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| 1 | Zircon U-Pb SHRIMP ages of the Taiping (calc-alkaline)-Huangshan (alkaline) composite intrusion:Constraints on Mesozoic lithospheric thinning of the southeastern Yangtze Craton,China显示文摘The Taiping-Huangshan composite intrusion is a unique complex with characteristics changing from calc-alkaline (Taiping intrusion) to alkaline (Huangshan intrusion). Huangshan intrusion samples show a spectacular tetrad effect in their REE distribution patterns as well as non-CHARAC (charge-and radius-controlled) trace element behavior, indicating a highly evolved late-stage magma component. This composite intrusion provides a rare opportunity to investigate the variance of tectonic setting and lithospheric thinning of the southeastern Yangtze Craton in late Mesozoic era. Zircon SHRIMP U-Pb analyses yield an emplacement age of 140.6±1.2 Ma for the Taiping intrusion, and ages of 127.7±1.3, 125.7±1.4, 125.1±1.5, and 125.2±5.5 Ma for four samples from the Huangshan intrusion respectively. The ages for four different phases of the Huangshan intrusion agree within their small analytical errors, indicating that the emplacement was in a short time. The Taiping and Huangshan intrusions are intimately associated, but there is about 15 Ma interval between their intrusion, and the magma characters change from calc-alkaline to alkaline without transition. This probably corresponds to lithospheric thinning of the southeastern Yangtze Craton. This event possibly happened from about 141 Ma (the emplacement age of the Taiping intrusion), to 128 Ma (start of emplacement of the Huangshan intrusion). The thinning mechanism is dominantly delamination. | XUE HuaiMin WANG YingGeng MA Fang WANG Cheng WAN DeEn ZUO YanLong | 2009 | Science China Earth Sciences2009,52,11: | 28 |
| 2 | Influence of rolling friction on single spout fluidized bed simulation显示文摘In this paper we study the effect of rolling friction on the dynamics in a single spout fluidized bed using Discrete Element Method (DEM) coupled to Computational Fluid Dynamics (CFD). In a first step we neglect rolling friction and show that the results delivered by the open source CFD-DEM framework applied in this study agree with previous simulations documented in literature. In a second step we include a rolling friction sub-model in order to investigate the effect of particle non-sphericity. The influence of particle-particle as well as particle-wall rolling friction on the flow in single spout fluidized bed is studied separately. Adequate rolling friction model parameters are obtained using first principle DEM simulations and data from literature. Finally, we demonstrate the importance of correct modelling of rolling friction for coupled CFD-DEM simulations of spout fluidized beds. We show that simulation results can be improved significantly when applying a rolling friction model, and that experimental data from literature obtained with Positron Emission Particle Tracking (PEPT) technique can be satisfactorily reproduced. | Christoph Goniva Christoph Kloss Niels G. Deen Johannes A.M.Kuipers Stefan Pirker | 2012 | Particuology2012,10,5: | 18 |
| 3 | Biliary microlithiasis,sludge,crystals, microcrystallization,and usefulness of assessment of nucleation time显示文摘BACKGROUND:The process of microcrystallization,its sequel and the assessment of nucleation time is ignored.This systematic review aimed to highlight the importance of biliary microlithiasis,sludge,and crystals,and their association with gallstones,unexplained biliary pain,idiopathic pancreatitis, and sphincter of Oddi dysfunction.DATA SOURCES:Three reviewers performed a literature search of the PubMed database.Key words used were'biliary microlithiasis','biliary sludge','bile crystals','cholesterol crystallisation','bile microscopy','microcrystal formation of bile','cholesterol monohydrate crystals','nucleation time of cholesterol','gallstone formation','sphincter of Oddi dysfunction'and'idiopathic pancreatitis'.Additional articles were sourced from references within the studies from the PubMed search.RESULTS:We found that biliary microcrystals account for almost all patients with gallstone disease,7%to 79%with idiopathic pancreatitis,83%with unexplained biliary pain, and 25%to 60%with altered biliary and pancreatic sphincter function.Overall,the detection of biliary microcrystals in gallstone disease has a sensitivity ranging from 55%to 87%and a specificity of 100%.In idiopathic pancreatitis,the presence of microcrystals ranges from 47%to 90%.A nucleation time less than 10 days in hepatic bile or ultra-filtered gallbladder bile has a specificity of 100%for cholesterol gallstone disease.CONCLUSIONS:Biliary crystals are associated with gallstone disease,idiopathic pancreatitis,sphincter of Oddi dysfunction, unexplained biliary pain,and post-cholecystectomy biliary pain.Pathways of cholesterol super-saturation,crystallisation, and gallstone formation have been described with scientificsupport.Bile microscopy is a useful method to detect microcrystals and the assessment of nucleation time is a good method of predicting the risk of cholesterol crystallisation. | Vasitha Abeysuriya Kemal I Deen Navarathne MM Navarathne | 2010 | Hepatobiliary & Pancreatic Diseases International2010,9,3: | 13 |
