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| 1 | XRCC1 and DNA polymerase β in cellular protection against cytotoxic DNA single-strand breaks显示文摘 | Julie K Horton Mary Watson Donna F Stefanick Daniel T Shaughnessy Jack A Taylor Samuel H Wilson | 2008 | Cell Research2008，18，1： | 17 |
| 2 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 3 | Carcinoma in situ in a 7 mm gallbladder polyp: Time to change current practice?显示文摘Detection of polypoid lesions of the gallbladder is increasing in conjunction with better imaging modalities. Accepted management of these lesions depends on their size and symptomatology. Polyps that are symptomatic and/or greater than 10 mm are generally removed, while smaller, asymptomatic polyps simply monitored. Here, a case of carcinoma-in-situ is presented in a 7 mm gallbladder polyp. A 25-year-old woman, who had undergone a routine cholecystectomy, was found to have an incidental 7 mm polyp containing carcinoma in situ. She had few to no risk factors to alert to her condition. There are few reported cases of cancer transformation in gallbladder polyps smaller than 10 mm reported in the literature. The overwhelming consensus, barring significant risk factors for cancer being present, is that such lesions should be monitored until they become symptomatic or develop signs suspicious for malignancy. In our patient's case this could have led to the possibility of missing a neoplastic lesion, which could then have gone on to develop invasive cancer. As gallbladder carcinoma is an aggressive cancer, this may have led to a tragic outcome. | David Kasle Amir A Rahnemai-Azar Shahida Bibi Vinaya Gaduputi Brian F Gilchrist Daniel T Farkas | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，9： | 8 |
| 4 | Laparoscopic vs open partial colectomy in elderly patients:Insights from the American College of Surgeons- National Surgical Quality Improvement Program database显示文摘AIM: To compare the outcomes between the laparoscopic and open approaches for partial colectomy in elderly patients aged 65 years and over using the American College of Surgeons- National Surgical Quality Improvement Program(ACS NSQIP) database. METHODS: The ACS NSQIP database for the years 2005-2011 was queried for all patients 65 years and above who underwent partial colectomy. 1:1 propensity score matching using the nearest- neighbor method was performed to ensure both groups had similar preoperative comorbidities. Outcomes including postoperative complications, length of stay and mortality were compared between the laparoscopic and open groups. χ2 and Fisher's exact test were used for discrete variables and Student's t-test for continuous variables. P < 0.05 was considered significant and odds ratios with 95%CI were reported when applicable. RESULTS: The total number of patients in the ACS NSQIP database of the years 2005-2011 was 1777035. We identified 27604 elderly patients who underwent partial colectomy with complete data sets. 12009(43%) of the cases were done laparoscopically and15595(57%) were done with open. After propensity score matching, there were 11008 patients each in the laparoscopic(LC) and open colectomy(OC) cohorts. The laparoscopic approach had lower post-operative complications(LC 15.2%, OC 23.8%, P < 0.001), shorter length of stay(LC 6.61 d, OC 9.62 d, P < 0.001) and lower mortality(LC 1.6%, OC 2.9%, P < 0.001). CONCLUSION: Even after propensity score matching, elderly patients in the ACS NSQIP database having a laparoscopic partial colectomy had better outcomes than those having open colectomies. In the absence of specific contraindications, elderly patients requiring a partial colectomy should be offered the laparoscopic approach. | Umashankkar Kannan Vemuru Sunil K Reddy Amar N Mukerji Vellore S Parithivel Ajay K Shah Brian F Gilchrist Daniel T Farkas | 2015 | World Journal of Gastroenterology2015，21，45： | 3 |
| 5 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 6 | Depletion patterns of radioactivity and tissue residues in beef cattle after the withdrawal of oral 14C-Diethylstilbestrol 显示文摘 | Rumsey T S Oltjen R R Daniels F L | 1975 | J Anim Sci1975，40，3： | 1 |
| 7 | Lack of RH C/E expression in the rhesus D-phenotype is the result of a gene deletion显示文摘 | Blunt T Steers F Daniels G | 1994 | Ann Hum Genet1994，，： | 1 |
| 8 | Use of Fenton for the treatment of leachate from composting of different wastes显示文摘 | Daniel T Xavier F Antoni S | 2006 | Journal of Hazardous Materials2006，136，12： | 1 |
| 9 | Anterior and posterior fusion for children with tuberculosis of the spine显示文摘 | Altman Gregory T Altnab Daniel T Frankovitch Karl F | 1996 | Clin Orthop Relat Res1996，，325： | 1 |
| 10 | Activated carbons from lignin:kinetic modeling of the pyrolysis of kraft lignin activated with phosphoric acid显示文摘 | Daniel M Vanessa T F Vanessa F | 2005 | Chemical Engineering Journal2005，106，： | 1 |
| 11 | Novel macrolide from wild strains of the phytopathogen fungus Colletotrichum acutatum 显示文摘 | GABRIELA M DANIEL J T MARIENCA F R | 2009 | Nat Prod Colnmun2009，4，3： | 1 |
| 12 | A processing, characterization and marine biodegradation study of melt-extruded polyhydroxyalkanoate (pha) films显示文摘 | Christopher T Megan C Danielle F | 2008 | Journal of Polymers and Environment2008，16，1： | 1 |
| 13 | Application of an Optimal Look-Up Table to Sensor Data Processing显示文摘 | Alessandra F Daniele M Andrea T | 1999 | IEEE Transactions on Instrumentation and Measurement1999，48，4： | 1 |
| 14 | Mechanism of AP - 1 - mediated gene expression by select organochlorines through the p38 MAPK pathway显示文摘 | Daniel E F Yan T B Beckman S | 2004 | Carcinogencsis2004，25，2： | 1 |
| 15 | The impact of compliance with 6 hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study显示文摘 | Gao F Melody T Daniels D F | 2005 | Crit Care2005，9，6： | 1 |
| 16 | Toxicity studies of 1,3- dichlorobenzene in Sprague-Dawley rats显示文摘 | McCauley P T Robinson M Daniel F B | 1995 | Drug and Chemical Toxicology1995，18，23： | 1 |
| 17 | Characterization of a new vacuolar membrane aquaporin sensitive to mercury at a unique site显示文摘 | DANIELS M J CHAUMONT F MIRKOV T E | 1996 | Plant Cel1996，8，4： | 1 |
| 18 | Investigation of the factor affecting the performance of a rotating heat pipe 显示文摘 | Daniels T AI-Jumaily F | 1975 | International Journal of Heat and Mass Transfer1975，18，7： | 1 |
| 19 | Radial artery bypass graftshave an increased occurrence of angiographically severe stenosisand occlusion compared with left internal mammary arteries and sa-phenous vein grafts显示文摘 | Umesh N K Daniel T F Gosta P | 2004 | Circulation2004，109，17： | 1 |
| 20 | Secular trends of chickenpox among military population in Israel in relation to introduction of varicella zoster vaccine 1979- 2010 显示文摘 | Daniel M Hagai L Anat T F | 2013 | Hum Vaccin Immunother2013，9，6： | 1 |
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