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您的检索式：作者名="Daniel L.E.Waters"
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| 1 | Association Mapping and Marker Development of Genes forStarch Lysophospholipid Synthesis in Rice显示文摘Phospholipids are a major kind of lipids in rice grains and have fundamental nutritional and functional benefits to the plant. Their lyso forms(lysophospholipids, LPLs) often form inclusion complexes with amylose or independently influence the physicochemical and functional properties of rice starch. However, the genetic basis for LPL synthesis in rice endosperm is largely unknown. Here, we performed a preliminary association test of 13 LPL compositions among 20 rice accessions, and identified 22 putative main-effect quantitative trait loci responsible for all LPLs except for LPC14:0 and LPE14:0. Five derived cleaved amplified polymorphic sequences and one insertion/deletion marker for three LPL-synthesis-related candidate genes were developed. Association analysis revealed two markers significantly associated with starch LPL traits. These results provide an insight into the genetic basis of phospholipid biosynthesis in rice and may contribute to the rice quality breeding programs using functional markers. | TONG Chuan LIU Lei Daniel L.E.WATERS BAO Jin-song | 2016 | Rice science2016，23，6： | 3 |
| 2 | The effect of selected hemp seed protein hydrolysates in modulating vascular function显示文摘Reduced bioavailability of nitric oxide along with an increase in inflammatory cytokines,reactive oxygen species,cell adhesion molecules,and platelet hyperactivity are underlying causes of endothelial dysfunction.Bioactive peptides derived from various plants have been shown to attenuate biomarkers of endothelial dysfunction.The objective of this study was to determine the effects of hemp seed protein hydrolysates(HSPH)in modulating biomarkers of endothelial dysfunction using an in vitro cell culture model and an ex vivo platelet activity assay.HUVEC cells were treated with HSPH from commercial variant X and ECO-commercial variant Y,followed by hydrogen peroxide to simulate oxidative stress and inflammation.Biomarkers of endothelial dysfunction were then measured to determine the protective properties of HSPH.Blood samples collected from healthy volunteers were used to determine the effect of the HSPH on ADP and hydrogen peroxide-induced platelet activity,using flow cytometry.The HSPH reduced the production of reactive oxygen species,inflammatory cytokines IL-8,IL-12p70 and IL-1β,and adhesion molecule vascular cell adhesion molecule 1.Additionally,treatment with HSPH also reduced platelet activation marker CD62P ex vivo.The results obtained from this study suggest HSPH alleviates biomarkers of endothelial dysfunction by reducing oxidative stress,inflammation and platelet activation. | Raiyan Mahbub Esther Callcott Shiwangni Rao Omid Ansari Daniel L.E.Waters Christopher L.Blanchard Abishek B.Santhakumar | 2022 | Food Bioscience2022，45，1： | 1 |
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