| 4 | Petrogenetic contrastive studies on the Mesozoic early stage ore-bearing and late stage ore-barren granites from the southern Anhui Province显示文摘Yanshanian magmatisms are intensive in the southern Anhui Province and can be divided into early(152–137 Ma)and late(136–122 Ma) stages. A Yanshanian granitic zone was found to crop out along Qingshan to Changgai areas in the Tunxi district in Field investigation which has a genetic link with molybdenum multiple metal mineralization. To be a representative syenitic granite in the southern Anhui Province, the Huangshan pluton has not been found so far to have any genetic link with mineralization. Zircon LA-ICP-MS dating indicate that the four granitic bodies from the Qingshan-Changgai zone have concurrent formed ages from 140±4 to 141±2 Ma, belonging to the Yanshanian early stage magmatism. However, the Huangshan granite is dated to be 129±2 Ma, belonging to the Yanshanian late stage magmatism. The Qingshan-Changgai granites show high SiO2 and K2 O contents, low P2O5 contents and middle Al2O3 contents and are high-K calc-alkaline series metaluminum I-type granite. These rocks are characterized by enrichments in the large ion lithophile elements and light rare earth elements(REE), depletions in the high field-strength elements, and middle degree negative anomalies of Eu, geochemical features of arc or continent crustal derived magma affinities. These rocks have 87Sr/86Sr(t) ratios from 0.7120 to 0.7125, εNd(t) values from.7.24 to.4.38 and zircon εHf(t) values of.4.4 to 6.7, similar to that of the coeval ore-bearing granodiorites in the southern Anhui Province. Integrated geochemical studies indicate that the Yanshanian ore-bearing granodiorites were formed by partial melting of the Meso-Neoproterozoic accreted thickened low crust. Meanwhile, the Qingshan-Changgai granites were formed through a AFC process of plagioclase+amphibole+Shangxi Group of magmas that formed the ore-bearing granodiorites. The Huangshan granites are characterized by high SiO2 and K2 O contents, moderate Al2O3 contents, seagull shape REE distributed pattern and distinct Eu negative abnormities. Comparing with the Qingshan-Changgai granites, the Huangshan granites show more Ba, Sr, P,and Ti negative abnormities with no Nb and Ta depletions and are high-K calc-alkaline series metaluminum A-type granite. εHf(t)values of the Huangshan granites are from.6.6 to.1.2, similar to that of the early stage ore-bearing granodiorites, indicating that they were also formed by anatexis of the Meso-Neoproterozoic accreted crust, but their magma sources might be residual granulitic crust which ever underwent Yanshanian early stage I-type intermediate-acid magma extraction. Comparing studies on the two stages granites indicate that the early stage granites derived from a relative thickened low crust under a lower temperature condition. Their magma sources were Meso-Neoproterozoic accreted crust which enriched in ore-forming materials and further became more enriched through processes of magma AFC evolution. However, the late stage A-type granites originated from relative shallow crust under a higher temperature condition. Their magma source was depleted in ore-forming materials due to the early stage magma extraction and thus had weak ore-forming capacity. From early to late stage, the magmatisms tectonic setting translated from post-orogenic to anorogenic and the later corresponded to a back-arc extensional setting as increase of the slab subducted angle of the Paleo-Pacific plate. | YAN Jun HOU TianJie WANG AiGuo WANG DeEn ZHANG DingYuan WENG WangFei LIU JianMin LIU XiaoQiang LI QuanZhong | 2017 | Science China Earth Sciences2017,60,11: | 9 |
| 5 | Influence of liquid layers on energy absorption during particle impact显示文摘The influence of the thickness of a covering liquid layer and its viscosity as well as the impact velocity on energy loss during the normal impact on a flat steel wall of spherical granules with a liquid layer was studied. Free-fall experiments were performed to obtain the restitution coefficient of elastic–plastic Al2O3 granules by impact on the liquid layer, using aqueous solutions of hydroxypropyl methylcellulose with different concentrations for variation of viscosity (1–300 mPa s). In the presence of a liquid layer, increase of liquid viscosity decreases the restitution coefficient and the minimum thickness of the liquid layer at which the granule sticks to the wall. The measured restitution coefficients were compared with experiments performed without liquid layer. In contrast to the dry restitution coefficient, due to viscous losses at lower impact velocity, higher energy dissipation was obtained. A rational explanation for the effects obtained was given by results of numerically solved force and energy balances for a granule impact on a liquid layer on the wall. The model takes into account forces acting on the granule including viscous, surface tension, capillary, contact, drag, buoyancy and gravitational forces. Good agreement between simulations and experiments has been achieved. | Sergiy Antonyuk Stefan Heinrich Niels Deen Hans Kuipers | 2009 | Particuology2009,7,4: | 5 |
