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| 1 | ASTM医疗材料和器械的应用技术与标准显示文摘ASTM国际标准组织F04医疗与外科材料和器械技术委员会为医疗器械原材料、设计、制造和临床应用提供国际标准。这些国际标准涵盖了医疗器械的新兴技术领域,目前只有F04委员会才敢于去涉足新兴技术的标准化,这显示了F04委员会能够跟上技术进步的速度来制定相应的标准,以满足安全需要,支持技术的市场化应用。F04委员会拥有来自30多个国家的1000多名会员,已制定了260多项标准。在包括医师、管理者、学者、研究员、制造商等众多领域专家的努力下,F04已有数十项标准被有关法规引用和在全球应用。本文重点介绍F04委员会的历史沿革、目前进行的诸如磁共振成像技术(MRI)和组织工程医疗产品(TEMPs)新技术标准化活动以及委员会与法律监管机构的合作关系。 | Daniel A. Schultz 刘斐 | 2010 | 药物分析杂志2010，30，7： | 3 |
| 2 | Mediation of transforming growth factor - beta 1 - stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring 显示文摘 | Daniels JT Schultz GS Blalock TD | 2003 | Am J Pathol2003，163，5： | 1 |
| 3 | Mediationof transforming growth factor-beta stimulated matrix contractionby fibroblasts:a role for connective tissue growth factor in con-tractile scarring显示文摘 | DANIELS JT SCHULTZ G S BLALOCK T D | 2003 | Am J Pathol2003，163，5： | 1 |
| 4 | performance auditing in Ohio:a customer service orientation显示文摘 | Daniel E Schultz Jr Richard E Brown | 2003 | The Journal of Government Financial Management2003，，2： | 1 |
| 5 | Mediation of transfor-ming growth factor-beta1 stimulated matrix contraction by fibro-blasts:a role for connective tissue growth factor in contractile scar-ring显示文摘 | Daniels JT Schultz GS Blalock TD | 2003 | Am J Pathol2003，163，5： | 1 |
| 6 | Early markers of reperfusion injury after liver transplantation: association with primary dysfunction显示文摘BACKGROUND:In patients with end-stage liver disease,liver transplantation is the only available curative treatment.Although the outcome and quality of life in the patients have improved over the past decades,primary dys-or nonfunction(PDF/PNF)can occur.Early detection of PDF and PNF is crucial and could lead to individual therapies.This study was designed to identify early markers of reperfusion injury and PDF in liver biopsies taken during the first hour after reperfusion.METHODS:Biopsies from donor livers were prospectively taken as a routine during the first hour after reperfusion.Recipient data,transaminases and outcome were routinely monitored.In total,10 biopsy specimens taken from patients with 90-day mortality and PDF,and patients with long-term survival but without PDF were used for DNA microarrays.Markers that were significantly up-or down-regulated in the microarray were verified using quantitative real-time PCR.RESULTS:Age,indications and lab MELD score were similar in both groups.Peak-transaminases during the first week after transplantation were significantly different in the two groups.In total,20 differentially regulated markers that correlated to PDF were identified using microarray analysis and verified with quantitative real-time PCR.CONCLUSIONS:The markers identified in this study could predict PDF at a very early time point and might point to interventions that ameliorate reperfusion injury and thus prevent PDF.Identification of patients and organs at risk might lead to individualized therapies and could ultimately improve outcome. | Helge Bruns Jan Heil Daniel Schultze Mohammed Al Saeedi Peter Schemmer | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，3： | 1 |
| 7 | Papillary (Chromophil) Renal Cell Carcinoma: Histomorphologic Characteristics and Evaluation of Conventional Pathologic Prognostic Parameters in 62 Cases显示文摘 | Mahul B. Amin Christopher L. Corless Andrew A. Renshaw Satish K. Tickoo James Kubus Daniel S. Schultz | 1997 | The American Journal of Surgical Pathology1997，，： | 1 |
| 8 | Mediation of transforming growth factor-beta (1)-stimulated matrix contraction by fibroblasts:a role for connective tissue growth factor in contractile scarring显示文摘 | Daniels JT Schultz GS Blalock TD | 2003 | Am J Pathol2003，163，5： | 1 |
| 9 | Use of BMD to control hemorrhagic bowel syndrome in swine显示文摘 | Schultz R A Daniels G N | 1984 | Vet Med1984，，： | 1 |
