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| 1 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019,6,3: | 15 |
| 2 | 柑桔黄龙病的鉴定和柯赫氏定理(英文)显示文摘黄龙(梢)病被认为是世界柑橘生产上的毁灭性病害已超过一个世纪,但该病害的病原学至今还没有清晰地建立起来。根据16S rRNA基因序列分析,一组被称为'Candidatus Liberibacter species'的难培养细菌被认为与黄龙病相关。然而,要确定'Ca.Liberibacter spp.'是黄龙病病原的柯赫氏定理并没有真正完成。令我们担忧的是,近年来有些文献频频指出'Ca.Liberibacter spp.'是黄龙病的病原,其实该细菌与柑橘寄主的直接病理反应还没有完全确定。我们建议,在黄龙病病原学清楚之前,文献报道在这方面需要有准确的阐述。 | Chen J Deng X Civerolo E L Lee R F Jones J B Zhou C Hartung J S Manjunath K L Brlansky R H | 2011 | 植物病理学报2011,41,2: | 10 |
| 3 | 2D structure with rectangular grids woven by coordination chains and pseudo-metal wires 显示文摘 | ZHANG H X KANG B S DENG L R | 2001 | Inorg Chem Commun2001,4,: | 1 |
| 4 | Practical protocols for certified electronic mail显示文摘 | Deng R H Gong L | 1996 | Journal of Network and Systems Management1996,4,3: | 1 |
| 5 | Inter-company comparison using modified TOPSIS with objective weights显示文摘 | H DENG C H YEH R J WILLIS | | 0,,04: | 1 |
| 6 | Finite-time H∞ con- trol for time-delayed stochastic systems with Markovian switching 显示文摘 | Gao W H Deng F Q Zhang R Q | 2014 | Abstract and Applied Analysis2014,2014,: | 1 |
| 7 | Crystal Growth and Scintillation Properties of CNGB∶Ce3+显示文摘 | Yang P Zhou X W Deng H R | 2013 | IEEE Transactions on Nuclear Science2013,60,2: | 1 |
| 8 | Link test-A statistical method for finding prostate cancer biomarkers 显示文摘 | Deng X Geng H Bastola D R | 2006 | Comput Biol Chem2006,30,9: | 1 |
| 9 | Synthesis of CuAlO2 Ceramics Using Sol-gel显示文摘 | Deng Z H Zhu X B Tao R H | 2007 | Materials Letters2007,61,: | 1 |
| 10 | Chemical-looping combustion of methane with CaSO4 oxygen carder in a fixed bed reactor 显示文摘 | SONG Q XIAO R DENG Z ZHANG H SHEN L XIAO J ZHANG M | 2008 | Energy Convers Manage2008,49,11: | 1 |
| 11 | Bacterial community structure and diversity in a century - old manure - treated agroecosystem 显示文摘 | Sun H Y Deng S P Raun W R | 2004 | Ap- plied and Environmental Microbiology2004,70,10: | 1 |
| 12 | TLR3signaling in macrophages is indispensable for the protective immunity of invariant natural killer T cells against enterovirus 71infection显示文摘 | Zhu K Yang J Luo K Yang C Zhang N Xu R Chen J Jin M Xu B Guo N Wang J Chen Z Cui Y Zhao H Wang Y Deng C Bai L Ge B Qin C F Shen H Yang C F Leng Q | 2015 | PLoS Pathog2015,11,10: | 1 |
| 13 | Mortgage terminations heterogeneity and the exercise of mortgage options显示文摘 | Deng Y H Quiley J M Order R V | 2000 | Econometrica2000,68,2: | 1 |
| 14 | Identification of a major co-receptor for primary isolates of HIV-1 显示文摘 | Deng H Liu R Elhneier W | 1996 | Nature1996,381,6584: | 1 |
| 15 | Multiple functional groups of varying ratios in metal-organic frameworks显示文摘 | Deng H Doonan C J Furukawa H Ferreira R B Towne J Knobler C B Wang B Yaghi O M | | 0,,: | 1 |
| 16 | 查看详情显示文摘 | Yan L W Duan X R Ding X T Dong J Q Yang Q W Liu Y Zou X L Liu D Q Xuan W M Chen L Y Rao J Song X M Huang Y Mao W C Wang Q M Li Q Cao Z Li B Cao J Y Lei G J Zhang J H Li X D Chen W Cheng J Cui C H Cui Z Y Deng Z C Dong Y B Feng B B Gao Q D Han X Y Hong W Y | | 0,,: | 1 |
| 17 | Application of an antibacterial dressing spray in the prevention of post-operative infection in oral cancer patients:a phase 1 clinical trial显示文摘 | ZENG Y Z DENG R Z YEUNG H S | 2008 | Afr J Biotechnol2008,7,21: | 1 |
| 18 | Inter-company comparison using modified TOPSIS with objective weights显示文摘 | DENG H YEH C WILLIS R | 2000 | Comput- ers and Operations Research2000,27,10: | 1 |
| 19 | HMM-based strategies for enhancement of speech signals embedded in non- stationary noise 显示文摘 | Sameti H Sheikhzadeh H Deng L Brennan R L | 1998 | IEEE Transactions on Speech and Audio Processing1998,6,5: | 1 |
| 20 | Synthesis of Cu Al O2Ceramics Using Sol-gel显示文摘 | Deng Z H Zhu X B Tao R H | 2007 | Materials Letters2007,61,: | 1 |