3篇
您的检索式：作者名="DIMITROPOULOU DIMITRA"
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| 1 | Serum cytokine profile in patients with hepatitis B e antigen-negative chronic active hepatitis B and inactive hepatitis B virus carriers显示文摘An insufficient cellular immune response seems to be critical for the immunopathogenesis of chronic hepatitis B virus infection.We have previously demonstrated no differences of T-lymphocyte subsets in blood between inactive hepatitis B s antigen(HBsAg) carriers and patients with HBeAg-negative chronic active hepatitis B.This study investigated the peripheral blood cytokine profile in patients with HBeAg-negative chronic active hepatitis B infection(Group A,n = 21) and inactive HBsAg carriers(Group B,n = 13).Serum cytokines [interferon(IFN)-γ,tumor necrosis factor-α,interleukin(IL)-1b,IL-4,IL-12,IL-10,IL-2,IL-5,IL-8] were analyzed by using flow cytometry.Patients with chronic active disease presented with significantly decreased levels of IFN-γ and IL-10 compared to inac-tive carriers(P = 0.048 and P = 0.008,respectively).In HBeAg-negative chronic active hepatitis B patients,a significant negative correlation of IFN-γ levels with serum hepatitis B viral load was noted(P = 0.021).In conclusion,patients with HBeAg-negative chronic active hepatitis B and HBsAg inactive carriers display a different cytokine profile.Decreased Th1 response observed in patients with chronic active hepatitis B could be implicated in the persistence of virus replication and ongoing progression of liver disease. | Dimitra Dimitropoulou Marina Karakantza Georgios L Theodorou Lydia Leonidou Stelios F Assimakopoulos Athanasia Mouzaki Charalambos A Gogos | 2013 | World Journal of Gastrointestinal Pathophysiology2013，4，1： | 13 |
| 2 | Prevalence of liver steatosis in patients with chronic hepatitis B: a study of associated factors and of relationship with fibrosis显示文摘 | Konstantinos C. Thomopoulos Vassiliki Arvaniti Athanasios C. Tsamantas Dimitra Dimitropoulou Charalambos A. Gogos Dimitrios Siagris George J. Theocharis Chryssoula Labropoulou-Karatza | 2006 | European Journal of Gastroenterology & Hepatology2006，，3： | 1 |
| 3 | The determinants of the location of foreign direct investment in UK regions 显示文摘 | DIMITROPOULOU DIMITRA MCCANN PHILIP | 2013 | Applied Economics2013，，： | 1 |
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