| 6 | Discrete particle modeling of granular temperature distribution in a bubbling fluidized bed显示文摘The discrete hard sphere particle model (DPM) is applied in this work to study numerically the distributions of particle and bubble granular temperatures in a bubbling fluidized bed. The dimensions of the bed and other parameters are set to correspond to those of Müller et al. (2008). Various drag models and operational parameters are investigated to find their influence on particle and bubble granular temperatures. Various inlet superficial gas velocities are used in this work to obtain their effect on flow characteristics. It is found that the superficial gas velocity has the most important effect on granular temperatures including bubble granular temperature, particle translational granular temperature and particle rotational granular temperature. The drag force model affects more seriously the large scale variables such as the bubble granular temperature. Restitution coefficient influences all granular temperatures to some degree. Simulation results are compared with experimental results by Müller et al. (2008) showing reasonable agreement. | Yurong He Tianyu Wang Niels Deen Martin van Sint Annaland Hans Kuipers Dongsheng Wen | 2012 | Particuology2012,10,4: | 4 |
| 7 | Coefficient of restitution for particles impacting on wet surfaces: An improved experimental approach显示文摘 | B. Cunger V. Salikov S. Heinrich S. Antonyuk V.S. Sutkar N.G. Deen J.A.M. Kuipers | 2016 | Particuology2016,14,2: | 4 |
| 8 | Microbiology of gallbladder bile in uncomplicated symptomatic cholelithiasis显示文摘BACKGROUND:Few studies have assessed microflora and their antibiotic sensitivity in normal bile and lithogenic bile with different types of gallstones. METHODS:We performed a case control study of 70 bile samples(35 cholesterol and 35 pigment stones from 51 females and 19 males,aged 21-72 years with a median age of 37 years)from patients who underwent laparoscopic cholecystectomy for uncomplicated cholelithiasis,and 20 controls(14 females and 6 males,aged 33-70 years with a median age of 38 years)who underwent laparotomy and had no gallbladder stone shown by ultrasound scan.The bile samples were aerobically cultured to assess microflora and their antibiotic susceptibility.The procedures were undertaken under sterile conditions. RESULTS:Thirty-eight(54%)of the 70 patients with gallstones had bacterial isolates.Nine isolates(26%)were from cholesterol stone-containing bile and 29 isolates (82%)from pigment stone-containing bile(P=0.01,t test). Twenty-eight of these 38(74%)bile samples were shown positive only after enrichment in brain heart infusion medium(BHI)(P=0.02,t test).The overall bacterial isolates from bile samples revealed E.coli predominantly,followed by P.aeruginosa,Enterococcus spp.,Klebsiella spp.and S. epidermidis.There were no bacterial isolates in the bile of controls after either direct inoculation or enrichment in BHI.CONCLUSIONS:Bacterial isolates were found in pigment stone-containing bile.Non-lithogenic bile revealed no bacteria,showing an association between gallstone formation and the presence of bacteria in bile.Antibiotic sensitivity patterns of isolated organisms were similar irrespective of the type of stone. | Vasitha Abeysuriya Kemal Ismil Deen Tamara Wijesuriya Sujatha Senadera Salgado | 2008 | Hepatobiliary & Pancreatic Diseases International2008,7,6: | 3 |
| 9 | 基于自参考的高精度红外点衍射干涉仪研制(英文)显示文摘介绍了一种结构简单紧凑、可用于高精度实时相位波前测量的红外点衍射干涉仪,采用类迈克耳孙的光学结构,并结合低通小孔滤波,同时使用窗口傅里叶变换的方法解调单幅离轴载波条纹。与传统波前测量技术相比,所提出的准共光路的光学系统结构有效地抑制了系统像差及外部环境干扰等对测量结果的影响,实现高精度和高分辨率的波前探测。实验结果表明,该方法能够实现高精度的相位测量,且其重复精度达到了纳米量级。 | 杨朋千 Stefan Hippler Casey Deen Wolfgang Brandner Sarah Kendrew 缪洁 张艳丽 朱健强(指导) | 2013 | 中国激光2013,40,5: | 3 |
