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您的检索式：作者名="Devanand B. Shinde"
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| 1 | Synthesis, docking and ADMET prediction of novel 5-((5-substituted-1-H-1,2,4-triazol-3-yl) methyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine as antifungal agents显示文摘A novel series of 5-((5-substituted-1H-1,2,4-triazol-3-yl)methyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridines 5(a–i) has been synthesized from thienopyridine hydrazide, substituted aromatic nitriles using 4-dimethylaminopyridine(DMAP) as a catalyst under microwave irradiation and evaluated for their in vitro antifungal activity. Compound 5g is found to be more potent against Candida albicans when compared with miconazole. Docking study of the newly synthesized compounds was performed, and results showed good binding mode in the active site of fungal enzyme P450 cytochrome lanosterol 14 ademethylase. ADMET properties of synthesized compounds were also analyzed and showed good drug like properties. The results of in vitro antifungal activity, docking study and ADMET prediction revealed that the synthesized compounds have potential antifungal activity and can be further optimized and developed as a lead compound. | Jaiprakash N. Sangshetti Firoz A. Kalam Khan Rashmi S. Chouthe Manoj G. Damale Devanand B. Shinde | 2014 | Chinese Chemical Letters2014，25，7： | 6 |
| 2 | Sulphamic Acid (H2NSO3H)-Catalyzed Multicomponent Reaction of β-Naphthol: An Expeditious Synthesis of Amidoalkyl Naphthols显示文摘Sulphamic 酸(H2NSO3H ) 被发现是为 -naphthol, 的 multicomponent 冷凝作用反应的有效催化剂芳香的醛和脲或酰胺到在好收益负担得起相应 -amidoalkyl--naphthols。这个新过程的显著特征是高变换,短反应时间,干净反应侧面并且简单试验性并且病情的检查过程。 | NAGAWADE, Rahul R. SHINDE, Devanand B. | 2007 | Chinese Journal of Chemistry2007，25，11： | 6 |
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