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| 1 | Sleep disorders and chronic kidney disease显示文摘Sleep disorders have a profound and well-documented impact on overall health and quality of life in the general population. In patients with chronic disease, sleep disorders are more prevalent, with an additional morbidity and mortality burden. The complex and dynamic relationship between sleep disorders and chronic kidney disease(CKD) remain relatively little investigated. This article presents an overview of sleep disorders in patients with CKD, with emphasis on relevant pathophysiologic underpinnings and clinical presentations. Evidence-based interventions will be discussed, in the context of individual sleep disorders, namely sleep apnea, insomnia, restless leg syndrome and excessive daytime sleepiness. Limitations of the current knowledge as well as future research directions will be highlighted, with a final discussion of different conceptual frameworks of the relationship between sleep disorders and CKD. | Stephanie C Maung Ammar El Sara Cherylle Chapman Danielle Cohen Daniel Cukor | 2016 | World Journal of Nephrology2016，5，3： | 13 |
| 2 | Trans-arterial chemo-embolization is safe and effective for very elderly patients with hepatocellular carcinoma显示文摘AIM: To assess the safety and efficacy of trans-arterial chemo-embolization (TACE) in very elderly patients. METHODS: A prospective cohort study, from 2001 to 2010, compared clinical outcomes following TACE between patients ≥ 75 years old and younger patients (aged between 65 and 75 years and younger than 65 years) with hepatocellular carcinoma (HCC), diagnosed according to the European Association for the Study of the Liver and the American Association for the Study of Liver Diseases criteria. The decision that patients were not candidates for curative therapy was made by a multidisciplinary HCC team. Data collected included demographics, co-morbidities, liver disease etiology, liver disease severity and the number of procedures. The primary outcome was mortality; secondary outcomes included post-embolization syndrome (nausea, fever, abdominal right upper quadrant pain, increase in liver enzymes with no evidence of sepsis and with a clinical course limited to 3-4 d post procedure) and 30-d complications. Additionally, changes in liver enzyme measurements were assessed [alanine and aspartate aminotransferase (ALT and AST), gamma-glutamyl transpeptidase and alkaline phosphatase] in the week following TACE. Analysis employed both univariate and multivariate methods (Cox regression models). RESULTS: Of 102 patients who underwent TACE as sole treatment, 10 patients (9.8%) were > 80 years old at diagnosis; 13 (12.7%) were between 75 and 80 years, 45 (44.1%) were between 65 and 75 years and 34 (33.3%) were younger than 65 years. Survival analysis demonstrated similar survival patterns between the elderly patients and younger patients. Age was also not associated with the adverse event rate. Survival rates at 1, 2 and 3 years from diagnosis were 74%, 37% and 31% among patients < 65 years; 83%, 66% and 48% among patients aged 65 to 75 years; and 86%, 41% and 23% among patients ≥ 75 years. There were no differences between the age groups in the pre-procedural care, including preventive treatment for contrast nephropathy and prophylactic antibiotics. Multivariate survival analysis, controlling for disease stage at diagnosis with the Barcelona Clinic Liver Cancer score, number of TACE procedures, sex and alphafetoprotein level at the time of diagnosis, found no significant difference in the mortality hazard for elderly vs younger patients, and there were no differences in post-procedural complications. Serum creatinine levels did not change after 55% of the procedures, in all age groups. In 42% of all procedures, serum creatinine levels increased by no more than 25% above the baseline levels prior to TACE. Overall, there were 69 post-embolization events (23%). Hepatocellular enzymes often increased following TACE, with no association with prognosis. In 40% of the procedures, ALT and AST levels rose by at least 100%. The increases in hepatocellular enzymes occurred similarly in all age groups. CONCLUSION: TACE is safe and effective in very elderly patients with HCC, and is not associated with decreased survival or increased complication rates. | Matan J Cohen Allan I Bloom Orly Barak Alexander Klimov Tova Nesher Daniel Shouval Izhar Levi Oren Shibolet | 2013 | World Journal of Gastroenterology2013，19，16： | 13 |
