|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Understanding cancer stem cell heterogeneity and plasticity显示文摘异质是在 vitro 并且在 vivo 的哺乳动物的房间的一个无所不在的特征。甚至在最好的文化条件下面的老鼠和人的胚胎的干细胞是异构的象部分承诺的房间一样包含 pluripotent,这最近被认识到。在成年器官的体的干细胞也是异构的,包含有不同再生能力的自我更新的细胞的许多 subpopulations。成年干细胞的区分的子孙也保留能被许多试验性的途径导致的重要发展粘性。象正常干细胞一样,最近的数据建议癌症干细胞(CSC ) 同样显示重要 phenotypic 和功能的异质,并且 CSC 子孙能表明多样的粘性。这里,我在肿瘤开发和前进的上下文讨论 CSC 异质和粘性,并且由与正常干细胞开发作比较。对癌症房间粘性的欣赏必要到在肿瘤的仅仅 tumorigenic 子集需要到的更早的概念的修订被指向。由理解在 CSC 和他们的区分的子孙之间的相互关系,我们能希望开发能阻止能成立一个新肿瘤和远转移的肿瘤房间变体的出现的更好治疗学的政体。 | Dean G Tang | 2012 | Cell Research2012，22，3： | 37 |
| 2 | The spectrum of neuromyelitis optica显示文摘 | Dean M Wingerchuk Vanda A Lennon Claudia F Lucchinetti Sean J Pittock Brian G Weinshenker | 2007 | Lancet Neurology2007，，9： | 3 |
| 3 | The Importance of Medial Support in Locked Plating of Proximal Humerus Fractures显示文摘 | Michael J Gardner Yoram Weil Joseph U Barker Bryan T Kelly David L Helfet Dean G Lorich | 2007 | Journal of Orthopaedic Trauma2007，，3： | 2 |
| 4 | Extrahepatic metastasis of hepatocellular carcinoma to the paravertebral muscle:A case report显示文摘Identification of extrahepatic metastases(EHM) of hepatocellular carcinoma(HCC) has been paradoxically increasing due to an increase in the survival of HCC patients. However, metastasis of HCC to the skeletal muscle tissue is extremely rare. We describe a unique case of HCC metastasizing to the paravertebral muscle. A 55-year-old man with a history of hepatitis B cirrhosis underwent partial liver resection with complete removal of HCC. Three months later, a computed tomography(CT) scan showed intrahepatic recurrence. The tumors were treated with yttrium-90 microspheres, transcatheter arterial chemoembolization, and sorafenib. Six months later, a CT scan showed an enhancing lesion of the left paravertebral muscle that on biopsy were consistent with metastatic HCC. The tumor was treated with stereotactic hypo-fractionated imageguided radiation therapy(SHFRT). A follow-up scan 3 mo post-radiotherapy revealed a stable appearance of the paravertebral muscle metastasis. Because of the progression in the intrahepatic tumors, the patient was treated with capecitabine, which was changed to dasatinib 6 mo later. The patient passed away three years after the primary surgical resection. Management of EHM poses an extreme challenge. This is the first case of HCC with EHM to the paravertebral muscle in which stability of disease was achieved using SHFRT. This case highlights the importance of early detection of hepatitis B viral infection and initiation of anti-viral therapy to decrease recurrence of HCC and prevent EHM. | Kazuhiro Takahashi Krishna G Putchakayala Mohamed Safwan Dean Y Kim | 2017 | World Journal of Hepatology2017，9，22： | 2 |
| 5 | The human ATP-binding cassette (ABC) transporter super-family显示文摘 | Dean M Hamon Y Chimini G | 2001 | J Lipid Res2001，42，7： | 1 |
| 6 | Non-ionlc, poly(ethylene oxide)-based surfactants as intercalants/dispersants/exfoliants for poly(propylene)-clay nanocomposites 显示文摘 | Mead G Dean K Edmond L | 2006 | Macromol Mater Eng2006，291，1： | 1 |
| 7 | Cellular immune responses induced in cattle by heterologous prime-boost vaccination using recombinant viruses and bacille Calmette-Guerin显示文摘 | Vordermeier HM Rhodes SG Dean G | 2004 | Immunology2004，112，： | 1 |
| 8 | Creep and physical aging of PVC: dependence on stress and temperature显示文摘 | Read B E Dean G D Tomlins P E | 1994 | Journal of Non-CrystaUine Solids1994，，： | 1 |
| 9 | The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation 显示文摘 | Dean JL Sully G Clark AR | 2004 | Cell Signal2004，6，10： | 1 |
| 10 | Influence of a Commercial Yeast Supplement on the in Vitro Ruminal Fermentation显示文摘 | Martin S A Nisbet D J Dean R G | 1989 | Nutr Rep Int1989，40，： | 1 |
| 11 | Increased CNS levels of apolipoprotein D in schizophrenic and bipolar subjects:implications for the pathophysiology of psychiatric disorders显示文摘 | Thomas E Dean B Pavey G | 2001 | Proc Natl Acad Sci USA2001，98，7： | 1 |
| 12 | Revision and psychometric testing of the City of Hope Quality of Life-Ostomy Questionnaire显示文摘 | Grant M Ferrell B Dean G | 2004 | Qual Life Res2004，，13： | 1 |
| 13 | Modelling non-linear creep behaviour of an epoxy adhesive显示文摘 | Dean G | 2007 | Intemational Journal of Adhesion and Adhesives2007，27，8： | 1 |
| 14 | Wave field modification by bathymetric anomalies and resulting shoreline changes:a review with recent results显示文摘 | Bender C J Dean R G | | 0，，： | 1 |
| 15 | Iodine content of some New Zealand drinking waters with a note on the contribution from sea spray to the iodine in rain 显示文摘 | Dean G A | 1964 | NZJSci1964，6，： | 1 |
| 16 | What do we want and what do we get from not-for-profit hospitals 显示文摘 | Clement Jan p Smith Dean G Wheeler John R C | 1994 | Hospital & Health Services Administration1994，39，2： | 1 |
| 17 | The human ATP-binding cassette ( ABC ) transporter superfamily 显示文摘 | Dean M Hamon Y Chimini G | 2001 | The Journal Lipid Research2001，427，： | 1 |
| 18 | Retrogade Intramedullarry Nailing of Supracondylar Femoral Fracture显示文摘 | David L Heffct Dean G Lorch | 1998 | Clin Orthop1998，350，： | 1 |
| 19 | Uptake of Pb^2+ and Cu^2+ by novel biopolymers显示文摘 | Deans J R Dixon B G | 1992 | Water Res1992，26，4： | 1 |
| 20 | Removing heavy metals from waste water 显示文摘 | Dean J G Bosqui F L Bermond A | 1972 | Environ Sci Technol1972，6，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员