2篇
您的检索式：作者名="David J.Morgan"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Cold adaptation does not alter ATP homeostasis during cold exposure in Drosophila melanogaster显示文摘In insects and other ectotherms,cold temperatures cause a coma resulting from loss of neuromuscular function,during which ionic and metabolic homeostasis are progressively lost.Cold adaptation improves homeostasis during cold exposure,but the ultimate targets of selection are still an open question.Cold acclimation and adaptation remodels mitochondrial metabolism in insects,suggesting that aerobic energy production during cold exposure could be a target of selection.Here,we test the hypothesis that cold adaptation improves the ability to maintain rates of aerobic energy production during cold exposure by using^(31)P NMR on live flies.Using lines of Drosophila melanogaster artificially selected for fast and slow recovery from a cold coma,we show that cold exposure does not lower ATP levels and that cold adaptation does not alter aerobic ATP production during cold exposure.Cold-hardy and cold-susceptible lines both experienced a brief transition to anaerobic metabolism during cooling,but this was rapidly reversed during cold exposure,suggesting that oxidative phosphorylation was sufficient to meet energy demands below the critical thermal minimum,even in cold-susceptible flies.We thus reject the hypothesis that performance under mild low temperatures is set by aerobic ATP supply limitations in D.melanogaster,excluding oxygen and capacity limitation as a weak link in energy supply.This work suggests that the modulations to mitochondrial metabolism resulting from cold acclimation or adaptation may arise from selection on a biosynthetic product(s)of those pathways rather than selection on ATP supply during cold exposure. | Caroline M.WILLIAMS James R.ROCCA Arthur S.EDISON David B.ALLISON Theodore J.MORGAN Daniel A.HAHN | 2018 | Integrative Zoology2018，13，4： | 0 |
| 2 | The hydrogenation of levulinic acid to γ-valerolactone over Cu–ZrO2 catalysts prepared by a pH-gradient methodology显示文摘A novel pH gradient methodology was used to synthesise a series of Cu–ZrO2 catalysts containing different quantities of Cu and Zr.All of the catalysts were highly selective to the desired product,γ-valerolactone, and are considerably more stable than Cu–ZrO2 catalysts prepared by other co-precipitation methods for this reaction.Characterisation and further investigation of these catalysts by XRD, BET, SEM and XPS provided insight into the nature of the catalytic active site and the physicochemical properties that lead to catalyst stability.We consider the active site to be the interface between Cu/CuOxand ZrOx and that lattice Cu species assist with the dispersion of surface Cu through the promotion of a strong metal support interaction.This enhanced understanding of the active site and roles of lattice and surface Cu will assist with future catalyst design.As such, we conclude that the activity of Cu–ZrO2 catalysts in this reaction is dictated by the quantity of Cu–Zr interface sites. | Igor Orlowski Mark Douthwaite Sarwat Iqbal James S.Hayward Thomas E.Davies Jonathan K.Bartley Peter J.Miedziak Jun Hirayama David J.Morgan David J.Willock Graham J.Hutchings | 2019 | Journal of Energy Chemistry2019，28，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员