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| 1 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 2 | Pancreatic cancer显示文摘 | Theresa Pluth Yeo Ralph H Hruban Steven D Leach Robb E Wilentz Taylor A Sohn Scott E Kern Christine A Iacobuzio-Donahue Anirban Maitra Michael Goggins Marcia I Canto Ross A Abrams Daniel Laheru Elizabeth M Jaffee Manuel Hidalgo Charles J Yeo | 2002 | Current Problems in Cancer2002，，4： | 2 |
| 3 | Development of ferrite rolling textures in low and extra low-carbon steels显示文摘 | Toth L S Jonas I J Daniel D | 1990 | Metallurgical Transactions1990，21，4： | 1 |
| 4 | Effectiveness of vegetative filter strips in controlling losses of surface-applied poultry litters constituents 显示文摘 | CHAUBEY I EDWARDS D R DANIEL T C | 1995 | Tran ASAE1995，38，6： | 1 |
| 5 | Activity and safety of crizotinib in patients with ALK -positive non-small-cell lung cancer: updated results from a phase 1 study显示文摘 | D Ross Camidge Yung-Jue Bang Eunice L Kwak A John Iafrate Marileila Varella-Garcia Stephen B Fox Gregory J Riely Benjamin Solomon Sai-Hong I Ou Dong-Wan Kim Ravi Salgia Panagiotis Fidias Jeffrey A Engelman Leena Gandhi Pasi A J?nne Daniel B Costa Geoffrey | 2012 | Lancet Oncology2012，，10： | 1 |
| 6 | Conserva- tion of surfactant protein A: evidence for a single origin for vertebrate pulmonary surfactant显示文摘 | Sullivan L C Daniels C B Phillips I D | 1998 | Mol Evol1998，46，2： | 1 |
| 7 | Effect of fixed bed drying on the retention of phenolic compounds, anthocyanins and antioxidant activity of roselle (Hibiscus sabdariffa L) 显示文摘 | Daniel D L Huerta B E B Sosa I A | 2012 | Ind Crop Prod2012，40，： | 1 |
| 8 | ICAT inhibits β-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300using independent structural modules显示文摘 | Daniels D L Weis W I | 2002 | Mol Cell2002，10，： | 1 |
| 9 | Xenon purity analysis for exo-200 via mass spectrometry 显示文摘 | Dobi A Hall C Slutsky S Yen Y R Aharmin B Auger M Barbeau P S Benitez-Medina C Breidenbach M Cleveland B Conley R Cook J Cook S Counts I Craddock W Daniels T Davis C G Davis J Devoe R Dixit M Dolinski M J Donato K Fairbank Jr W Farine J Fierlinger P Franco D Giroux G Gornea R Graham K Gratta G Green C Hagemann C Hall K Hallman D Hargrove C Herrin S Hughes M Hodgson J Juget F Karelin A Kaufman L J Kuchenkov A Kumar K Leonard D S Lutter G Mackay D Maclellan R Marino M Mong B Montero Diez M Morgan P MUller A R Neilson R Odian A Oullivan K Piepke A Pocar A Prescott C Y Pushkin K Rivas A Rollin E Rowson P C Sabourov A Sinclair D Skarpaas K Stekhanov V Strickland V Swift M Twelker K Vuilleumier J L Vuilleumier J M Weber M Wichoski U Wodin J Wright J D Yang L | 2012 | Nuclear Instruments and Methods in Physics Research Section A: Accelerators Spectrometers Detectors and Associated Equipment2012，675，： | 1 |
| 10 | Phenotypic Plasticity of Adventitious Rooting in Arabidopsis Is Controlled by Complex Regulation of AUXIN RESPONSE FACTOR Transcripts and MicroRNA Abundance(W)显示文摘 | Gutierrez Laurent Bussell John D Pacurar Daniel I Schwambach Josèli Pacurar Monica Bellini Catherine | 2009 | Plant Cell2009，，10： | 1 |
| 11 | Ligand properties of aromatic azines : C-H activation, metal induced disproportion ation and catalytic C-C coupling reactions 显示文摘 | Joachim W Wolfgang I | 2004 | Journal of Organometallic Chemistry2004，689，： | 1 |
| 12 | Conversation of surfactant protein A:evidence for a single origin vertebrate pulmonary surfactant显示文摘 | Sullivan L C Daniels C B Phillips I D etal | 1998 | J Mol Evo11998，46，2： | 1 |
| 13 | 显示文摘 | Saiful I M Daniel J D Craig A J | 2005 | Chemistry of Materials2005，17，20： | 1 |
| 14 | Criteria for the diagnosis of acute leukemia of megakaryocyte lineage (m?) 显示文摘 | BENNETT J M CATOVSKY D DANIEL M I | 1985 | Ann Intern Med1985，103，： | 1 |
| 15 | Beta-catenin: molecular plasticity and drug design显示文摘 | DANIELS D L EKLOFSPINK K WEIS W I | 2001 | Trends Biochem Sci2001，26，11： | 1 |
| 16 | Complexed prostate-specific antigen as a staging tool: results based on a multicenter prospective evaluation of complexed prostate-specific antigen in cancer diagnosis显示文摘 | Samir S Taneja Elias I Hsu Carol D Cheli Paul Walden Georg Bartsch Wolfgang Horninger Richard J Babaian Herbert A Fritsche Stacy Childs Thomas A Stamey Lori J Sokoll Daniel W Chan Michael K Brawer Alan W Partin Herbert Lepor | 2002 | Urology2002，，4： | 1 |
| 17 | Activity and safety of crizotinib in patients with ALK -positive non-small-cell lung cancer: updated results from a phase 1 study显示文摘 | D Ross Camidge Yung-Jue Bang Eunice L Kwak A John Iafrate Marileila Varella-Garcia Stephen B Fox Gregory J Riely Benjamin Solomon Sai-Hong I Ou Dong-Wan Kim Ravi Salgia Panagiotis Fidias Jeffrey A Engelman Leena Gandhi Pasi A J?nne Daniel B Costa Geoffrey | 2012 | Lancet Oncology2012，，10： | 1 |
| 18 | Beta catenin directly displaces Groucho/ TLE repressors from Tcf/Lef in Wnt-mediated transcription acti- vation显示文摘 | Daniels D L Weis W I | 2005 | Nat Struct MolBiol2005，12，4： | 1 |
| 19 | The effect of rapid thermal processing (RTP) on TiN coatings deposited by PVD and the steel-turning performance of coated cemen- ted carbide 显示文摘 | Anthoy J Perry J N Steve J Bull Dmitri I P Peter C R Trevor F P Daniel E G James T John J V Robert E D Vladinmir R Alexey B M | 1999 | Surface and Coatings Technology1999，120，121： | 1 |
| 20 | Chemical teature of hardwood unbleached kraft pulps and their ECF bleachability 显示文摘 | Daniel A D I ECtuguin D V Silverstre A J D | 2004 | JPPS2004，30，4： | 1 |
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