| 10 | Risk factors and outcome of transfusion-related acute lung injury in the critically ill: A nested case–control study显示文摘 | Alexander P. J. Vlaar Jan M. Binnekade David Prins Danielle van Stein Jorrit J. Hofstra Marcus J. Schultz Nicole P. Juffermans | 2010 | Critical Care Medicine2010，，3： | 1 |
| 11 | Mediation of transforming growth factor β1 -stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring 显示文摘 | Daniels J T Schultz G S Blalock T D | 2003 | Am J Pathol2003，163，5： | 1 |
| 12 | Transforming growth factor beta in cardiovascular development and function显示文摘 | Mohamad Azhar Jo El J. Schultz Ingrid Grupp Gerald W. Dorn Pierre Meneton Daniel G.M. Molin Adriana C. Gittenberger-de Groot Thomas Doetschman | 2003 | Cytokine and Growth Factor Reviews2003，，5： | 1 |
| 13 | Mediation of transforming growth factor beta ( 1 ) stimulated matrix contraction by fibroblasts 显示文摘 | Schultz GS Blalock TD | 2003 | Am J pathol2003，163，5： | 1 |
| 14 | Resistance mechanism to cisplatin in NCI-H460 non-small cell lung cancer cell line:investigating apoptosis,autophagy,and cytogenetic damage显示文摘Aim:To investigate the effects of cisplatin on the human non-small cell lung carcinoma(NCI-H460)cell line regarding cytotoxicity,genotoxicity,and expression of genes associated with apoptosis(BIRC5)and autophagy(BECN1).Methods:Cell cultures were treated with cisplatin concentrations(0.16-33.3μmol/L)for 48 h.Mutagenicity and acute and chronic cytotoxicities were assessed using the MTT,clonogenic,and cytokinesis-block micronucleus assays.Gene expression of BIRC5 and BECN1 was evaluated by reverse transcription-polymerase chain reaction.Results:Cisplatin IC50(0.33μmol/L)increased micronucleus frequency 2.50 times.Cisplatin was also cytotoxic in the 0.6-33.3μmol/L range,with reduced expression of the BIRC5 gene,suggesting induction of apoptosis.Besides reducing the expression of the BIRC5 gene,33.3μmol/L cisplatin increased the expression of the BECN1 gene,suggesting that autophagy can be related to cisplatin resistance.Conclusion:Cisplatin inhibited NCI-H460 growth,and cisplatin IC50 induced genotoxic damage.When higher cisplatin concentrations are used,the expression of genes associated with apoptosis and autophagy was changed.This results points to a further investigation of the role of autophagy in cisplatin resistance. | Érica Ballestreri Daniel Simon Ana Paula de Souza Camila Schultz Grott Débora Dreher Nabinger Rafael Rodrigues Dihl Ivana Grivicich | 2018 | Cancer Drug Resistance2018，1，1： | 1 |
| 15 | Nonlinear tensile and shear behavior of macro fiber composite actuators显示文摘 | Inman Daniel Schultz M R | 2004 | Journal of Composite Materials2004，38，10： | 1 |
| 16 | Mediation of transforming growth factor-beta( 1 )-stimulated matrix contraction by fibro- blasts:a role for connective tissue growth factor in contractile scarring显示文摘 | Daniels JT Schultz GS Blalock TD | 2003 | Am J Patho12003，163，5： | 1 |
| 17 | Mediation of transforming growth factor-{beta}1 stimulated matrix contraction by fibroblasts:A Role for connective tissue growth factor in contractile scarring显示文摘 | Daniels JT Schultz GS Blalock TD Garrett Q Grotendorst GR Dean NM | 2003 | Am J Pathol2003，163，5： | 1 |
| 18 | Mediation of transforming growth factor-β1-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring显示文摘 | Daniels JT Schultz GS Blalock TD | 2003 | Am J Pathol2003，163，5： | 1 |
| 19 | Mediation of transforming growth factor-beta( 1 )-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring显示文摘 | Daniels J T Schultz G S Blalock T D | 2003 | Am J Pathol2003，163，5： | 1 |
| 20 | Mediation of transforming growth factor-betal stimulated matrix contraction by fibroblasts fibroblasts: a role for connective tissue growth factor in contractile scarring 显示文摘 | Daniels JT Schultz GS Blalock TD Garrett Q Grotendorst GR Dean NM | 2003 | Am J Pathol2003，163，5： | 1 |
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