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| 1 | Diagnostic accuracy of endoscopic ultrasound in pancreatic neuroendocrine tumors: A systematic review and meta analysis显示文摘AIM: To detect pancreatic neuroendocrine tumors (PNETs) has been varied. This study is undertaken to evaluate the accuracy of endoscopic ultrasound (EUS) in detecting PNETs.METHODS: Only EUS studies confirmed by surgery or appropriate follow-up were selected. Articles were searched in Medline, Ovid journals, Medline nonindexed citations, and Cochrane Central Register of Controlled Trials and Database of Systematic Reviews. Pooling was conducted by both fixed and random effects model). RESULTS: Initial search identified 2610 reference articles, of these 140 relevant articles were selected and reviewed. Data was extracted from 13 studies (n = 456) which met the inclusion criteria. Pooled sensitivity of EUS in detecting a PNETs was 87.2% (95%CI: 82.2-91.2). EUS had a pooled specificity of 98.0% (95%CI: 94.3-99.6). The positive likelihood ratio of EUS was 11.1 (95%CI: 5.34-22.8) and negative likelihood ratio was 0.17 (95%CI: 0.13-0.24). The diagnostic odds ratio, the odds of having anatomic PNETs in positive as compared to negative EUS studies was 94.7 (95%CI: 37.9-236.1). Begg-Mazumdar bias indicator for publication bias gave a Kendall's tau value of 0.31 (P = 0.16), indication no publication bias. The P for χ2 heterogeneity for all the pooled accuracy estimates was > 0.10. CONCLUSION: EUS has excellent sensitivity and specificity to detect PNETs. EUS should be strongly considered for evaluation of PNETs. | Srinivas R Puli Nikhil Kalva Matthew L Bechtold Smitha R Pamulaparthy Micheal D Cashman Norman C Estes Richard H Pearl Fritz-Henry Volmar Sonu Dillon Michael F Shekleton David Forcione | 2013 | World Journal of Gastroenterology2013，19，23： | 14 |
| 2 | Hepatic expression and cellular distribution of the glucose transporter family显示文摘Glucose and other carbohydrates are transported into cells using members of a family of integral membrane glucose transporter (GLUT) molecules. To date 14 members of this family, also called the solute carrier 2A proteins have been identified which are divided on the basis of transport characteristics and sequence similarities into several families (Classes 1 to 3). The expression of these different receptor subtypes varies between different species, tissues and cellular subtypes and each has differential sensitivities to stimuli such as insulin. The liver is a contributor to metabolic carbohydrate homeostasis and is a major site for synthesis, storage and redistribution of carbohydrates. Situations in which the balance of glucose homeostasis is upset such as diabetes or the metabolic syndrome can lead metabolic disturbances that drive chronic organ damage and failure, confirming the importance of understanding the molecular regulation of hepatic glucose homeostasis. There is a considerable literature describing the expression and function of receptors that regulate glucose uptake and release by hepatocytes, the most import cells in glucose regulation and glycogen storage. However there is less appreciation of the roles of GLUTs expressed by non parenchymal cell types within the liver, all of which require carbohydrate to function. A better understanding of the detailed cellular distribution of GLUTs in human liver tissue may shed light on mechanisms underlying disease pathogenesis. This review summarises the available literature on hepatocellular expression of GLUTs in health and disease and highlights areas where further investigation is required. | Sumera Karim David H Adams Patricia F Lalor | 2012 | World Journal of Gastroenterology2012，18，46： | 5 |
