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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Ex vivo evaluation of a new neonatal/infant oxygenator:comparison of the Terumo CAPIOX Baby RX with Dideco Lilliput 1 and Polystan Safe Micro in the piglet model显示文摘 | Dubois J Jamaer L Mees U | 2004 | Perfusion2004，19，5： | 1 |
| 3 | Study of new catalysts based on vanadium oxide supported on mesoporous silica for the partial oxidation of methane to formaldehyde:Catalytic properties and reaction mechanism显示文摘 | NGUYEN L D LORIDANT S LAUNAY H PIGAMO A DUBOIS J L MILLET J M | | 0，，01： | 1 |
| 4 | Conversion of CO2 to dimethyl ether and methanol over hybrid catalysts 显示文摘 | Dubois J L Sayama K Arakawa H | 1992 | Chem Lett1992，，7： | 1 |
| 5 | Nature and nurture in brain development and neurological disorders显示文摘 | Dehaene-Lambertz G Hertz-Pannier L Dubois J | 2006 | Trends in Neurosciences2006，29，7： | 1 |
| 6 | Cyclooxygenase in biology and disease 显示文摘 | Dubois RN Abramson SB Crofford L | 1998 | FASEB J1998，12，12： | 1 |
| 7 | From Rumors to Facts, and Facts to Rumors: The Role of Certainty Decay in Consumer Communications 显示文摘 | Dubois D Derek D R Zakary L T | 2011 | Journal of Marketing Research2011，48，6： | 1 |
| 8 | Traumatic ulceration of the tongue in an infant显示文摘 | Dubois L Keuning KH Lindeboom JA | 2010 | Ned Tijdschr Tandheelkd2010，117，5： | 1 |
| 9 | New antibacterial peptide derived from bovine hemo- globin 显示文摘 | DAOUD R DUBOIS V BORS-DODITA L | 2005 | Peptides2005，26，5： | 1 |
| 10 | Interdependence in supply chains and projects in construction 显示文摘 | Bankvall L Bygballe L E Dubois A | 2010 | Supply Chain Management : An International Journal2010，15，5： | 1 |
| 11 | Mo2V-Te- (Nb)-O mixed metal oxides prepared by hydrothermal synthesis for catalytic selective oxidations of propane and propene to acrylic acid 显示文摘 | VITRY D MORIKAWA Y DUBOIS J L | 2003 | Applied Catalysis2003，251，2： | 1 |
| 12 | Repeated cycles of Clus- tridium-directed enzyme prodrug therapy result in sustained antitu- mour effects in vivo显示文摘 | Theys J Pennington O Dubois L | 2006 | Br J Cancer2006，95，9： | 1 |
| 13 | Excessive bleeding in the floor of the mouth after endosseus implant placement:a report of two cases显示文摘 | Dubois L de Lange J Baas E | 2010 | Int J Oral Maxillofac Surg2010，39，4： | 1 |
| 14 | Lymphangiomas in chlidren:percutaneous selerotherapy with an alcoholic solution of zein显示文摘 | DUBOIS J GAREL L ABELA A | 1997 | Radiology1997，204，3： | 1 |
| 15 | Imaging and teerapeutic approach of hemangioand vascular malformations in the pediatric age group显示文摘 | Dubois J Garel L | 1999 | Pediatr Radiol1999，29，12： | 1 |
| 16 | Two cytosolic glutamine synthetase isoforms of maize are specifically involved in the control of grain production 显示文摘 | Martin A Lee J Kichey T Gerentes D Zivy M Tatout C Dubois F Balliau T Valot B Davanture M Laforgue T T Quillere I Coque M Gallais A Moro M B G Bethencourt L Habash D Z Lea P J Charcosset A Perez P Murigneux A Sakakibara H Edwards K J Hirel B | 2006 | The Plant Cell2006，18，11： | 1 |
| 17 | 查看详情显示文摘 | Piraux L Dubois S | | 0，，： | 1 |
| 18 | Armored RNA technology for production ofribonuclease-resistant viral RNA controls andstandards显示文摘 | Pasloske B L Walkerpeach C R Obermoeller R D Winkler M DuBois D B | 1998 | J Clin Microbiol1998，36，12： | 1 |
| 19 | Ablation of the organic matrix: fundamen-tal response of a photo-aged epoxy-glass fibered composite 显示文摘 | Monney L Dubois C | 2001 | Polymer Degradation and Suability2001，56，3： | 1 |
| 20 | Determinants of birthweight inequalities: Population-based study 显示文摘 | Dubois L Girard M | 2006 | Pediatr Int2006，48，5： | 1 |
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