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| 1 | Male infertility: lifestyle factors and holistic, complementary, and alternative therapies显示文摘当我们可能与男不孕的一条对症疗法的途径是舒适的时,我们为生活方式修正和被许多我们的病人使用的整体、互补、其他的治疗的知识也负责。这份报纸提供为几这些治疗把事实与小说分开的基于证据的评论。有足够的文学由饮食和锻练支持重量减小,吸停止,和白酒中等。在小使随机化的控制试用(RCT ) 上在男富饶上表明了积极效果的补充包括 aescin,辅酶 Q 10, 谷胱甘肽,朝鲜红人参, L 肉毒碱, nigella sativa, omega-3,硒,锌的联合并且叶酸,并且 Menevit 抗氧化剂。对维生素 C,维生素 E,或藏花的使用没有支持。为中国草药的药的数据,针灸,头脑身体实践,阴囊的冷却,并且基于信心的愈合稀少或不确定。 | David F Yao Jesse N Mills | 2016 | Asian Journal of Andrology2016，18，3： | 11 |
| 2 | Dietary and metabolomic determinants of relapse in ulcerative colitis patients: A pilot prospective cohort study显示文摘AIM To identify demographic, clinical, metabolomic, and lifestyle related predictors of relapse in adult ulcerative colitis(UC) patients.METHODS In this prospective pilot study, UC patients in clinical remission were recruited and followed-up at 12 mo to assess a clinical relapse, or not. At baseline information on demographic and clinical parameters was collected. Serum and urine samples were collected for analysis of metabolomic assays using a combined direct infusion/liquid chromatography tandem mass spectrometry and nuclear magnetic resolution spectroscopy. Stool samples were also collected to measure fecal calprotectin(FCP). Dietary assessment was performed using a validated self-administered food frequency questionnaire. RESULTS Twenty patients were included(mean age: 42.7 ± 14.8 years, females: 55%). Seven patients(35%) experienced a clinical relapse during the follow-up period. While 6 patients(66.7%) with normal body weight developed a clinical relapse, 1 UC patient(9.1%) who was overweight/obese relapsed during the follow-up(P = 0.02). At baseline, poultry intake was significantly higher in patients who were still in remission during follow-up(0.9 oz vs 0.2 oz, P = 0.002). Five patients(71.4%) with FCP > 150 μg/g and 2 patients(15.4%) with normal FCP(≤ 150 μg/g) at baseline relapsed during the follow-up(P = 0.02). Interestingly, baseline urinary and serum metabolomic profiling of UC patients with or without clinical relapse within 12 mo showed a significant difference. The most important metabolites that were responsible for this discrimination were trans-aconitate, cystine and acetamide in urine, and 3-hydroxybutyrate, acetoacetate and acetone in serum. CONCLUSION A combination of baseline dietary intake, fecal calprotectin, and metabolomic factors are associated with risk of UC clinical relapse within 12 mo. | Ammar Hassanzadeh Keshtel iFloris F van den Brand Karen L Madsen Rupasri Mandal Rosica ValchevaKaren I Kroeker Beomsoo Han Rhonda C Bell Janis Cole Thomas Hoevers David S Wishart Richard N Fedorak Levinus A Dieleman | 2017 | World Journal of Gastroenterology2017，23，21： | 9 |
| 3 | High-pressure methane and carbon dioxide adsorption on dry and moisture-equilibrated Pennsylvanian coals显示文摘 | B.M Krooss F van Bergen Y Gensterblum N Siemons H.J.M Pagnier P David | 2002 | International Journal of Coal Geology2002，，2： | 3 |
| 4 | The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase显示文摘 | Thomas F Franke Sung-Il Yang Tung O Chan Ketaki Datta Andrius Kazlauskas Deborah K Morrison David R Kaplan Philip N Tsichlis | 1995 | Cell1995，，5： | 2 |
