮上有明显的弥漫性脱发。除此以外,患者没有皮肤或其他系统的其他症状或体征。 | Stamatios Gregoriou Eftychia Platsidaki Polytimi Sidiropoulou Dimitrios Rigopoulos 钟睿琦(译) 马飞(校) | 2022 | 英国医学杂志中文版2022，25，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员