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| 1 | Multiple levels of regulation of selenoprotein biosynthesis revealed from the analysis of human glioma cell lines显示文摘 | David BM Honglin H Vadim NG | 2000 | Bioehem Pharmacol2000，60，： | 1 |
| 2 | Effect of increasing difficulty in standing balance tasks with visual feedback on postural sway and EMG:complexity and performance显示文摘 | David BM Rafael SS Francisco J | 2012 | Human Movement Science2012，31，： | 1 |
| 3 | A role for vascular endothelial growth factor in acute and resolving lung injury 显示文摘 | David RT Lynne A Ann BM | 2002 | Am J Rcspir Cirt Care Med2002，166，： | 1 |
| 4 | Sexually dimorphic gone expression in the developing mouse gonad 显示文摘 | Douglas BM David CP | 2002 | Gene Expr Patterns2002，2，： | 1 |
| 5 | Endothelin-1 mediates cardiac mast cell degranulation,matrix metalloproteinase activation,and myocardial remodeling in rats显示文摘 | David BM Jason DG Gregory LB | 2004 | J Physiol Heart Circ Physiol2004，287，： | 1 |
| 6 | Thoracic epidural analgesia in cardiac surgery : impact on postoperative morbidity 显示文摘 | David BM Thomas M Hemmerling M | 2008 | Techn Reg Anest Pain Manage2008，12，1： | 1 |
| 7 | Epicardium based left atrial ablation : impact on electromechanical properties 显示文摘 | David S Gianluca BM | 2003 | J Cardiovasc Electrophysiol2003，14，10： | 1 |
| 8 | A role for vascular endothelial growth factor in acute and resolving lung injury显示文摘 | David RT Lynne A Ann BM | 2002 | Am J Respair Crit Care Med2002，166，： | 1 |
| 9 | The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21CIP1/Waf1显示文摘 | Vishwanie BM Peter JM David SL | 2002 | Oncogene2002，21，： | 1 |
| 10 | Economic analysis of influen- za vaccination and antiviral treatment for healthy working adults 显示文摘 | Patrick YL David BM Dennis AC et 81 | 2002 | Arch Intern Med2002，137，： | 1 |
| 11 | A computer aided socket design procedure for above knee prostheses显示文摘 | Richard TM James BM David C | 1992 | J Rehabil Res Dev1992，29，3： | 1 |
| 12 | The academic trauma center is a model for the future trauma and acute care surgeon 显示文摘 | David JC Ernest EM John BM | 2005 | J Trauma2005，58，4： | 1 |
| 13 | Nanosensors and biochips: frontiers in biomolecular diagnostics显示文摘 | Tuan VD CuUum BM David IS | 2001 | Sensors and Actuators B2001，74，： | 1 |
| 14 | The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21CIP1/Waf1显示文摘 | Vishwanie BM Peter JM David SL | 2002 | Oncogene2002，21，39： | 1 |
| 15 | Histopathology of calcineurin inhibitor-induced nephrotoxicity显示文摘 | David RD Iris BM Javier PP | 2000 | Transplantation2000，69，12： | 1 |
| 16 | Induction of the heat shock response in rats modulate heart rat, creatine kinase and plvtein synthesis after subsequent hyperthermic treatment 显示文摘 | Currie RW Ross BM David TA | 1990 | CardioVasc Res1990，24，2： | 1 |
| 17 | The challenge of promoting professionalism through medical ethics and humanities education 显示文摘 | David JD Laurence BM Stephen W | 2013 | Acad Med2013，88，11： | 1 |
| 18 | Aspirin as a promising agent for decreasing incidence of cerebral aneurysm rupture显示文摘 | David MH Kelly BM Robert DB | 2011 | Stroke2011，42，11： | 1 |
| 19 | A role for vascular endothelial growth factor in acute and resolving lung injury显示文摘 | David RT Lynne A Ann BM | 2002 | Am J Respir Cirt Care Med2002，166，： | 1 |
| 20 | Atm deficient zebrafish model reveals conservation of the tumour suppressor function and a role in fertility显示文摘Biallelic loss-of-function variants in ATM (Ataxia Telangiectasia Mutated) cause Ataxia Telangiectasia (AT), a rare disorder associated with cerebellar degeneration and ataxia, cancer predisposition, infertility, growth retardation, etc. ATM is a phosphoinositide 3-kinase-related kinase (PIKK) with a role in DNA repair and maintenance of genome stability. Studying a multisystem genetic disease like AT requires animal models to ascertain its pathogenesis at the level of tissues, organs and the organism. Due to its small size, cheap maintenance, large progeny, rapid development and initial transparency, zebrafish (Danio rerio) is an increasingly popular vertebrate model organism, suitable for genetic modifications and large-scale in vivo therapeutic screens as embryos are chemically permeable to small compounds. Currently, no zebrafish model for AT exists.1 We generated atm knock-outs through CRIPSR-Cas9 mutagenesis. We show that atm conserved its function as a tumour suppressor gene and is involved in gametogenesis and fertility. Therefore, this mutant is of great value for further studies investigating the role of atm in reproduction and tumorigenesis. | Jeroen Vierstraete Charlotte Fieuws David Creytens Jo Van Dorpe Andy Willaert Anne Vral Kathleen BM Claes | 2023 | Genes & Diseases2023，10，2： | 0 |
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