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| 1 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009,,9: | 2 |
| 2 | 25 Gbps low-voltage hetero-structured silicongermanium waveguide pin photodetectors for monolithic on-chip nanophotonic architectures显示文摘Near-infrared germanium(Ge) photodetectors monolithically integrated on top of silicon-on-insulator substrates are universally regarded as key enablers towards chip-scale nanophotonics, with applications ranging from sensing and health monitoring to object recognition and optical communications. In this work, we report on the highdata-rate performance pin waveguide photodetectors made of a lateral hetero-structured silicon-Ge-silicon(Si-Ge-Si) junction operating under low reverse bias at 1.55 μm. The pin photodetector integration scheme considerably eases device manufacturing and is fully compatible with complementary metal-oxide-semiconductor technology. In particular, the hetero-structured Si-Ge-Si photodetectors show efficiency-bandwidth products of^9 GHz at-1 V and ~30 GHz at-3 V, with a leakage dark current as low as ~150 nA, allowing superior signal detection of high-speed data traffic. A bit-error rate of 10-9 is achieved for conventional 10 Gbps, 20 Gbps, and25 Gbps data rates, yielding optical power sensitivities of-13.85 dBm,-12.70 dBm, and-11.25 dBm, respectively. This demonstration opens up new horizons towards cost-effective Ge pin waveguide photodetectors that combine fast device operation at low voltages with standard semiconductor fabrication processes, as desired for reliable on-chip architectures in next-generation nanophotonics integrated circuits. | DANIEL BENEDIKOVIC LéOPOLD VIROT GUY AUBIN FARAH AMAR BERTRAND SZELAG BAYRAM KARAKUS JEAN-MICHEL HARTMANN CARLOS ALONSO-RAMOS XAVIER LE ROUX PAUL CROZAT ERIC CASSAN DELPHINE MARRIS-MORINI CHARLES BAUDOT FRéDéRIC BOEUF JEAN-MARC FéDéLI CHRISTOPHE KOPP LAURENT VIVIEN | 2019 | Photonics Research2019,7,4: | 2 |
| 3 | Chemically grafted polymeric filters for chemical sensors: hyperbranched poly ( acrylic acid) films incorporatingh - cyclodextrin receptors and amine - functionalized filter layers 显示文摘 | Daniel L Dermody Robert F Peez D E | 1999 | Langmuir1999,15,3: | 1 |
| 4 | MRI of the cavernous sins:value of spin echo and gradient recalled echo images显示文摘 | DANIELS D L CZERVIONKE L F BONNEVILLE J F | 1998 | AJR1998,151,: | 1 |
| 5 | The impact of compliance with 6 hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study显示文摘 | Gao F Melody T Daniels D F | 2005 | Crit Care2005,9,6: | 1 |
| 6 | Robust H∞ filtering for stochastic time-delay systems with missing measurements 显示文摘 | WANG Z D YANG F W DANIEL W C H | 2006 | IEEE Transactions on Signal Processing2006,54,7: | 1 |
| 7 | Effect of relative impeller-to-volute position on hydraulic efficiency and static radial force distribution in a circular volute cen- trifugal pump 显示文摘 | Daniel O B Lutz K Ronald D F | 2000 | Transactions of the ASME2000,122,3: | 1 |
| 8 | c-erbB-2 in breast cancer:development of a clinically useful marker显示文摘 | Thor Ann D | 2002 | Semin Oncol2002,29,3: | 1 |
| 9 | Magnetic resonance coupling as a potential means for wireless power transfer to multiple small receivers显示文摘 | BENJAMIN L C JAMES F H DANIEL D S | 2009 | IEEE transactions on power electronics2009,24,7: | 1 |
| 10 | Introduction to subsurface radar显示文摘 | DANIELS D J GUNTON D J SCOTT H F | 1988 | IEE Proceedings F Radar and Signal Processing1988,135,4: | 1 |
| 11 | Modelling global risk factors affecting construction cost performance显示文摘 | DANIEL B PRICE A D F | 2003 | Intern J Proj Manag2003,21,4: | 1 |
| 12 | Sex-stratifiedsocio-economie gradients in physical inactivity, obesity, and dia- betes:Evidence of short-term changes in Argentina 显示文摘 | BRUNO L FERNANDO D M DANIEL F | 2013 | lnt J Public Health2013,58,2: | 1 |
