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4篇 您的检索式:作者名="Demirdal B"
    题名 作者 年代 出处 被引量
1Lamivudine resistance mutations in patients infected with hepatitis B virus genotype D显示文摘AIM: To determine the distribution of viral genotypes for primary or acquired lamivudine resistance. METHODS: A total of 283 patients with chronic hepatitis B virus (HBV) infection (245 patients with chronic hepatitis B and 38 inactive hepatitis B surface antigen carriers) were included in the study. The HBV geno-type was determined by using quantitative real-time polymerase chain reaction and sequence analysis, and tyrosine-methionine-aspartate-aspartate (YMDD) motif mutations were determined using the reverse transcriptase hybridization method. RESULTS: Lamivudine resistance was determined in a total of 25 (10.7%) chronic hepatitis B patients. Eight subjects (4%) had primary resistance to lamivudine, and 17 (53.1%) had secondary resistance to lamivudine. Genotype D, which was isolated from 267 of the patients with chronic HBV infection, was the dominant genotype in Turkey. CONCLUSION: Identification of YMDD motif mutations should have a positive impact on the selection of proper antiviral medication for patients, even for those who are nucleoside nave.Orhan Yιldιz Bilgehan Aygen Nese Demirtürk Tuna Demirdal Dilara Inan Taner Yιldιrmak Arzu Kantürk Ediz Tütüncü Hepatitis B Study Group 2011World Journal of Gastroenterology2011,17,45:3
2Apolipoprotein A5 polymorphisms in Turkish population:association with serum lipid profile and risk of ischemic stroke显示文摘Can Demird(o)(g)sen B (s)ahin E Türkano(g)lu (o)z(c)elik A 2012Molecular Biology Reports2012,39,10:1
3Direct borohydride fuel cell: main issues met by the membrane-eletrodes-assembly and potential solutions 显示文摘Demird U B 2007Journal of Power Sources2007,172,2:1
4Olefin-based synthetic-drilling fluids volumetric behavior under downhole conditions显示文摘Demirdal B Cunha J C 2009SPEDrilling& Completion2009,24,2:1
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