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11篇 您的检索式:作者名="David J Webb"
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1Photonic gas sensors exploiting directly the optical properties of hybrid carbon nanotube localized surface plasmon structures显示文摘Weinvestigate the modification of the optical properties of carbon nanotubes(CNTs)resulting from a chemical reaction triggered by the presence of a specific compound(gaseous carbon dioxide(CO_(2)))and show this mechanism has important consequences for chemical sensing.CNTs have attracted significant research interest because they can be functionalized for a particular chemical,yielding a specific physical response which suggests many potential applications in the fields of nanotechnology and sensing.So far,however,utilizing their optical properties for this purpose has proven to be challenging.We demonstrate the use of localized surface plasmons generated on a nanostructured thin film,resembling a large array of nano-wires,to detect changes in the optical properties of the CNTs.Chemical selectivity is demonstrated using CO_(2) in gaseous form at room temperature.The demonstrated methodology results additionally in a new,electrically passive,optical sensing configuration that opens up the possibilities of using CNTs as sensors in hazardous/explosive environments.Thomas Allsop Raz Arif Ron Neal Kyriacos Kalli Vojtěch Kundrát Aleksey Rozhin Phil Culverhouse David J Webb 2016Light(Science & Applications)2016,5,1:3
2Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life.Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant 2022World Journal of Diabetes2022,13,3:2
3Highly sensitive bend sensor based on Bragg grating in eccentric core polymer fiber 显示文摘CHEN Xianfeng ZHANG Chi David J Webb 2010IEEE Photonies Technology Letters(S1041-1135)2010,22,11:1
4Cystatin C improves the detection of mild renal dysfunction in older parients显示文摘O'Riordan Shelagh E Webb Michelle C Stowe Helen J Simpson David E Kandarpa Madhu 2003Ann clin biochem2003,40,23:1
5Gapped BLAST and PSI-BLAST:a new generation of protein database search programs 显示文摘 Stephen F Thomas L M Alejandro A S Jinghui Zhang Zheng Zhang Webb M David J L 1997Nucleic Acids Res1997,25,17:1
6Exploring differential prescribing between anti-epileptic drugs in epilepsy patients with a history of mood disorders显示文摘Ishihara L David J Webb MSc 2010Pharmacoepidemiol Drug Saf2010,19,3:1
7COX-2 selective inhibitors—important lessons learned显示文摘Simon RJ Maxwell David J Webb 2005The Lancet2005,,9458:1
8Randomized trial of CD8+ T-cell depletion in the prevention of graft-versus-host disease associated with donor lymphocyte infusion显示文摘Robert J Soiffer Edwin P Alyea Ephraim Hochberg Catherine Wu Christine Canning Bijal Parikh David Zahrieh Iain Webb Joseph Antin Jerome Ritz 2002Biology of Blood and Marrow Transplantation2002,,11:1
9Distal microcirculatory protection during percutaneous coronary intervention in a- cute ST-segment elevation myocardial infarction 显示文摘Stone GW Webb J David A 2005JAMA2005,293,9:1
10为规范处方行为开个处方——一些医学生并不具备熟练开处方的能力显示文摘每年的这个时候,新分配来的医生上岗了,老的担心又出现了——他们受过良好的培训了吗?特别令人担忧的是:他们在临床药物治疗和开处方方面是否受过合格的培训?我们认为培训未必合格。Jeffrey K Aronson Graeme Henderson David J Webb Michael D Rawlins 肖月(译) 2007英国医学杂志中文版2007,10,1:0
11内皮素受体拮抗剂:前景光明显示文摘肺动脉高压是逐渐进展和恶化的疾病,以肺内小动脉血管收缩伴相应的结构改变为特点。特发性肺动脉高压比较罕见[发病率为(1~2)/100万],主要影响育龄期女性。继发原因包括HIV感染、结缔组织疾病和门静脉高压。对于肺动脉高压WHO功能分级Ⅱ-Ⅳ级的患者,治疗包括类前列腺素药和西地那非。20年前首次发现内皮素-1.其被认为是一种有力的缩血管物质.并具有促有丝分裂和促纤维化作用。Neeraj Dhaun David J Webb 徐绍鹏(译) 2008世界临床医学2008,2,6:0
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