| 13 | Introduction to Subsurface Radar显示文摘 | Daniels D J Gunton D J Scott H F | 1988 | IEE Proceedings1988,135,4: | 1 |
| 14 | Linear, Random Representations of Chaos显示文摘 | Daniel F D Douglas B W | 2007 | IEEE Transactions on Signal Processing2007,55,4: | 1 |
| 15 | Xenon purity analysis for exo-200 via mass spectrometry 显示文摘 | Dobi A Hall C Slutsky S Yen Y R Aharmin B Auger M Barbeau P S Benitez-Medina C Breidenbach M Cleveland B Conley R Cook J Cook S Counts I Craddock W Daniels T Davis C G Davis J Devoe R Dixit M Dolinski M J Donato K Fairbank Jr W Farine J Fierlinger P Franco D Giroux G Gornea R Graham K Gratta G Green C Hagemann C Hall K Hallman D Hargrove C Herrin S Hughes M Hodgson J Juget F Karelin A Kaufman L J Kuchenkov A Kumar K Leonard D S Lutter G Mackay D Maclellan R Marino M Mong B Montero Diez M Morgan P MUller A R Neilson R Odian A Oullivan K Piepke A Pocar A Prescott C Y Pushkin K Rivas A Rollin E Rowson P C Sabourov A Sinclair D Skarpaas K Stekhanov V Strickland V Swift M Twelker K Vuilleumier J L Vuilleumier J M Weber M Wichoski U Wodin J Wright J D Yang L | 2012 | Nuclear Instruments and Methods in Physics Research Section A: Accelerators Spectrometers Detectors and Associated Equipment2012,675,: | 1 |
| 16 | Design & opera-tion of a selective sweetening plant using MDEA 显示文摘 | Mackenzie D H Prambil F C Daniels C A | 1987 | Energy Pro-gress1987,7,1: | 1 |
| 17 | Molecular characterization of the first Australian isolate of Japanese encephalitis virus, the FU strain 显示文摘 | Williams D T Wang L F Daniels P W | 2000 | J GenVirol2000,,: | 1 |
| 18 | The Multifunctionality of Agriculture and Contractual Policies,a Comparative Analysis of France and the Netherlands显示文摘 | Daniel F J Perraud D | 2009 | Journal of Environmental Management2009,,: | 1 |
| 19 | Liver failure after an uncovered TIPS procedure associated with hepatic infarction显示文摘Transjugular intrahepatic portosystemic shunt (TIPS) is a safe and effective procedure for the treatment of complications of liver cirrhosis, such as refractory ascites, hepatic hydrothorax and refractory variceal bleeding. The aim of this paper is to describe a rare case of liver failure after a TIPS procedure. A 38-year-old diabetic male with Child-Pugh C liver cirrhosis due to chronic hepatitis C infection who had developed refractory ascites was scheduled for a TIPS procedure. Within 24 h following TIPS placement, the patient developed distributive shock, jaundice, persistentgrade 3 hepatic encephalopathy, severe coagulopathy andacute renal failure. He was treated with lactulose enemas, broad-spectrum antibiotics and blood-derived products. Laboratory data revealed a 100-fold increase in aminotransferases and a non-enhanced computed tomography showed an irregular hypodense area in the right posterior segment of the liver. Despite being initially being in a stable condition, the patient developed progressive liver failure and died 2 mo later. Hepatic infarction is an uncommon phenomenon after a TIPS procedure; however, it can greatly complicate the course of a disease in a patient with an already compromised liver function. | Eric López-Méndez Daniel Zamora-Valdés Mariana Díaz-Zamudio Oscar F Fernández-Díaz Lourdes ávila | 2010 | World Journal of Hepatology2010,2,4: | 1 |
| 20 | BAI 3, CDX 2 and VIL 1: a panel of three antibodies to distinguish small cell from large cell neuroendocrine lung carcinomas显示文摘 | Muhammad F Bari Helen Brown Andrew G Nicholson Keith M Kerr John R Gosney William A Wallace Irshad Soomro Salli Muller Danielle Peat Jonathan D Moore Lesley A Ward Maxim B Freidin Eric Lim Manu Vatish David R J Snead | 2014 | Histopathology2014,,: | 1 |