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| 1 | 从附睾到卵子:CRISP蛋白在哺乳动物受精过程中的作用显示文摘哺乳动物的受精过程涉及精卵结合的很多步骤,是一个非常复杂的过程,其分了机制亟待阐明。此篇综述主要论述了CRISP(富含半胱氨酸的分泌蛋白)作为模型分子在哺乳动物受精过程中的价值。大量的体外实验和基因敲出模型研究显示,附睾内的CRISP1以两种不同的亲和力结合于精子表面,参与精子获能、精子-透明带结合、精卵融合的调控。这些研究成果可以延伸至人类。我们住研究中发现,人类具有与啮齿类同源的CRISP(hCRISP1),同样参与受精过样。CRISP家族的其他成员(睾丸内CRISP2、附挈内CRISP3—4、射精时的CRISP3)也参与了精卵结合的过程,提示同源分子间的相互协同有助于受精的成功。另外,我们的研究显示,CRISP蛋白伴随精子穿越男性及女性生殖管道的全过程。我们推测CRISP不仅参与了受精过程,而且可能成为不育和避孕研究的新靶点。 | Vanina G Da Ros Mariana Weigel Munoz Maria A Battistone Nicolas G Brukman Guillermo Carvajal Ludmila Curci Matlas D Gomez-Elias Debora J Cohen Patricia S Cuasnicu | 2015 | Asian Journal of Andrology2015，17，5： | 5 |
| 2 | Vairetal and processingef fects on the volatile profile of Auatralian olive oils显示文摘 | Debora T Paul D P Danny R B | 2004 | Food Chemistry2004，，8： | 1 |
| 3 | Autohydrolysis of agricultural by-products for the production of xylo-oligosaccharides 显示文摘 | Debora N Ebringerova A Montane D | 2007 | Carbohydrate Polymers2007，69，1： | 1 |
| 4 | Role of endothelin-1 in neovascularation of ovarian carcinoma 显示文摘 | Debora S Valeriana D C Maria R N | 2000 | Am J Pathol2000，157，5： | 1 |
| 5 | Postoperative rehabilitation following total shouloler arthroplasty显示文摘 | Debora D Richard J | 1988 | Orthop Clin North Am1988，29，3： | 1 |
| 6 | Postoperative rehabilitation following total shoulder arthroplasty显示文摘 | Debora D Richard J | 1998 | Orthopedic Clinics of North America1998，29，3： | 1 |
| 7 | Improving virgin olive oil quality by means of innovative extracting biotech- nologies 显示文摘 | ALFONSO R TOMMASO G DEBORA D | 2003 | J Agric Food Chem2003，51，9： | 1 |
| 8 | Titania nanosheets(TNS)/sulfonated poly(ether ether ketone)(SPEEK) nanocomposite proton exchange membranes for fuel cells显示文摘 | Debora M Alessandra D'Epifanio Enrico T | 2010 | Chemistry of Materials Article2010，22，3： | 1 |
| 9 | A covalent organic/inorganic hybrid proton exchange polymeric membrane:synthesis and characterization显示文摘 | M Luisa D V Debora M | 2005 | Polymer2005，46，： | 1 |
| 10 | Optimization of Alkaline Transesterification of Soybean Oil and Castor Oil for Biodiesel Production 显示文摘 | Debora D O Marco D L | 2005 | Applied Biochem Biotechnol2005，，： | 1 |
| 11 | A simple new route to covalent organic/inorganic hybrid proton exchange polymeric membranes 显示文摘 | Luisa Di Vona M Debora Marani Cadia D'Ottavi | 2006 | Chem Mater2006，18，： | 1 |
| 12 | Postoperative rehabilitation following total shoulder arthroplasty显示文摘 | Debora D Brown Richard J Friedman | 1998 | J Orthop Clin North1998，29，3： | 1 |
| 13 | Fate of oxidized triglycerides during refining of seed oils显示文摘 | TOMMASO G FRANCESCO C DEBORA D | 2003 | Food Chem2003，51，16： | 1 |
| 14 | Postoperative rehabilitation following total shoulder arthroplasty显示文摘 | Debora D Richard J | 1988 | Orthopedic Clinics of North America1988，29，3： | 1 |
| 15 | Proteomic analysis of cerebrospinal fluid from multiple sclerosis patients显示文摘 | Debora D Jean-Paul N | 2004 | Proteomics2004，4，： | 1 |
| 16 | Postoperative Rehabilitation Following Total Shoulder Arthroplasty显示文摘 | Debora D Richard J | 1998 | Orthopedic Clinics of North America1998，29，3： | 1 |
| 17 | Ambi- ent temperature kinetic assessment of biogas production from co-digestion of horse and cow dung显示文摘 | YUSUF M O L DEBORA A OGHENERUONA D E | 2011 | Journal of Agricultural Engineering Research2011，57，3： | 1 |
| 18 | Proteomic analysis of cerebrospinal fluid from multiple sclerosis patients 显示文摘 | Debora D Jean - Paul N | 2004 | Proteomics2004，4，： | 1 |
| 19 | Sodium - calcium exchange: A molecular perspective 显示文摘 | Kenneth D Philipson Debora A Nicoll | 2000 | Annu Rev Physiol2000，62，： | 1 |
| 20 | Association of UBP 1 to ribonucleoprotein complexes is regulated by interaction with the trypanosome ortholog of the human multifunctional P 32 protein显示文摘 | Alejandro Cassola María Albertina Romaniuk Debora Primrose Gabriela Cervini Iván D’Orso Alberto Carlos Frasch | 2015 | Molecular Microbiology2015，，： | 1 |
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