| 3 | Accrual-based and real earnings management activities around seasoned equity offerings显示文摘 | Daniel A. Cohen Paul Zarowin | 2010 | Journal of Accounting and Economics2010，，1： | 10 |
| 4 | Prospective, randomized, endoscopic-blinded trial comparing precolonoscopy bowel cleansing methods显示文摘 | Stephen M. Cohen M.D. Steven D. Wexner M.D. Sander R. Binderow M.D. Juan J. Nogueras M.D. Norma Daniel R.N. Eli D. Ehrenpreis M.D. Jonathan Jensen M.D. Gregory F. Bonner M.D. William B. Ruderman M.D | 1994 | Diseases of the Colon & Rectum1994，，7： | 2 |
| 5 | Hysteroscopy May Be the Method of Choice for Management of Residual Trophoblastic Tissue显示文摘 | Shlomo B. Cohen Anath Kalter-Ferber Boaz S. Weisz Yaron Zalel Daniel S. Seidman Shlomo Mashiach Arie L. Lidor Mati Zolti Mordechai Goldenberg | 2001 | American Association of Gynecologic Laparoscopists2001，，2： | 2 |
| 6 | Combined Thermo-Chemotherapy for Recurrent Bladder Cancer After Bacillus Calmette-Guerin显示文摘 | Ofer Nativ J. Alfred Witjes Kees Hendricksen Michael Cohen Daniel Kedar Ami Sidi Renzo Colombo Ilan Leibovitch | 2009 | The Journal of Urology2009，，4： | 2 |
| 7 | Incremental Prognostic Value of Myocardial Perfusion Single Photon Emission Computed Tomography for the Prediction of Cardiac Death: Differential Stratification for Risk of Cardiac Death and Myocardial Infarction显示文摘 | Rory Hachamovitch Daniel S. Berman Leslee J. Shaw Hosen Kiat Ishac Cohen J. Arthur Cabico John Friedman George A. Diamond | 1998 | Circulation1998，，6： | 2 |
| 8 | The financial reporting environment: Review of the recent literature显示文摘 | Anne Beyer Daniel A. Cohen Thomas Z. Lys Beverly R. Walther | 2010 | Journal of Accounting and Economics2010，，2： | 2 |
| 9 | Laparoscopic detorsion allows sparing of the twisted ischemic adnexa显示文摘 | Shlomo B. Cohen Gabriel Oelsner Daniel S. Seidman Dahlia Admon Shlomo Mashiach Mordechai Goldenberg | 1999 | American Association of Gynecologic Laparoscopists1999，，2： | 1 |
| 10 | Absorptive Capacity:A New Perspective on Learning and Innovation显示文摘 | Wesley M Cohen Daniel A Levinthal | 1990 | Administrative Science Quarterly1990，35，： | 1 |
| 11 | Molecular characterisation of two divergent variants of grapevine leafroll-associated virus 3 in New Zealand显示文摘 | Kar Mun Chooi Daniel Cohen Michael N. Pearson | 2013 | Archives of Virology2013，，7： | 1 |
| 12 | The selective estrogen receptor modulator, raloxifene: a segment Ⅱ/Ⅲ delivery study in rats 显示文摘 | Buelke - Sam Judy Cohen Ilene R Wierda Daniel | 1998 | Reproductive Toxicology1998，12，3： | 1 |
| 13 | The Perception of Gastroenterology Fellows towards the Relationship between Hand Size and Endoscopic Training显示文摘 | Daniel L. Cohen Jahnavi R. Naik Leonardo J. Tamariz Ryan D. Madanick | 2008 | Digestive Diseases and Sciences2008，，7： | 1 |
| 14 | Absorptive Ca- pacity: A New Perspective on Learning and Innovation 显示文摘 | WESLEY M COHEN DANIEL A LEVINTHAL | 1990 | Admin- istrative Science Quarterly1990，35，1： | 1 |
| 15 | Absorptive capacity : Anew perspective on learning and innovation显示文摘 | Cohen Wesley M Levinthal Daniel A | 1990 | AdministrativeScience Quarterly1990，35，1： | 1 |
| 16 | War- ranty Reserve : Contingent Liability, Strategic Signal, or Earn- ings Management Tool? 显示文摘 | Daniel Cohen Masako Darrough Tzachi Zach | 2011 | The Accounting Review2011，，86： | 1 |
| 17 | Absorptive capacity:a new perspective on learning and innovation显示文摘 | COHEN WESLEY LEVINTHAL DANIEL A | 1990 | Administrative Science Quarterly1990，35，1： | 1 |
| 18 | Statistical Analysis of MPEG-2 Coded VBR Movie So urce显示文摘 | 3,Heyman Daniel Cohen David M | 1996 | Multimedia Communication and Video Coding1996，，： | 1 |
| 19 | Crystal structure of the hCASK PDZ domain reveals the structural basis of class Ⅱ PDZ domain target recognition显示文摘 | Daniels D L Cohen A R | 1998 | Nat Struct Biol1998，5，4： | 1 |
| 20 | A novel heterocyclic atom exchange reaction with Lawesson' s reagent: a one-pot synthesis of dithiomahol 显示文摘 | Daniel Brayton Faith E Jacobsen Seth M Cohen | 2006 | Chem Commun2006，，： | 1 |
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