6篇
您的检索式：作者名="Deepak Ramanathan"
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| 1 | Current concepts in total femoral replacement显示文摘Total femoral replacement(TFR) is a salvage arthroplasty procedure used as an alternative to lower limb amputation. Since its initial description in the mid-20^(th) century, this procedure has been used in a variety of oncologic and non-oncologic indications. The most compelling advantage of TFR is the achievement of immediate fixation which permits early mobilization. It is anticipated that TFR will be increasingly performed as the rate of revision arthroplasty rises worldwide. The existing literature is mainly composed of a rather heterogeneous mix of retrospective case series and a wide assortment of case reports. Numerous TFR prostheses are currently available and the surgeon must understand the unique implications of each implant design. Long-term functional outcomes are dependent on adherence to proper technique and an appropriate physical therapy program for postoperative rehabilitation. Revision TFR is mainly performed for periprosthetic infection and the severe femoral bone loss associated with aseptic revisions. Depending on the likelihood of attaining infection clearance, it may sometimes be advisable to proceed directly to hip disarticulation without attempting salvage of the TFR. Other reported complications of TFR include hip joint instability, limb length discrepancy, device failure, component loosening, patellar maltracking and delayed wound healing. Further research is needed to better characterize the long-term functional outcomes and complications associated with this complex procedure. | Deepak Ramanathan Marcelo BP Siqueira Alison K Klika Carlos A Higuera Wael K Barsoum Michael J Joyce | 2015 | World Journal of Orthopedics2015，6，11： | 6 |
| 2 | Role of negative pressure wound therapy in total hip and knee arthroplasty显示文摘Negative-pressure wound therapy(NPWT) has been a successful modality of wound management which is in widespread use in several surgical fields. The main mechanisms of action thought to play a role in enhancing wound healing and preventing surgical site infection are macrodeformation and microdeformation of the wound bed, fluid removal, and stabilization of the wound environment. Due to the devastating consequences of infection in the setting of joint arthroplasty, there has been some interest in the use of NPWT following total hip arthroplasty and total knee arthroplasty. However, there is still a scarcity of data reporting on the use of NPWT within this field and most studies are limited by small sample sizes, high variability of clinical settings and end-points. There is little evidence to support the use of NPWT as an adjunctive treatment for surgical wound drainage, and for this reason surgical intervention should not be delayed when indicated. The prophylactic use of NPWT after arthroplasty in patients that are at high risk for postoperative wound drainage appears to have the strongest clinical evidence. Several clinical trialsincluding single-use NPWT devices for this purpose are currently in progress and this may soon be incorporated in clinical guidelines as a mean to prevent periprosthetic joint infections. | Marcelo BP Siqueira Deepak Ramanathan Alison K Klika Carlos A Higuera Wael K Barsoum | 2016 | World Journal of Orthopedics2016，7，1： | 5 |
| 3 | Biosynthesis, purification and characterization of silver nanoparticles using Escherichia coli显示文摘 | Sangiliyandi Gurunathan Kalimuthu Kalishwaralal Ramanathan Vaidyanathan Deepak Venkataraman Sureshbabu Ram Kumar Pandian Jeyaraj Muniyandi Nellaiah Hariharan Soo Hyun Eom | 2009 | Colloids and Surfaces B: Biointerfaces2009，，1： | 2 |
| 4 | 显示文摘 | Ramanathan S Karthikeyan R Deepak K V | 2006 | Journal of Materials Science & Technology2006，22，5： | 1 |
| 5 | Hot deformation behavior of 2124 A1 alloy显示文摘 | RAMANATHAN S KARTHIKEYAN R DEEPAK V | 2006 | Journal of material science and technology2006，22，61： | 1 |
| 6 | 显示文摘 | Ramanathan S Karthikeyan R Deepak K V | 2006 | Journal of Materials Science & Technology2006，22，5： | 1 |
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