| 3 | Isolation of angiopoietin-1,a ligand for the TIE2 receptor,by secretion-trap expression cloning 显示文摘 | David S Aldrich T H Johes P F | 1996 | Cell1996，87，7： | 2 |
| 4 | Frostfire:An experimental approach to predicting the climate feedbacks from the changing boreal fire regime显示文摘 | Larry D H Masami F David V S | 2003 | Journal of Geophysical Research2003，108，： | 1 |
| 5 | Modeling electricity auction显示文摘 | Natalia F Nils H F David H | 2002 | The Electricity Journal2002，15，7： | 1 |
| 6 | Engineering a simple, efficient code generator generator 显示文摘 | CHRISTOPER W F DAVID R H TODD A P | 1992 | ACM Letters on Programming Languages and Systems1992，1，3： | 1 |
| 7 | A new approach for outcrop characterization andgeostatistical analysis of a low-sinuosity fluvial-dominated succession using digital outcrop models:Upper Triassic Oukaimeden sandstone formation,central High Atlas,Morocco显示文摘 | Ivan F David H Jonathan R | 2009 | AAPG Bulletin2009，93，6： | 1 |
| 8 | Ramsdellite-MnO2 for lithium batteries: The ramsdellite to spinel transformation显示文摘 | THACKERAY M M ROSSOUW M H GUMMOW R J LILES D C PEARCE K KOCK A D DAVID W I F HULLS S | 1993 | Electrochim Acta1993，38，9： | 1 |
| 9 | LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator显示文摘 | Davide N Mauri Reinhard Ebner Rebecca I Montgomery Kristine D Kochel Timothy C Cheung Guo-Liang Yu Steve Ruben Marianne Murphy Roselyn J Eisenberg Gary H Cohen Patricia G Spear Carl F Ware | 1998 | Immunity1998，，： | 1 |
| 10 | High-pressure methane and carbon dioxide adsorption on dry and moisture-equilibrated Pennsylvanian coals显示文摘 | Krooss B M van Bergen F Gensterblum Y Siemons N Pagnier H J M David P | 2002 | Int J Coal Geol2002，51，2： | 1 |
| 11 | An Integrative Model of Organizational Trust : Past, Present, and Future 显示文摘 | F David Schoorman Roger C Mayer James H Davis | 2007 | The A- cademy of Management Review2007，，： | 1 |
| 12 | The skill content of recent technological change: an empirical exploration 显示文摘 | DAVID H LEVY F MURNANE R J | 2003 | The Quarterly Journal of Economics2003，118，4： | 1 |
| 13 | Kinetic processes of photoeatalytic mineralization of alcohols on metallized titanium dioxide显示文摘 | Chen Jian Ollis David F Rulkens Wire H | 1999 | Water Research1999，33，5： | 1 |
| 14 | New Expandable Hydrogel-Platinum coil hybrid device for aneurysm embolization显示文摘 | Kallmes Naomi H | 2002 | Am J Neuroradiol2002，23，： | 1 |
| 15 | Interlocking Directorates : A Strategy for Reducing Environmental Un - certainty显示文摘 | F David Schoorman Max H Bazerman Robert S Atkin | 1981 | A- cademy of Management1981，6，2： | 1 |
| 16 | CrystallisationKinetics of Novel Branched Poly(ethylene terephthalate) : a Small-angle X-ray Scattering Study显示文摘 | Tracey L H John S F David S | 2006 | Polymer Interna- tional2006，55，： | 1 |
| 17 | The skill content of recent technological change: an empirical exploration 显示文摘 | DAVID H LEVY F MURNANE R J | 2003 | The Quarterly Journal of Economics2003，118，4： | 1 |
| 18 | Motivated Skepticism: Use of Differential Decision Criteria for Preferred and Non - Preferred Conclusions 显示文摘 | Ditto Peter H David F Lopez | 1992 | Journal of Personality and Social Psychology1992，63，4： | 1 |
| 19 | Toward a Stewardship Theory of Management 显示文摘 | DAVID J H SCHOORMAN F D DONALDSON L | 1997 | Academy of Management Review1997，22，1： | 1 |
| 20 | Turnover contagion:how coworkers job embeddedness and job search behaviors influencequitting 显示文摘 | WILL F TERENCE R M DAVID R H | 2009 | Academy of Management Journal2009，，3： | 1 |
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