| 5 | Antiestrogenic properties of raloxifene显示文摘 | Michael W D David E F Julie A N | 1995 | Parmacology1995，50，： | 1 |
| 6 | LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator显示文摘 | Davide N Mauri Reinhard Ebner Rebecca I Montgomery Kristine D Kochel Timothy C Cheung Guo-Liang Yu Steve Ruben Marianne Murphy Roselyn J Eisenberg Gary H Cohen Patricia G Spear Carl F Ware | 1998 | Immunity1998，，： | 1 |
| 7 | High-pressure methane and carbon dioxide adsorption on dry and moisture-equilibrated Pennsylvanian coals显示文摘 | Krooss B M van Bergen F Gensterblum Y Siemons N Pagnier H J M David P | 2002 | Int J Coal Geol2002，51，2： | 1 |
| 8 | Notes on colons distribution in plant populations显示文摘 | DAVID F N MOORE P G | 1954 | Annals Botany1954，18，： | 1 |
| 9 | Current tissue engineering strategies in anterior cruciate ligament reconstruction 显示文摘 | LEONG N L FRANK F A DAVID R M | 2014 | Journal of Biomedical Materials Research : Part A2014，102，5： | 1 |
| 10 | Pure lead and the tin effect in deep-cycling lead-acid battery applications 显示文摘 | Robert F N David M W | 1991 | Journal of Power Sources1991，33，1： | 1 |
| 11 | Detecting novel associations in large datasets显示文摘 | DAVID N R YAKIR A R HILARY K F | 2011 | Science2011，334，6062： | 1 |
| 12 | Seasonal changes in the respiratory electron transport system (ETS) and respiration of the zebra mussel,Dreissena polymorpha in Saginaw Bay?Lake Huron显示文摘 | DAVID L F THOMAS F N THOMAS H J | 2001 | Hydrobiologia2001，448，： | 1 |
| 13 | Antiepileptic drugs-best practice guidelines for therapeutic drug monitoring: A position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies 显示文摘 | Philip N David J Blaise F | 2008 | Epilepsia2008，49，7： | 1 |
| 14 | Optical fibre sensors for remote monitoring of tunnel displacements-Prototype tests in the laboratory显示文摘 | METJE Nicole CHAPMAN DAVID N ROGERS C D F | 2006 | Tunnelling and Underground Space Technology2006，21，： | 1 |
| 15 | Long tern: follow up of chiari-related syringomyelia in adults: analysis of 157 surgically treated eases显示文摘 | Aghakhani N Parker F David P etal | 2009 | Neurosurgery2009，64，2： | 1 |
| 16 | Notes on contagious distribution in plant population 显示文摘 | David F N Moore P G | 1954 | Anrials of Botany1954，18，： | 1 |
| 17 | Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomised, double-blind, placebo-controlled, dose-escalation trial显示文摘 | Edward J Gane Stuart K Roberts Catherine AM Stedman Peter W Angus Brett Ritchie Rob Elston David Ipe Peter N Morcos Linda Baher Isabel Najera Tom Chu Uri Lopatin M Michelle Berrey William Bradford Mark Laughlin Nancy S Shulman Patrick F Smith | 2010 | The Lancet2010，，9751： | 1 |
| 18 | Long-term follow- up of Chiari-related syringomyelia in adults: analysis of 157 surgically treated cases显示文摘 | Aghakhani N Parker F David P | 2009 | Neurosurgery2009，64，2： | 1 |
| 19 | Macro thyrotropin-IgG, complex causes factitious increase in thyroid-stimulating hormone screening tests in a neonate and mother(letter) 显示文摘 | David J H Michael N F Hall S K | 2006 | Clin Chem2006，52，10： | 1 |
| 20 | l,ong-term follow- up of Chiari-related syringomyelia in adults: analysis of 157 surgically treated cases显示文摘 | Aghakhani N P arker F David P etal | 2009 | Neuroosurgery2009，64，2： | 1 |
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