| 10 | Borescopic particle image velocimetry in bubbling gas-solid fluidized beds显示文摘In this work, the borescopic particle image velocimetry (BPIV) technique was applied to a bubbling gas-solid fluidized bed, and the results were compared with published positron emission particle tracking (PEPT) measurement data. Before performing the experiments, the sensitivity of the BPIV results to the illumination power, light reflectivity of the particles, and location of the borescope was also investigated. The BPIV and PEPT results were in fair agreement;however, some discrepancies were observed.The difference between the two sets of results were mainly caused by the intrusiveness of BPIV, the fact that the local solids volume fraction was not accounted for in the BPIV analysis, and the intrinsic differences of these two methods. Therefore, measurement of the local solids volume fraction with the borescope is highly recommended for further development of the BPIV method, which will also enable measureme nt of the local solids mass fluxes in side dense gas-solid fluidized beds. | M. Banaei R. Dellaert N.G. Deen J.A.M. Kuipers M. van Sint Annaland | 2019 | Particuology2019,17,2: | 2 |
| 11 | Colorectal cancer in the young,many questions,few answers显示文摘At a time where the incidence of colorectal cancer,a disease predominantly of developed nations,is showing a decline in those 50 years of age and older,data from the West is showing a rising incidence of this cancer in young individuals.Central to this has been the 75% increase in rectal cancer incidence in the last four decades.Furthermore,predictive data based on mathematical modelling indicates a 124 percent rise in the incidence of rectal cancer by the year 2030-a statistic that calls for collective global thought and action.While predominance of colorectal cancer(CRC) is likely to be in that part of the large bowel distal to the splenic flexure,which makes flexible sigmoidoscopic examination an ideal screening tool,the cost and benefit of mass screening in young people remain unknown.In countries where the incidence of young CRC is as high as 35% to 50%,the available data do not seem to indicate that the disease in young people is one of high red meat consuming nations only.Improvement in our understanding of genetic pathways in the aetiology of CRC,chiefly of the MSI,CIN and CIMP pathway,supports the notion that up to 30% of CRC is genetic,and may reflect a familial trait or environmentally induced changes.However,a number of other germline and somatic mutations,some of which remain unidentified,may play a role in the genesis of this cancer and stand in the way of a clear understanding of CRC in the young.Clinically,a proportion of young persons with CRC die early after curative surgery,presumably from aggressive tumour biology,compared with the majority in whom survival after operation will remain unchanged for five years or greater.The challenge in the future will be to determine,by genetic fingerprinting or otherwise,those at risk of developing CRC and the determinants of survival in those who develop CRC.Ultimately,prevention and early detection,just like for those over 50 years with CRC,will determine the outcome of CRC in young persons.At present,aside from those with an established familial tendency,there is no consensus on screening young persons who may be at risk.However,increasing awareness of this cancer in the young and the established benefit of prevention in older persons,must be a message that should be communicated with medical students,primary health care personnel and first contact doctors.The latter constitutes a formidable challenge. | Kemal I Deen Hiroshi Silva Raeed Deen Pramodh C Chandrasinghe | 2016 | World Journal of Gastrointestinal Oncology2016,8,6: | 2 |
| 12 | Numerical simulation of gas-liquid-solid flows using a combined front tracking and discrete particle method显示文摘 | Annaland M V S Deen N G Kuipers J A M | 2005 | Chemical Engineering Science2005,60,11: | 1 |
| 13 | Review of discrete particle modeling of fluidized beds 显示文摘 | DEEN N G van SINT ANNALAND M van der HOEF M A | 2007 | Chemical Engineering Science2007,62,1820: | 1 |
| 14 | Graphene wrapped MnOz- nanostmctures as effective and stable electrode materials for capacitive deionization desalination technology显示文摘 | Deen A G Barakat N A M Kim H Y | 2014 | Desalination2014,344,: | 1 |
| 15 | Relative biological effectiveness of ^125Ⅰ sources in a murine braehytherapy model 显示文摘 | De Silva VF Gutin PH Deen DF | 1984 | Int J Radia Oncol Biol Phys1984,10,: | 1 |
| 16 | Cigarette smoke extract affects functional activity of MRP1 in bronchial epithelial cells 显示文摘 | van der Deen M de Vries EG Visserman H | 2007 | J Biochem Mol Toxicol2007,21,5: | 1 |
| 17 | Nerve root sleeve injections in patients with failed back surgery syndrome:A comparison of three solutions显示文摘 | Devulder J Deene P De Laat M | | 0,,: | 1 |
| 18 | Nasojejunal feeding versus feeding jejunostomy after upper gastrointestinal surgery显示文摘 | Ranjithatharsini M Deen KI Kumarage SK | 2014 | Sri Lanka Journal of Surgery2014,32,2: | 1 |
| 19 | Killing of brain tumor cells by hypoxia-responsive element mediated expression of BAX 显示文摘 | Wang J Hu L Lin CS Lamborn KR Deen DF | 1999 | Neoplasia1999,1,5: | 1 |
| 20 | Numerical simulation of the dynamic flow behavior in a bubble column: a study of closures for turbulence and interface forces 显示文摘 | Zhang D Deen N G Kuipers J A M | 2006 | Chemical Engineering Science2006,6,: | 1 |