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| 1 | 新肺结核患者中与不依从相关的危险因素以及六个俄罗斯地区的社会支持显示文摘背景:六个俄罗斯地区的结核病服务机构实施的结核病(TB)患者社会支持项目。目的:检出病人不依从治疗的危险因素并评价社会支持的可能影响。方法:回顾研究2003年2~3季度期间登记的涂片阳性和阴性的新结核病人。通过病例——对照研究,包括不依从治疗病人作为病例组、成功治疗病人作为对照组进行的资料分析,采用多变量logistic回归模型分析。结果:共纳入1805例肺结核(PTB)病人。病人不依从治疗的概率为2.3%-6.3%。经多变量分析,不依从治疗的独立相关危险因素有:失业(OR=4.44;95%CI:2.23-8.86),酗酒(OR=1.99;95%CI: 1.04-3.81),无家可归(OR=3.49;95%CI:1.25-9.77)。社会支持降低了不依从结果(OR=0.13;95%CI:0.06-0.28)。该分析控制了年龄、性别、地区、居住地和痰涂片抗酸染色因素的影响。结论:失业、酗酒和无家可归是增加新结核病患者不依从治疗风险的相关因素,相反,社会支持降低了不依从。在俄罗斯为了评估和确定最佳成本——效益的社会支持对改善结核病人治疗结果的作用进一步进行前瞻性随机研究是必须的,尤其在有较高不依从治疗风险的人群。 | W. M. Jakubowiak E. M. Bogorodskaya E. S. Borisov D. I. Danilova E. K. Kourbatova 胡旸(译) 屠德华(校) 张立兴(审) | 2007 | 国际结核病与肺部疾病杂志2007,2,1: | 7 |
| 2 | Pathological changes in the cellular structures of retina and choroidea in the early stages of alloxan-induced diabetes显示文摘AIM To investigate the temporal sequence of pathological changes in the cellular structures of retina and choroidea in the early stages of diabetes in laboratory animals.METHODS Experimental type 1 diabetes was modeled by three intraperitoneal injections of an alloxan solution into 30 male nonlinear rats at 16 wk of age. The 30 th and 60 th days from the final alloxan injection were chosen as the endpoints. Light and electron microscopy and morphometric and immunohistochemical studies were performed on histological slices of eyeballs from experimental animals.RESULTS Diabetic disturbances progressed to 60 d of the experiment. Thus, in the retina, a partial destruction of photoreceptors accompanied by interstitial edema was observed. The morphometric analysis revealed a reduction in the thickness of the retina. A reduction in the number of blood vessels of the choroid with disturbances of the endothelial cells and the vascular walls and a persistent reduction in the number of melanocytes were observed. The number of proliferating Ki-67 positive cells decreased, and the number of macrophages increased with diabetes development.CONCLUSION The starting point in the development of destructive changes involves early reduction in the number of melanocytes of the choroidea and alterations in the retinal pigment epithelium. | Irina Danilova Svetlana Medvedeva Svetlana Shmakova Margarita Chereshneva Alexey Sarapultsev Petr Sarapultsev | 2018 | World Journal of Diabetes2018,9,12: | 6 |
| 3 | Genetics of macrovascular complications in type 2 diabetes显示文摘Type 2 diabetes mellitus(T2DM)is a metabolic disorder that currently affects more than 400 million worldwide and is projected to cause 552 million cases by the year 2030.Long-term vascular complications,such as coronary artery disease,myocardial infarction,stroke,are the leading causes of morbidity and mortality among diabetic patients.The recent advances in genome-wide technologies have given a powerful impetus to the study of risk markers for multifactorial diseases.To date,the role of genetic and epigenetic factors in modulating susceptibility to T2DM and its vascular complications is being successfully studied that provides the accumulation of genomic knowledge.In the future,this will provide an opportunity to reveal the pathogenetic pathways in the development of the disease and allow to predict the macrovascular complications in T2DM patients.This review is focused on the evidence of the role of genetic variants and epigenetic changes in the development of macrovascular pathology in diabetic patients. | Ziravard N Tonyan Yulia A Nasykhova Maria M Danilova Andrey S Glotov | 2021 | World Journal of Diabetes2021,12,8: | 2 |
| 4 | 企业网络营销中的搜索引擎优化(SEO)策略分析显示文摘互联网的普及带来了人们消费模式的变化,网络营销已经成为企业市场营销的一个重要方向。搜索引擎优化是网络营销的一个重要手段,它的主要目的是增加特定关键字的曝光率以增加网站的能见度,进而增加销售的机会。运用好SEO技术对企业开展网络营销实践意义重大。本文着重分析了企业网络营销中搜索引擎优化的相关技术策略。 | Abdulla Aripov Nigmatovich Danilova Anastasiya Mikhaylovna | 2015 | 科教文汇2015,,30: | 2 |
| 5 | The immunoglobulin heavy-chain locus in zebrafish: identification and expression of a previously unknown isotype, immunoglobulin Z 显示文摘 | Danilova N Bussmann J Jekosch K | 2005 | Nat Immunol2005,6,: | 1 |
| 6 | Social support and incentives programme for patients with tuberculosis:experience from the Russian Federation显示文摘 | Jakubowiak WM Bogorodskaya EM Borisov SE Danilova ID Lomakina OB Kourbatova EV | 2007 | Iut J Tuberc Lung Dis2007,11,11: | 1 |
| 7 | Immunoglobulin variable-region diversity in the zebrafish显示文摘 | Danilova N Hohman V S Kim E H | | 0,,01: | 1 |
| 8 | Prevalence of extensively drug-resistant tuberculosis in Vladimir and Orel regions, Russia显示文摘 | Punga VV Jakubowiak WM Danilova ID | 2009 | Int J Tuberc Lung Dis2009,13,10: | 1 |
| 9 | T cells and the thymus in developing zebrafish显示文摘 | DANILOVA N HOHMAN V S SACHER F | 2004 | Dev Comp Immunol2004,28,78: | 1 |
| 10 | P53 family in development 显示文摘 | Danilova N Sakamoto KM Lin S | 2008 | MechDev2008,125,11: | 1 |
| 11 | The immunoglobulin heavy-chain locus in zebrafish: identification and expression of a previously unknown isotype,immunoglobulin Z显示文摘 | Danilova N Bussmann J Jekosch K | 2005 | Nature Immunology2005,6,3: | 1 |
| 12 | Immunoglobuli variable-region diversity in the zebrafish 显示文摘 | Danilova N Hohman V S Kim E H | 2000 | Immunogenetics2000,52,12: | 1 |
| 13 | Investigation of palladium interaction with cerium oxide and its state in catalysts for low-temperature co oxidation显示文摘 | Boronin A I Slavinskaya E M Danilova I G | 2009 | Catal Today2009,144,34: | 1 |
| 14 | Brazzein a small, sweet protein : discovery and physiological overview显示文摘 | Hellekant G Danilova V | 2005 | Chem Senses2005,30,1: | 1 |
| 15 | The immunoglobulin heavy chain locus in zebrafish: identification and expression of a previously unknown isotype, immunoglobulin Z 显示文摘 | DANILOVA N BUSSMANN J JEKOSCH K | 2005 | Nature Immunology2005,6,: | 1 |
| 16 | Preferential activation of the hedgehog pathway by epigenetic modulations in HPV negative HNSCC identified with meta-pathway analysis显示文摘 | Fertig E J Markovic A Danilova LV | 2013 | PLoS One2013,8,78: | 1 |
| 17 | The immunoglobulin heavy-chain locus in zebra-fish:identification and expression of a previously unknown isotype,immunoglobulin Z显示文摘 | Danilova N Bussmann J Jekosch K | 2005 | Nat Immunol2005,6,: | 1 |
| 18 | Heat transfer and two-phase flow of freons in evaporators of refrigerators显示文摘 | DANILOVA G N AZARSKOV V M ZEMSKOV B B | 1986 | Heat Transfer: Soviet Res1986,18,6: | 1 |
| 19 | Role of silica–alumina catalyst texture in the reaction of propane oxidative dehydrogenation in the presence of sulfur dioxide显示文摘 | I G Danilova A S Ivanova | 2000 | Kinetics and Catalysis2000,41,4: | 1 |
| 20 | T cells and the thymus in developing zebrafish显示文摘 | Danilova N Hohman V S Sacher F | 2004 | Dev Comp Immunol2004,8,78: | 1 |